STRINGSTRING
TEAD2 TEAD2 NFKB1 NFKB1 TRERF1 TRERF1 LOC104678360 LOC104678360 SMAD4 SMAD4 RORA RORA GATA2 GATA2 RUNX1 RUNX1 EPAS1 EPAS1 CDK9 CDK9 STAT1 STAT1 MED1 MED1 CCNT2 CCNT2 EP300 EP300 AR AR GATA3 GATA3 GATA1 GATA1 ZBTB17 ZBTB17 LOC104665620 LOC104665620 RARA RARA VGLL4 VGLL4 TERT TERT CIT CIT LOC104668178 LOC104668178 ATF7 ATF7 PPARA PPARA HAND2 HAND2 PPARD PPARD MED25 MED25 THRB THRB NFATC1 NFATC1 SMAD3 SMAD3 LOC104670765 LOC104670765 HNF1A HNF1A RELA RELA ZBTB49 ZBTB49 ZBTB8A ZBTB8A GATA6 GATA6 HIF1A HIF1A CREBBP CREBBP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEAD2TEA domain transcription factor 2. (451 aa)
NFKB1Nuclear factor kappa B subunit 1. (975 aa)
TRERF1Transcriptional regulating factor 1. (1219 aa)
LOC104678360Nuclear receptor domain-containing protein. (231 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
RORARAR related orphan receptor A. (555 aa)
GATA2GATA binding protein 2. (480 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (482 aa)
EPAS1Endothelial PAS domain protein 1. (865 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
EP300E1A binding protein p300. (2413 aa)
ARUncharacterized protein. (523 aa)
GATA3GATA binding protein 3. (444 aa)
GATA1GATA binding protein 1. (413 aa)
ZBTB17Zinc finger and BTB domain containing 17. (803 aa)
LOC104665620Uncharacterized protein. (248 aa)
RARARetinoic acid receptor alpha. (478 aa)
VGLL4Vestigial like family member 4. (296 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2052 aa)
LOC104668178Uncharacterized protein. (392 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
PPARAPeroxisome proliferator activated receptor alpha. (398 aa)
HAND2Heart and neural crest derivatives expressed 2. (287 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
MED25Mediator complex subunit 25. (747 aa)
THRBThyroid hormone receptor beta. (476 aa)
NFATC1Nuclear factor of activated T cells 1. (895 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
LOC104670765Uncharacterized protein. (248 aa)
HNF1AHNF1 homeobox A. (662 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ZBTB49Zinc finger and BTB domain containing 49. (764 aa)
ZBTB8AZinc finger and BTB domain containing 8A. (441 aa)
GATA6GATA binding protein 6. (548 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
CREBBPCREB binding protein. (2442 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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