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TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) | ||||
TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa) | ||||
CD47 | CD47 molecule. (323 aa) | ||||
ACSBG1 | Acyl-CoA synthetase bubblegum family member 1. (723 aa) | ||||
LOC104676775 | Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa) | ||||
HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa) | ||||
TTC39C | Tetratricopeptide repeat domain 39C. (594 aa) |