STRINGSTRING
EIF4EBP1 EIF4EBP1 LOC104669505 LOC104669505 ENSRROP00000000616 ENSRROP00000000616 CTNNA1 CTNNA1 PSCA PSCA USP10 USP10 ENSRROP00000001728 ENSRROP00000001728 AKT1 AKT1 CERS2 CERS2 CMTM5 CMTM5 RNF113A RNF113A DSC1 DSC1 FBXO25 FBXO25 ENSRROP00000004403 ENSRROP00000004403 NOP56 NOP56 STEAP4 STEAP4 TNF TNF PGRMC1 PGRMC1 LOC104676447 LOC104676447 NDRG1 NDRG1 TMPO TMPO ENSRROP00000007775 ENSRROP00000007775 TFRC TFRC STK39 STK39 NCL NCL HNRNPA3 HNRNPA3 ENSRROP00000009768 ENSRROP00000009768 ENSRROP00000010745 ENSRROP00000010745 TMEM37 TMEM37 OAS3 OAS3 TOP2B TOP2B SPDEF SPDEF G3BP1 G3BP1 ENSRROP00000011675 ENSRROP00000011675 LOC104655869 LOC104655869 MYH9 MYH9 GAPDH GAPDH ENSRROP00000013736 ENSRROP00000013736 LOC104662872 LOC104662872 ENSRROP00000014204 ENSRROP00000014204 AMACR AMACR LOC104665405 LOC104665405 FRYL FRYL EEF1D EEF1D JPT1 JPT1 HDAC1 HDAC1 LOC104668178 LOC104668178 LOC104657043 LOC104657043 TMPRSS2 TMPRSS2 RNF113B RNF113B YBX1 YBX1 CASP3 CASP3 SCFD1 SCFD1 ENSRROP00000018465 ENSRROP00000018465 MX1 MX1 ENSRROP00000019405 ENSRROP00000019405 NSD1 NSD1 PTGES3 PTGES3 RGS3 RGS3 NCOA4 NCOA4 LOC104661203 LOC104661203 ENSRROP00000021462 ENSRROP00000021462 SPATA19 SPATA19 PERP PERP APAF1 APAF1 ENSRROP00000022173 ENSRROP00000022173 AGR2 AGR2 NKX3-1 NKX3-1 MAP1B MAP1B PWP1 PWP1 ENSRROP00000024396 ENSRROP00000024396 LOC104669602 LOC104669602 ENSRROP00000024787 ENSRROP00000024787 ENSRROP00000025491 ENSRROP00000025491 IGF2R IGF2R AR AR PFKL PFKL LOC104674840 LOC104674840 TP53 TP53 ENSRROP00000027231 ENSRROP00000027231 TMEFF2 TMEFF2 MAP4 MAP4 LOC104677352 LOC104677352 AKAP12 AKAP12 MFAP1 MFAP1 XPC XPC DNMT1 DNMT1 RALY RALY EIF5B EIF5B KLK3 KLK3 ENSRROP00000030932 ENSRROP00000030932 LOC104675640 LOC104675640 CTPS1 CTPS1 PDAP1 PDAP1 LOC104658872 LOC104658872 EIF2AK2 EIF2AK2 SKP2 SKP2 BCLAF1 BCLAF1 ARHGEF26 ARHGEF26 TRPM8 TRPM8 PSMA3 PSMA3 KIT KIT JTB JTB ENSRROP00000034891 ENSRROP00000034891 BCL2 BCL2 ARHGEF17 ARHGEF17 ENSRROP00000035789 ENSRROP00000035789 FAM229A FAM229A USP2 USP2 TIPARP TIPARP HNRNPU HNRNPU MAGED2 MAGED2 EEF1B2 EEF1B2 PRKAR2A PRKAR2A MCM2 MCM2 CSTA CSTA KLK4 KLK4 SMAD6 SMAD6 CACNA1G CACNA1G LOC104671355 LOC104671355 CD82 CD82 ENSRROP00000042387 ENSRROP00000042387 CLNS1A CLNS1A NUCKS1 NUCKS1 FOLH1 FOLH1 DKC1 DKC1 SIPA1L2 SIPA1L2 LRRC26 LRRC26 ENSRROP00000043750 ENSRROP00000043750 CTNND1 CTNND1 ZFPM1 ZFPM1 ENSRROP00000044073 ENSRROP00000044073 MTHFD1 MTHFD1 MCM3 MCM3 LOC104675844 LOC104675844 LOC104662712 LOC104662712
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
LOC104669505Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (238 aa)
ENSRROP00000000616CS domain-containing protein. (136 aa)
CTNNA1Catenin alpha 1. (906 aa)
PSCAProstate stem cell antigen. (123 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa)
ENSRROP00000001728CSD_1 domain-containing protein. (316 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CERS2Ceramide synthase 2. (423 aa)
CMTM5CKLF like MARVEL transmembrane domain containing 5. (222 aa)
RNF113ARing finger protein 113A. (343 aa)
DSC1Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (894 aa)
FBXO25F-box protein 25. (367 aa)
ENSRROP00000004403EF1_GNE domain-containing protein; Belongs to the EF-1-beta/EF-1-delta family. (205 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
STEAP4STEAP4 metalloreductase. (459 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
PGRMC1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (195 aa)
LOC104676447Uncharacterized protein. (109 aa)
NDRG1N-myc downstream regulated 1. (384 aa)
TMPOThymopoietin. (695 aa)
ENSRROP00000007775Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (241 aa)
TFRCTransferrin receptor. (760 aa)
STK39Serine/threonine kinase 39. (475 aa)
NCLUncharacterized protein. (710 aa)
HNRNPA3Uncharacterized protein. (356 aa)
ENSRROP00000009768Uncharacterized protein. (260 aa)
ENSRROP00000010745PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (225 aa)
TMEM37Transmembrane protein 37. (205 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1092 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1622 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
G3BP1G3BP stress granule assembly factor 1. (466 aa)
ENSRROP00000011675Uncharacterized protein. (270 aa)
LOC104655869Heparin binding growth factor. (154 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
ENSRROP00000013736Tudor domain-containing protein. (270 aa)
LOC104662872Uncharacterized protein. (115 aa)
ENSRROP00000014204Uncharacterized protein. (174 aa)
AMACRAlpha-methylacyl-CoA racemase. (382 aa)
LOC104665405Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (583 aa)
FRYLFRY like transcription coactivator. (3013 aa)
EEF1DUncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (692 aa)
JPT1Jupiter microtubule associated homolog 1. (181 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
LOC104668178Uncharacterized protein. (392 aa)
LOC104657043Uncharacterized protein. (229 aa)
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (532 aa)
RNF113BRing finger protein 113B. (322 aa)
YBX1CSD_1 domain-containing protein. (324 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (686 aa)
ENSRROP00000018465Uncharacterized protein. (370 aa)
MX1MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (661 aa)
ENSRROP00000019405Hist_deacetyl domain-containing protein. (352 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2695 aa)
PTGES3CS domain-containing protein. (164 aa)
RGS3Regulator of G protein signaling 3. (916 aa)
NCOA4Nuclear receptor coactivator 4. (650 aa)
LOC104661203CSD_1 domain-containing protein. (278 aa)
ENSRROP00000021462Uncharacterized protein. (348 aa)
SPATA19Spermatogenesis associated 19. (167 aa)
PERPP53 apoptosis effector related to PMP22. (193 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
ENSRROP00000022173EF1_GNE domain-containing protein. (202 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
NKX3-1NK3 homeobox 1. (232 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
PWP1PWP1 homolog, endonuclein. (501 aa)
ENSRROP00000024396Uncharacterized protein. (343 aa)
LOC104669602Uncharacterized protein. (640 aa)
ENSRROP00000024787Uncharacterized protein. (263 aa)
ENSRROP00000025491Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (263 aa)
IGF2RInsulin like growth factor 2 receptor. (2486 aa)
ARUncharacterized protein. (523 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (839 aa)
LOC104674840WD_REPEATS_REGION domain-containing protein. (478 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
ENSRROP00000027231THF_DHG_CYH_C domain-containing protein. (885 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
MAP4Microtubule-associated protein. (2269 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
AKAP12A-kinase anchoring protein 12. (1783 aa)
MFAP1Microfibril associated protein 1. (439 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (939 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1665 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (315 aa)
EIF5BEukaryotic translation initiation factor 5B. (1221 aa)
KLK3Kallikrein related peptidase 3; Belongs to the peptidase S1 family. (261 aa)
ENSRROP00000030932Uncharacterized protein; Belongs to the peptidase C14A family. (255 aa)
LOC104675640Tudor domain-containing protein. (294 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa)
PDAP1PP28 domain-containing protein. (181 aa)
LOC104658872Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (219 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (550 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
BCLAF1BCL2 associated transcription factor 1. (921 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (869 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
PSMA3Proteasome subunit alpha type. (277 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa)
JTBJumping translocation breakpoint. (146 aa)
ENSRROP00000034891Uncharacterized protein. (345 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17. (1944 aa)
ENSRROP00000035789Uncharacterized protein. (368 aa)
FAM229AFamily with sequence similarity 229 member A. (127 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (635 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (806 aa)
MAGED2MAGE family member D2. (606 aa)
EEF1B2Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family. (225 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
MCM2DNA helicase; Belongs to the MCM family. (907 aa)
CSTACystatin A; Belongs to the cystatin family. (98 aa)
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (254 aa)
SMAD6MH2 domain-containing protein. (226 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
LOC104671355Uncharacterized protein. (199 aa)
CD82Tetraspanin. (267 aa)
ENSRROP00000042387BAH domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (691 aa)
CLNS1AUncharacterized protein. (237 aa)
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa)
FOLH1Folate hydrolase 1. (750 aa)
DKC1Dyskerin pseudouridine synthase 1. (514 aa)
SIPA1L2Signal induced proliferation associated 1 like 2. (1722 aa)
LRRC26Leucine rich repeat containing 26. (334 aa)
ENSRROP00000043750Uncharacterized protein. (147 aa)
CTNND1Catenin delta 1. (971 aa)
ZFPM1Uncharacterized protein. (143 aa)
ENSRROP00000044073Uncharacterized protein. (366 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (984 aa)
MCM3DNA helicase; Belongs to the MCM family. (828 aa)
LOC104675844Uncharacterized protein. (367 aa)
LOC104662712Uncharacterized protein. (226 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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