STRINGSTRING
LOC108524923 LOC108524923 LOC108535521 LOC108535521 FN1 FN1 CDKN1B CDKN1B PIK3R1 PIK3R1 PIK3R3 PIK3R3 CKS2 CKS2 LOC108533297 LOC108533297 LOC108523439 LOC108523439 BIRC3 BIRC3 APAF1 APAF1 FHIT FHIT LAMA2 LAMA2 TRAF5 TRAF5 BCL2 BCL2 TRAF1 TRAF1 RARB RARB BIRC2 BIRC2 NFKB1 NFKB1 LAMC3 LAMC3 LAMA4 LAMA4 CASP9 CASP9 COL4A4 COL4A4 ZBTB17 ZBTB17 ITGA3 ITGA3 COL4A1 COL4A1 IKBKG IKBKG LAMA1 LAMA1 ITGAV ITGAV PIK3CA PIK3CA RELA RELA TRAF4 TRAF4 CDK4 CDK4 RB1 RB1 ITGB1 ITGB1 LAMC2 LAMC2 LAMB2 LAMB2 GADD45B GADD45B LAMA3 LAMA3 PTGS2 PTGS2 ITGA2B ITGA2B CHUK CHUK DDB2 DDB2 GADD45G GADD45G CCND1 CCND1 CKS1B CKS1B POLK POLK IKBKB IKBKB COL4A2 COL4A2 TP53 TP53 LAMB3 LAMB3 COL4A3 COL4A3 LOC108522717 LOC108522717 LAMC1 LAMC1 RXRG RXRG TRAF2 TRAF2 SKP2 SKP2 RXRB RXRB E2F2 E2F2 MYC MYC AKT2 AKT2 CCNE2 CCNE2 AKT3 AKT3 PTEN PTEN ITGA6 ITGA6 ITGA2 ITGA2 PIK3CD PIK3CD BAX BAX TRAF6 TRAF6 BAK1 BAK1 RXRA RXRA GADD45A GADD45A NFKBIA NFKBIA MAX MAX E2F3 E2F3 NOS2 NOS2 CDK6 CDK6 TRAF3 TRAF3 LAMB4 LAMB4 BIRC7 BIRC7
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108524923Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC108535521Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
FN1Fibronectin 1. (2477 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
LOC108533297Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC108523439Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1228 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
LAMA2Laminin subunit alpha 2. (3094 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (563 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TRAF1TNF receptor-associated factor. (416 aa)
RARBRetinoic acid receptor beta. (448 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
LAMC3Laminin subunit gamma 3. (1535 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (372 aa)
COL4A4Collagen type IV alpha 4 chain. (1690 aa)
ZBTB17Zinc finger and BTB domain containing 17. (803 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1087 aa)
COL4A1Collagen type IV alpha 1 chain. (1668 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
RELAUncharacterized protein. (282 aa)
TRAF4TNF receptor-associated factor. (463 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
RB1RB transcriptional corepressor 1. (815 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (937 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
LAMA3Laminin subunit alpha 3. (3324 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1105 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
CCND1Cyclin D1. (156 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
POLKDNA polymerase kappa. (866 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
COL4A2Collagen type IV alpha 2 chain. (1712 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
COL4A3Collagen type IV alpha 3 chain. (1644 aa)
LOC108522717Uncharacterized protein. (1434 aa)
LAMC1Laminin subunit gamma 1. (1587 aa)
RXRGRetinoid X receptor gamma. (463 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
RXRBRetinoid X receptor beta. (508 aa)
E2F2E2F transcription factor 2. (437 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (403 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
PTENUncharacterized protein. (555 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
RXRARetinoid X receptor alpha. (492 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
MAXMYC associated factor X. (162 aa)
E2F3E2F transcription factor 3. (465 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
TRAF3TNF receptor-associated factor. (477 aa)
LAMB4Laminin subunit beta 4. (1711 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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