53 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSRROP00000007230	Uncharacterized protein. (193 aa)
	STAT1	Signal transducer and activator of transcription. (787 aa)
	LEF1	Lymphoid enhancer binding factor 1. (399 aa)
	THAP7	THAP domain containing 7. (309 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (415 aa)
	LOC104677352	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
	SUZ12	SUZ12 polycomb repressive complex 2 subunit. (739 aa)
	ZBTB16	Zinc finger and BTB domain containing 16. (673 aa)
	STK36	Serine/threonine kinase 36. (1315 aa)
	USP11	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (976 aa)
	WIZ	WIZ zinc finger. (968 aa)
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (737 aa)
	ENSRROP00000019405	Hist_deacetyl domain-containing protein. (352 aa)
	FAM89B	Family with sequence similarity 89 member B. (189 aa)
	EED	Embryonic ectoderm development. (466 aa)
	PBX1	PBX homeobox 1. (430 aa)
	PER1	Period circadian regulator 1. (1292 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
	MTF2	Metal response element binding transcription factor 2. (593 aa)
	ELOC	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
	ZNF644	Zinc finger protein 644. (1368 aa)
	PER2	Period circadian regulator 2. (1253 aa)
	LOC104655869	Heparin binding growth factor. (154 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1237 aa)
	ENSRROP00000008767	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (451 aa)
	LOC104657870	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
	LOC104676447	Uncharacterized protein. (109 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (584 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	LOC104674456	Ubiquitin-like domain-containing protein. (118 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	ENSRROP00000005879	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (390 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (613 aa)
	ENSRROP00000005469	Uncharacterized protein. (53 aa)
	ENSRROP00000004459	Skp1_POZ domain-containing protein. (93 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (485 aa)
	ENSRROP00000045588	Ubiquitin-like domain-containing protein. (137 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
	LOC104678360	Nuclear receptor domain-containing protein. (231 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
	RORA	RAR related orphan receptor A. (555 aa)
	EHMT1	Euchromatic histone lysine methyltransferase 1. (1281 aa)
	HDAC6	Histone deacetylase 6. (1258 aa)
	PER3	Period circadian regulator 3. (1178 aa)
	PHF12	PHD finger protein 12. (1004 aa)
	ENSRROP00000039400	Uncharacterized protein; Belongs to the SKP1 family. (100 aa)
	SIX3	SIX homeobox 3. (332 aa)
	CNOT2	CCR4-NOT transcription complex subunit 2. (540 aa)
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (482 aa)
	LCOR	Ligand dependent nuclear receptor corepressor. (1556 aa)
	CTBP2	C-terminal binding protein 2. (985 aa)
	NEK6	NIMA related kinase 6. (369 aa)
	PHF1	PHD finger protein 1. (567 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	ENSRROP00000019405	ENSRROP00000005956	ENSRROP00000019405	BCL6 transcription repressor.	Hist_deacetyl domain-containing protein.	0.528
BCL6	EZH2	ENSRROP00000005956	ENSRROP00000020305	BCL6 transcription repressor.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.441
BCL6	HDAC1	ENSRROP00000005956	ENSRROP00000015472	BCL6 transcription repressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.528
BCL6	LOC104677352	ENSRROP00000005956	ENSRROP00000029153	BCL6 transcription repressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.528
BCL6	STAT1	ENSRROP00000005956	ENSRROP00000033613	BCL6 transcription repressor.	Signal transducer and activator of transcription.	0.415
CTBP1	CTBP2	ENSRROP00000044953	ENSRROP00000036397	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.973
CTBP1	EHMT1	ENSRROP00000044953	ENSRROP00000041474	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Euchromatic histone lysine methyltransferase 1.	0.453
CTBP1	EHMT2	ENSRROP00000044953	ENSRROP00000009074	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Euchromatic histone lysine methyltransferase 2.	0.511
CTBP1	ENSRROP00000005879	ENSRROP00000044953	ENSRROP00000005879	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.747
CTBP1	ENSRROP00000008767	ENSRROP00000044953	ENSRROP00000008767	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.746
CTBP1	ENSRROP00000019405	ENSRROP00000044953	ENSRROP00000019405	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Hist_deacetyl domain-containing protein.	0.722
CTBP1	HDAC1	ENSRROP00000044953	ENSRROP00000015472	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.722
CTBP1	LCOR	ENSRROP00000044953	ENSRROP00000036620	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Ligand dependent nuclear receptor corepressor.	0.813
CTBP1	LEF1	ENSRROP00000044953	ENSRROP00000033077	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer binding factor 1.	0.949
CTBP1	LOC104677352	ENSRROP00000044953	ENSRROP00000029153	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.942
CTBP1	WIZ	ENSRROP00000044953	ENSRROP00000022519	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	WIZ zinc finger.	0.555
CTBP2	CTBP1	ENSRROP00000036397	ENSRROP00000044953	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.973
CTBP2	ENSRROP00000019405	ENSRROP00000036397	ENSRROP00000019405	C-terminal binding protein 2.	Hist_deacetyl domain-containing protein.	0.444
CTBP2	HDAC1	ENSRROP00000036397	ENSRROP00000015472	C-terminal binding protein 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.444
CTBP2	LCOR	ENSRROP00000036397	ENSRROP00000036620	C-terminal binding protein 2.	Ligand dependent nuclear receptor corepressor.	0.519