STRINGSTRING
LOC104668178 LOC104668178 CTBP2 CTBP2 CHD6 CHD6 NEK6 NEK6 EPAS1 EPAS1 CDK9 CDK9 PHF1 PHF1 NR1H4 NR1H4 STAT1 STAT1 LEF1 LEF1 THAP7 THAP7 TEAD2 TEAD2 RUNX3 RUNX3 SMARCD3 SMARCD3 CTNNB1 CTNNB1 SREBF1 SREBF1 MED1 MED1 CCNT2 CCNT2 CTCF CTCF FOS FOS LOC104677352 LOC104677352 LOC104667986 LOC104667986 EP300 EP300 SUZ12 SUZ12 ZBTB16 ZBTB16 NR5A2 NR5A2 AR AR STK36 STK36 USP11 USP11 PAX6 PAX6 GATA3 GATA3 CBX3 CBX3 CREB3 CREB3 WIZ WIZ GATA1 GATA1 EZH2 EZH2 ENSRROP00000019405 ENSRROP00000019405 FAM89B FAM89B ZBTB17 ZBTB17 EED EED LOC104665620 LOC104665620 PBX1 PBX1 RARA RARA VGLL4 VGLL4 PER1 PER1 TERT TERT MYC MYC CIT CIT LCOR LCOR ATF7 ATF7 HDAC1 HDAC1 PPARA PPARA HAND2 HAND2 MTF2 MTF2 ELOC ELOC ZNF644 ZNF644 PER2 PER2 ENSRROP00000012193 ENSRROP00000012193 LOC104655869 LOC104655869 ZNF618 ZNF618 SP1 SP1 PPARD PPARD MED25 MED25 EHMT2 EHMT2 ENSRROP00000008767 ENSRROP00000008767 THRB THRB NFATC1 NFATC1 LOC104657870 LOC104657870 LOC104676447 LOC104676447 ENSRROP00000007230 ENSRROP00000007230 ZBTB7A ZBTB7A HDAC3 HDAC3 LOC104674456 LOC104674456 SMAD3 SMAD3 BCL6 BCL6 LOC104670765 LOC104670765 ENSRROP00000005879 ENSRROP00000005879 NR1D1 NR1D1 ENSRROP00000005469 ENSRROP00000005469 HMGA1 HMGA1 HNF1A HNF1A ENSRROP00000004459 ENSRROP00000004459 RELA RELA HAND1 HAND1 ZBTB49 ZBTB49 ETS1 ETS1 ZBTB8A ZBTB8A GATA6 GATA6 HIF1A HIF1A CREBBP CREBBP SMARCA4 SMARCA4 ENSRROP00000045588 ENSRROP00000045588 CTBP1 CTBP1 NFKB1 NFKB1 NFE2L2 NFE2L2 TRERF1 TRERF1 LOC104678360 LOC104678360 ENSRROP00000043547 ENSRROP00000043547 SMAD4 SMAD4 TP73 TP73 ENSRROP00000042897 ENSRROP00000042897 NR5A1 NR5A1 RORA RORA UBE2I UBE2I EHMT1 EHMT1 HDAC6 HDAC6 BAIAP2 BAIAP2 PER3 PER3 PHF12 PHF12 ENSRROP00000039400 ENSRROP00000039400 GATA2 GATA2 RXRA RXRA SIX3 SIX3 CNOT2 CNOT2 CHD4 CHD4 RUNX1 RUNX1 LMO2 LMO2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC104668178Uncharacterized protein. (392 aa)
CTBP2C-terminal binding protein 2. (985 aa)
CHD6Chromodomain helicase DNA binding protein 6. (1457 aa)
NEK6NIMA related kinase 6. (369 aa)
EPAS1Endothelial PAS domain protein 1. (865 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
PHF1PHD finger protein 1. (567 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
THAP7THAP domain containing 7. (309 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (415 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (386 aa)
CTNNB1Catenin beta 1. (781 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
CTCFCCCTC-binding factor. (727 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
LOC104667986Uncharacterized protein. (96 aa)
EP300E1A binding protein p300. (2413 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (538 aa)
ARUncharacterized protein. (523 aa)
STK36Serine/threonine kinase 36. (1315 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (976 aa)
PAX6Paired box 6. (458 aa)
GATA3GATA binding protein 3. (444 aa)
CBX3Uncharacterized protein. (183 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
WIZWIZ zinc finger. (968 aa)
GATA1GATA binding protein 1. (413 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (737 aa)
ENSRROP00000019405Hist_deacetyl domain-containing protein. (352 aa)
FAM89BFamily with sequence similarity 89 member B. (189 aa)
ZBTB17Zinc finger and BTB domain containing 17. (803 aa)
EEDEmbryonic ectoderm development. (466 aa)
LOC104665620Uncharacterized protein. (248 aa)
PBX1PBX homeobox 1. (430 aa)
RARARetinoic acid receptor alpha. (478 aa)
VGLL4Vestigial like family member 4. (296 aa)
PER1Period circadian regulator 1. (1292 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2052 aa)
LCORLigand dependent nuclear receptor corepressor. (1556 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
PPARAPeroxisome proliferator activated receptor alpha. (398 aa)
HAND2Heart and neural crest derivatives expressed 2. (287 aa)
MTF2Metal response element binding transcription factor 2. (593 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ZNF644Zinc finger protein 644. (1368 aa)
PER2Period circadian regulator 2. (1253 aa)
ENSRROP00000012193Uncharacterized protein. (185 aa)
LOC104655869Heparin binding growth factor. (154 aa)
ZNF618Zinc finger protein 618. (954 aa)
SP1Sp1 transcription factor. (786 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
MED25Mediator complex subunit 25. (747 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1237 aa)
ENSRROP00000008767Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (451 aa)
THRBThyroid hormone receptor beta. (476 aa)
NFATC1Nuclear factor of activated T cells 1. (895 aa)
LOC104657870Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
LOC104676447Uncharacterized protein. (109 aa)
ENSRROP00000007230Uncharacterized protein. (193 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
LOC104674456Ubiquitin-like domain-containing protein. (118 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
BCL6BCL6 transcription repressor. (706 aa)
LOC104670765Uncharacterized protein. (248 aa)
ENSRROP00000005879Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (390 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
ENSRROP00000005469Uncharacterized protein. (53 aa)
HMGA1Uncharacterized protein. (105 aa)
HNF1AHNF1 homeobox A. (662 aa)
ENSRROP00000004459Skp1_POZ domain-containing protein. (93 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
ZBTB49Zinc finger and BTB domain containing 49. (764 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
ZBTB8AZinc finger and BTB domain containing 8A. (441 aa)
GATA6GATA binding protein 6. (548 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
CREBBPCREB binding protein. (2442 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
ENSRROP00000045588Ubiquitin-like domain-containing protein. (137 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
NFKB1Nuclear factor kappa B subunit 1. (975 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
TRERF1Transcriptional regulating factor 1. (1219 aa)
LOC104678360Nuclear receptor domain-containing protein. (231 aa)
ENSRROP00000043547Uncharacterized protein. (106 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
ENSRROP00000042897Uncharacterized protein. (165 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
RORARAR related orphan receptor A. (555 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (231 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1281 aa)
HDAC6Histone deacetylase 6. (1258 aa)
BAIAP2BAI1 associated protein 2. (532 aa)
PER3Period circadian regulator 3. (1178 aa)
PHF12PHD finger protein 12. (1004 aa)
ENSRROP00000039400Uncharacterized protein; Belongs to the SKP1 family. (100 aa)
GATA2GATA binding protein 2. (480 aa)
RXRARetinoid X receptor alpha. (481 aa)
SIX3SIX homeobox 3. (332 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (540 aa)
CHD4Uncharacterized protein. (1913 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (482 aa)
LMO2LIM domain only 2. (218 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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