40 items (Rhinopithecus roxellana) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	TEAD2	TEA domain transcription factor 2. (451 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (975 aa)
	TRERF1	Transcriptional regulating factor 1. (1219 aa)
	LOC104678360	Nuclear receptor domain-containing protein. (231 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	RORA	RAR related orphan receptor A. (555 aa)
	GATA2	GATA binding protein 2. (480 aa)
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (482 aa)
	EPAS1	Endothelial PAS domain protein 1. (865 aa)
	CDK9	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
	STAT1	Signal transducer and activator of transcription. (787 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
	CCNT2	Cyclin T2; Belongs to the cyclin family. (730 aa)
	EP300	E1A binding protein p300. (2413 aa)
	AR	Uncharacterized protein. (523 aa)
	GATA3	GATA binding protein 3. (444 aa)
	GATA1	GATA binding protein 1. (413 aa)
	ZBTB17	Zinc finger and BTB domain containing 17. (803 aa)
	LOC104665620	Uncharacterized protein. (248 aa)
	RARA	Retinoic acid receptor alpha. (478 aa)
	VGLL4	Vestigial like family member 4. (296 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
	CIT	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2052 aa)
	LOC104668178	Uncharacterized protein. (392 aa)
	ATF7	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (398 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (287 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	MED25	Mediator complex subunit 25. (747 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	NFATC1	Nuclear factor of activated T cells 1. (895 aa)
	SMAD3	Mothers against decapentaplegic homolog. (480 aa)
	LOC104670765	Uncharacterized protein. (248 aa)
	HNF1A	HNF1 homeobox A. (662 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	ZBTB49	Zinc finger and BTB domain containing 49. (764 aa)
	ZBTB8A	Zinc finger and BTB domain containing 8A. (441 aa)
	GATA6	GATA binding protein 6. (548 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (826 aa)
	CREBBP	CREB binding protein. (2442 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	CREBBP	ENSRROP00000025864	ENSRROP00000000267	Uncharacterized protein.	CREB binding protein.	0.687
AR	EP300	ENSRROP00000025864	ENSRROP00000028002	Uncharacterized protein.	E1A binding protein p300.	0.693
AR	LOC104668178	ENSRROP00000025864	ENSRROP00000015607	Uncharacterized protein.	Uncharacterized protein.	0.484
AR	LOC104678360	ENSRROP00000025864	ENSRROP00000044141	Uncharacterized protein.	Nuclear receptor domain-containing protein.	0.574
AR	MED1	ENSRROP00000025864	ENSRROP00000029917	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.504
AR	RUNX1	ENSRROP00000025864	ENSRROP00000037635	Uncharacterized protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.504
AR	SMAD3	ENSRROP00000025864	ENSRROP00000006108	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.528
ATF7	CREBBP	ENSRROP00000015573	ENSRROP00000000267	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	CREB binding protein.	0.700
ATF7	EP300	ENSRROP00000015573	ENSRROP00000028002	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	E1A binding protein p300.	0.616
ATF7	GATA2	ENSRROP00000015573	ENSRROP00000039371	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	GATA binding protein 2.	0.404
ATF7	GATA3	ENSRROP00000015573	ENSRROP00000023250	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	GATA binding protein 3.	0.404
CCNT2	CDK9	ENSRROP00000029697	ENSRROP00000034594	Cyclin T2; Belongs to the cyclin family.	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.	0.998
CCNT2	SMAD4	ENSRROP00000029697	ENSRROP00000043301	Cyclin T2; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.467
CDK9	CCNT2	ENSRROP00000034594	ENSRROP00000029697	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.	Cyclin T2; Belongs to the cyclin family.	0.998
CDK9	LOC104678360	ENSRROP00000034594	ENSRROP00000044141	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.	Nuclear receptor domain-containing protein.	0.555
CDK9	MED1	ENSRROP00000034594	ENSRROP00000029917	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.940
CDK9	RELA	ENSRROP00000034594	ENSRROP00000004220	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.	RELA proto-oncogene, NF-kB subunit.	0.454
CDK9	SMAD4	ENSRROP00000034594	ENSRROP00000043301	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.623
CREBBP	AR	ENSRROP00000000267	ENSRROP00000025864	CREB binding protein.	Uncharacterized protein.	0.687
CREBBP	ATF7	ENSRROP00000000267	ENSRROP00000015573	CREB binding protein.	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	0.700