STRINGSTRING
NFATC2 NFATC2 LOC104658616 LOC104658616 LOC104655538 LOC104655538 CDK1 CDK1 SIRT2 SIRT2 CRKL CRKL TSC2 TSC2 AKT2 AKT2 CD83 CD83 CR2 CR2 CD28 CD28 ENSRROP00000042123 ENSRROP00000042123 CD82 CD82 PRKCA PRKCA ENSRROP00000042387 ENSRROP00000042387 ITGB2 ITGB2 EGR1 EGR1 PDE7B PDE7B ENSRROP00000043082 ENSRROP00000043082 RPS6KB2 RPS6KB2 NCL NCL NT5E NT5E ENSRROP00000008956 ENSRROP00000008956 ENSRROP00000008998 ENSRROP00000008998 SLC29A1 SLC29A1 LOC104661434 LOC104661434 BCR BCR PARP1 PARP1 DOCK10 DOCK10 SETD2 SETD2 ENSRROP00000010437 ENSRROP00000010437 CDR2 CDR2 DKC1 DKC1 ITGB1 ITGB1 FMNL1 FMNL1 PLCG2 PLCG2 NPM1 NPM1 PRKDC PRKDC PHRF1 PHRF1 NFKB1 NFKB1 BAG6 BAG6 LOC104675305 LOC104675305 UHRF1 UHRF1 ENSRROP00000045472 ENSRROP00000045472 EIF4EBP1 EIF4EBP1 SMARCA4 SMARCA4 AFF1 AFF1 ENSRROP00000045760 ENSRROP00000045760 PDE4A PDE4A DGCR8 DGCR8 SBF1 SBF1 ENSRROP00000011408 ENSRROP00000011408 CDK6 CDK6 EIF2S1 EIF2S1 ENSRROP00000011759 ENSRROP00000011759 XRCC6 XRCC6 LOC104682584 LOC104682584 MYH9 MYH9 ENSRROP00000012273 ENSRROP00000012273 STAT5B STAT5B ENSRROP00000012616 ENSRROP00000012616 GAPDH GAPDH CD38 CD38 CD47 CD47 CDK2 CDK2 BCL11B BCL11B LCK LCK RELB RELB MYBL2 MYBL2 SF3B1 SF3B1 HDAC9 HDAC9 SELL SELL HNRNPK HNRNPK PTPN11 PTPN11 NUP98 NUP98 ENSRROP00000015381 ENSRROP00000015381 HDAC1 HDAC1 XRCC5 XRCC5 ENSRROP00000015769 ENSRROP00000015769 SHC1 SHC1 CD7 CD7 LOC104676775 LOC104676775 ABL1 ABL1 WEE1 WEE1 ICAM1 ICAM1 LOC104659451 LOC104659451 HDAC2 HDAC2 ENSRROP00000017891 ENSRROP00000017891 ENSRROP00000017997 ENSRROP00000017997 ENSRROP00000018014 ENSRROP00000018014 TCF3 TCF3 ALB ALB CD96 CD96 CD247 CD247 ENSRROP00000019405 ENSRROP00000019405 DVL2 DVL2 ADAR ADAR NSD2 NSD2 SRC SRC SYK SYK BAD BAD ETV6 ETV6 LOC104653593 LOC104653593 EZH2 EZH2 ENSRROP00000020528 ENSRROP00000020528 LOC104667647 LOC104667647 CANX CANX SIRT1 SIRT1 CARD11 CARD11 ENSRROP00000021422 ENSRROP00000021422 PIK3R1 PIK3R1 TXNRD1 TXNRD1 CCNH CCNH PTPRC PTPRC LOC104666830 LOC104666830 RAD9A RAD9A USP9Y USP9Y RIPK1 RIPK1 CREB1 CREB1 KMT2D KMT2D LOC104675682 LOC104675682 MED12 MED12 SPEN SPEN ENSRROP00000023796 ENSRROP00000023796 DOCK2 DOCK2 CADM1 CADM1 CD1C CD1C LOC104679892 LOC104679892 HDAC4 HDAC4 STAG2 STAG2 GLIS2 GLIS2 LOC104669602 LOC104669602 SQSTM1 SQSTM1 MAPK1 MAPK1 PLCG1 PLCG1 PTPN23 PTPN23 BOK BOK IKBKB IKBKB ENSRROP00000025491 ENSRROP00000025491 CCNL2 CCNL2 MAPK14 MAPK14 IRAK4 IRAK4 BCL11A BCL11A IL2RG IL2RG ITK ITK LCP2 LCP2 CDT1 CDT1 SUZ12 SUZ12 ARHGEF1 ARHGEF1 SLC2A1 SLC2A1 LOC104669094 LOC104669094 ENSRROP00000027580 ENSRROP00000027580 MCM7 MCM7 EP300 EP300 NOTCH2 NOTCH2 SEMA4D SEMA4D BCL2L11 BCL2L11 LOC104675322 LOC104675322 ITGAL ITGAL PTPN6 PTPN6 LOC104677352 LOC104677352 FOS FOS CTCF CTCF CFL1 CFL1 CCNT2 CCNT2 MLLT3 MLLT3 CD5 CD5 DNMT1 DNMT1 HSPA4 HSPA4 PKM PKM SLC3A2 SLC3A2 SLAMF6 SLAMF6 CTNNB1 CTNNB1 IKZF1 IKZF1 LMNB1 LMNB1 USP16 USP16 E2F1 E2F1 CBL CBL CD1D CD1D AKT1S1 AKT1S1 ILRUN ILRUN KMT2A KMT2A MAPK3 MAPK3 ENSRROP00000032123 ENSRROP00000032123 MAML1 MAML1 BIRC2 BIRC2 CSNK1E CSNK1E LEF1 LEF1 ADAM10 ADAM10 BRCA1 BRCA1 STAT1 STAT1 ABCC1 ABCC1 ENSRROP00000034135 ENSRROP00000034135 GRB2 GRB2 CDK7 CDK7 LOC104665083 LOC104665083 TNFRSF8 TNFRSF8 ZAP70 ZAP70 USP9X USP9X CD44 CD44 HSP90AA1 HSP90AA1 ATG7 ATG7 RPS6KB1 RPS6KB1 FADD FADD CCND3 CCND3 WAS WAS ITPR3 ITPR3 LOC104674091 LOC104674091 LOC104661278 LOC104661278 ENSRROP00000036200 ENSRROP00000036200 TNFAIP3 TNFAIP3 RAF1 RAF1 ZEB1 ZEB1 ENSRROP00000037288 ENSRROP00000037288 IBTK IBTK RUNX1 RUNX1 SRSF2 SRSF2 PDCD4 PDCD4 EGR2 EGR2 CD226 CD226 PTK7 PTK7 HLA-E HLA-E TIAM1 TIAM1 TFRC TFRC THRAP3 THRAP3 LOC104663422 LOC104663422 NR3C1 NR3C1 FOXO3 FOXO3 ZBTB5 ZBTB5 PIK3R2 PIK3R2 PLXNB1 PLXNB1 SRSF8 SRSF8 PECAM1 PECAM1 BMP2K BMP2K PRKACB PRKACB ENSRROP00000004791 ENSRROP00000004791 JAK3 JAK3 GSK3A GSK3A PML PML TET2 TET2 ITGA4 ITGA4 LOC104666756 LOC104666756 BRD2 BRD2 BRAF BRAF LOC104659425 LOC104659425 ENSRROP00000002311 ENSRROP00000002311 TP53BP1 TP53BP1 ACD ACD MDC1 MDC1 ENSRROP00000001510 ENSRROP00000001510 EIF4G1 EIF4G1 ENSRROP00000000669 ENSRROP00000000669 ENSRROP00000000541 ENSRROP00000000541 LOC104666382 LOC104666382 CREBBP CREBBP ASXL1 ASXL1 ENSRROP00000000058 ENSRROP00000000058 ENSRROP00000000053 ENSRROP00000000053 CD48 CD48
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NFATC2Nuclear factor of activated T cells 2. (932 aa)
LOC104658616RRM domain-containing protein. (256 aa)
LOC104655538Fork-head domain-containing protein. (464 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (370 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
TSC2TSC complex subunit 2. (1807 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CD83CD83 molecule. (205 aa)
CR2Complement C3d receptor 2. (1093 aa)
CD28CD28 molecule. (220 aa)
ENSRROP00000042123Uncharacterized protein. (251 aa)
CD82Tetraspanin. (267 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ENSRROP00000042387BAH domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (691 aa)
ITGB2Integrin beta. (769 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa)
PDE7BPhosphodiesterase. (505 aa)
ENSRROP00000043082ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (149 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
NCLUncharacterized protein. (710 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
ENSRROP00000008956Uncharacterized protein. (277 aa)
ENSRROP00000008998Uncharacterized protein; Belongs to the LDH/MDH superfamily. (376 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (522 aa)
LOC104661434Uncharacterized protein. (271 aa)
BCRBCR activator of RhoGEF and GTPase. (1064 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2180 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
ENSRROP00000010437Uncharacterized protein. (235 aa)
CDR2Cerebellar degeneration related protein 2. (454 aa)
DKC1Dyskerin pseudouridine synthase 1. (514 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
FMNL1Formin like 1. (903 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
NPM1Nucleophosmin 1. (294 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4159 aa)
PHRF1PHD and ring finger domains 1. (1648 aa)
NFKB1Nuclear factor kappa B subunit 1. (975 aa)
BAG6BCL2 associated athanogene 6. (1129 aa)
LOC104675305IG domain-containing protein. (257 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (859 aa)
ENSRROP00000045472ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (185 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
AFF1AF4/FMR2 family member 1. (1221 aa)
ENSRROP00000045760Uncharacterized protein. (264 aa)
PDE4APhosphodiesterase. (886 aa)
DGCR8DGCR8 microprocessor complex subunit. (773 aa)
SBF1SET binding factor 1. (1899 aa)
ENSRROP00000011408RBD domain-containing protein. (482 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (295 aa)
ENSRROP00000011759Uncharacterized protein. (274 aa)
XRCC6X-ray repair cross complementing 6. (617 aa)
LOC104682584HATPase_c domain-containing protein. (674 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
ENSRROP00000012273ATG7_N domain-containing protein. (76 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
ENSRROP00000012616Uncharacterized protein. (280 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
CD38CD38 molecule. (301 aa)
CD47CD47 molecule. (323 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (870 aa)
LCKTyrosine-protein kinase. (561 aa)
RELBRELB proto-oncogene, NF-kB subunit. (541 aa)
MYBL2Uncharacterized protein. (868 aa)
SF3B1Splicing factor 3b subunit 1. (1304 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
HNRNPKUncharacterized protein. (464 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
NUP98Nucleoporin 98. (1799 aa)
ENSRROP00000015381Uncharacterized protein. (406 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
ENSRROP00000015769Uncharacterized protein. (279 aa)
SHC1SHC adaptor protein 1. (574 aa)
CD7CD7 molecule. (241 aa)
LOC104676775Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
WEE1WEE1 G2 checkpoint kinase. (433 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
LOC104659451Uncharacterized protein. (99 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
ENSRROP00000017891Uncharacterized protein; Belongs to the LDH/MDH superfamily. (161 aa)
ENSRROP00000017997Uncharacterized protein. (654 aa)
ENSRROP00000018014Protein kinase domain-containing protein. (315 aa)
TCF3Transcription factor 3. (655 aa)
ALBAlbumin. (604 aa)
CD96CD96 molecule. (575 aa)
CD247CD247 molecule. (173 aa)
ENSRROP00000019405Hist_deacetyl domain-containing protein. (352 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
ADARAdenosine deaminase RNA specific. (1241 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1365 aa)
SRCTyrosine-protein kinase. (540 aa)
SYKTyrosine-protein kinase. (635 aa)
BADBCL2 associated agonist of cell death. (167 aa)
ETV6ETS variant 6. (451 aa)
LOC104653593Uncharacterized protein. (277 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (737 aa)
ENSRROP00000020528Uncharacterized protein. (630 aa)
LOC104667647L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (360 aa)
CANXCalnexin. (600 aa)
SIRT1Sirtuin 1. (746 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
ENSRROP00000021422Uncharacterized protein. (534 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TXNRD1Glutaredoxin domain-containing protein. (648 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1311 aa)
LOC104666830Uncharacterized protein. (286 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (420 aa)
USP9YUbiquitin specific peptidase 9 Y-linked; Belongs to the peptidase C19 family. (2551 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
KMT2DLysine methyltransferase 2D. (5538 aa)
LOC104675682HATPase_c domain-containing protein. (671 aa)
MED12Med12-PQL domain-containing protein. (323 aa)
SPENSpen family transcriptional repressor. (3663 aa)
ENSRROP00000023796Uncharacterized protein. (778 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
CADM1Cell adhesion molecule 1. (475 aa)
CD1CCD1c molecule. (332 aa)
LOC104679892BRCT domain-containing protein. (96 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1085 aa)
STAG2Stromal antigen 2. (1268 aa)
GLIS2GLIS family zinc finger 2. (524 aa)
LOC104669602Uncharacterized protein. (640 aa)
SQSTM1Sequestosome 1. (451 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1629 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
ENSRROP00000025491Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (263 aa)
CCNL2Cyclin L2; Belongs to the cyclin family. (481 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
ITKTyrosine-protein kinase. (620 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
CDT1Chromatin licensing and DNA replication factor 1. (513 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
LOC104669094Pyruvate kinase; Belongs to the pyruvate kinase family. (448 aa)
ENSRROP00000027580Uncharacterized protein. (220 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (626 aa)
EP300E1A binding protein p300. (2413 aa)
NOTCH2Notch receptor 2. (2471 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
LOC104675322IG domain-containing protein. (193 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CTCFCCCTC-binding factor. (727 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (212 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
MLLT3MLLT3 super elongation complex subunit. (554 aa)
CD5CD5 molecule. (499 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1665 aa)
HSPA4Heat shock protein family A (Hsp70) member 4. (840 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
SLC3A2Solute carrier family 3 member 2. (629 aa)
SLAMF6SLAM family member 6. (331 aa)
CTNNB1Catenin beta 1. (781 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
USP16Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (826 aa)
E2F1E2F transcription factor 1. (485 aa)
CBLCbl proto-oncogene. (906 aa)
CD1DCD1d molecule. (337 aa)
AKT1S1AKT1 substrate 1. (276 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (298 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3914 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSRROP00000032123Uncharacterized protein. (305 aa)
MAML1Mastermind like transcriptional coactivator 1. (936 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1836 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
ABCC1ATP binding cassette subfamily C member 1. (1531 aa)
ENSRROP00000034135Poly [ADP-ribose] polymerase. (856 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
LOC104665083Uncharacterized protein. (482 aa)
TNFRSF8TNF receptor superfamily member 8. (595 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
USP9XUncharacterized protein. (278 aa)
CD44CD44 molecule (Indian blood group). (742 aa)
HSP90AA1HATPase_c domain-containing protein. (657 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (703 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
WASWASP actin nucleation promoting factor. (500 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
LOC104674091Ig-like domain-containing protein. (405 aa)
LOC104661278Uncharacterized protein. (307 aa)
ENSRROP00000036200Uncharacterized protein. (491 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
RAF1Uncharacterized protein. (668 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
ENSRROP00000037288L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (354 aa)
IBTKInhibitor of Bruton tyrosine kinase. (1352 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (482 aa)
SRSF2Serine and arginine rich splicing factor 2. (221 aa)
PDCD4Programmed cell death 4. (470 aa)
EGR2Early growth response 2. (476 aa)
CD226CD226 molecule. (336 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1591 aa)
TFRCTransferrin receptor. (760 aa)
THRAP3Thyroid hormone receptor associated protein 3. (955 aa)
LOC104663422Uncharacterized protein. (297 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (778 aa)
FOXO3Forkhead box O3. (617 aa)
ZBTB5Zinc finger and BTB domain containing 5. (677 aa)
PIK3R2Uncharacterized protein. (647 aa)
PLXNB1Plexin B1. (2141 aa)
SRSF8Serine and arginine rich splicing factor 8. (287 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (756 aa)
BMP2KBMP2 inducible kinase. (1073 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSRROP00000004791Uncharacterized protein. (65 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (428 aa)
PMLPromyelocytic leukemia. (882 aa)
TET2Tet methylcytosine dioxygenase 2. (2022 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
LOC104666756Uncharacterized protein. (189 aa)
BRD2Uncharacterized protein. (836 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (761 aa)
LOC104659425ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (158 aa)
ENSRROP00000002311Ku domain-containing protein. (539 aa)
TP53BP1Tumor protein p53 binding protein 1. (1976 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (527 aa)
MDC1Mediator of DNA damage checkpoint 1. (2029 aa)
ENSRROP00000001510Uncharacterized protein. (425 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1604 aa)
ENSRROP00000000669Fork-head domain-containing protein. (435 aa)
ENSRROP00000000541Ldh_1_N domain-containing protein. (91 aa)
LOC104666382Uncharacterized protein. (427 aa)
CREBBPCREB binding protein. (2442 aa)
ASXL1ASXL transcriptional regulator 1. (1536 aa)
ENSRROP00000000058Uncharacterized protein. (224 aa)
ENSRROP00000000053Pyruvate kinase; Belongs to the pyruvate kinase family. (542 aa)
CD48CD48 molecule. (294 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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