(16 nodes) Mixed, incl. Tissue factor, and Response to type III interferon network (Rhinopithecus roxellana)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL10RB	Interleukin 10 receptor subunit beta. (325 aa)
	TYK2	Tyrosine-protein kinase. (1187 aa)
	IL22RA1	Interleukin 22 receptor subunit alpha 1. (571 aa)
	IL22	Interleukin 22. (179 aa)
	TP53BP2	Tumor protein p53 binding protein 2. (1134 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
	IFNAR2	Uncharacterized protein. (516 aa)
	IFNAR1	Interferon alpha and beta receptor subunit 1. (558 aa)
	IFNE	Interferon epsilon. (196 aa)
	IFNGR2	Interferon gamma receptor 2. (347 aa)
	IL10RA	Interleukin 10 receptor subunit alpha. (578 aa)
	IFNGR1	Interferon gamma receptor 1. (489 aa)
	IFNLR1	Interferon lambda receptor 1. (523 aa)
	JAK1	Tyrosine-protein kinase. (1154 aa)
	IL10	Interleukin 10. (178 aa)
	IFNL1	Interferon lambda 1. (202 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFNAR1	IFNAR2	ENSRROP00000019718	ENSRROP00000019471	Interferon alpha and beta receptor subunit 1.	Uncharacterized protein.	0.997
IFNAR1	IFNE	ENSRROP00000019718	ENSRROP00000019929	Interferon alpha and beta receptor subunit 1.	Interferon epsilon.	0.981
IFNAR1	IFNG	ENSRROP00000019718	ENSRROP00000017582	Interferon alpha and beta receptor subunit 1.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.955
IFNAR1	IFNGR1	ENSRROP00000019718	ENSRROP00000022477	Interferon alpha and beta receptor subunit 1.	Interferon gamma receptor 1.	0.961
IFNAR1	IFNGR2	ENSRROP00000019718	ENSRROP00000021525	Interferon alpha and beta receptor subunit 1.	Interferon gamma receptor 2.	0.946
IFNAR1	IFNL1	ENSRROP00000019718	ENSRROP00000043178	Interferon alpha and beta receptor subunit 1.	Interferon lambda 1.	0.866
IFNAR1	IFNLR1	ENSRROP00000019718	ENSRROP00000037155	Interferon alpha and beta receptor subunit 1.	Interferon lambda receptor 1.	0.860
IFNAR1	IL10	ENSRROP00000019718	ENSRROP00000042923	Interferon alpha and beta receptor subunit 1.	Interleukin 10.	0.901
IFNAR1	IL10RA	ENSRROP00000019718	ENSRROP00000021996	Interferon alpha and beta receptor subunit 1.	Interleukin 10 receptor subunit alpha.	0.738
IFNAR1	IL22	ENSRROP00000019718	ENSRROP00000014316	Interferon alpha and beta receptor subunit 1.	Interleukin 22.	0.886
IFNAR1	IL22RA1	ENSRROP00000019718	ENSRROP00000013304	Interferon alpha and beta receptor subunit 1.	Interleukin 22 receptor subunit alpha 1.	0.723
IFNAR1	JAK1	ENSRROP00000019718	ENSRROP00000040577	Interferon alpha and beta receptor subunit 1.	Tyrosine-protein kinase.	0.995
IFNAR1	TYK2	ENSRROP00000019718	ENSRROP00000013030	Interferon alpha and beta receptor subunit 1.	Tyrosine-protein kinase.	0.998
IFNAR2	IFNAR1	ENSRROP00000019471	ENSRROP00000019718	Uncharacterized protein.	Interferon alpha and beta receptor subunit 1.	0.997
IFNAR2	IFNE	ENSRROP00000019471	ENSRROP00000019929	Uncharacterized protein.	Interferon epsilon.	0.986
IFNAR2	IFNG	ENSRROP00000019471	ENSRROP00000017582	Uncharacterized protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.956
IFNAR2	IFNGR1	ENSRROP00000019471	ENSRROP00000022477	Uncharacterized protein.	Interferon gamma receptor 1.	0.967
IFNAR2	IFNGR2	ENSRROP00000019471	ENSRROP00000021525	Uncharacterized protein.	Interferon gamma receptor 2.	0.958
IFNAR2	IFNL1	ENSRROP00000019471	ENSRROP00000043178	Uncharacterized protein.	Interferon lambda 1.	0.815
IFNAR2	IFNLR1	ENSRROP00000019471	ENSRROP00000037155	Uncharacterized protein.	Interferon lambda receptor 1.	0.472