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C4A | Uncharacterized protein. (1625 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) | ||||
CD226 | CD226 molecule. (336 aa) | ||||
TNFRSF4 | TNF receptor superfamily member 4. (277 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa) | ||||
GATA2 | GATA binding protein 2. (480 aa) | ||||
TNFSF13 | TNF superfamily member 13; Belongs to the tumor necrosis factor family. (250 aa) | ||||
HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa) | ||||
RAC2 | Rac family small GTPase 2. (192 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) | ||||
ENSRROP00000039750 | MHC_I-like_Ag-recog domain-containing protein. (247 aa) | ||||
ENSRROP00000039767 | Ig-like domain-containing protein. (237 aa) | ||||
SEMA7A | Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) | ||||
ENSRROP00000040276 | MHC_I-like_Ag-recog domain-containing protein. (233 aa) | ||||
STAP1 | Signal transducing adaptor family member 1. (295 aa) | ||||
CD81 | Tetraspanin. (274 aa) | ||||
IL23R | Interleukin 23 receptor. (629 aa) | ||||
CD28 | CD28 molecule. (220 aa) | ||||
GPRC5B | G protein-coupled receptor class C group 5 member B. (549 aa) | ||||
NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) | ||||
IL18 | Interleukin 18. (211 aa) | ||||
BCL10 | BCL10 immune signaling adaptor. (316 aa) | ||||
C3 | Complement C3. (1663 aa) | ||||
ITGB2 | Integrin beta. (769 aa) | ||||
IL10 | Interleukin 10. (178 aa) | ||||
CLNK | Cytokine dependent hematopoietic cell linker. (428 aa) | ||||
PVR | PVR cell adhesion molecule. (413 aa) | ||||
PLA2G3 | Phospholipase A2 group III. (506 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (841 aa) | ||||
CLCF1 | Cardiotrophin like cytokine factor 1. (319 aa) | ||||
NFKBID | NFKB inhibitor delta. (469 aa) | ||||
IL23A | Interleukin 23 subunit alpha. (189 aa) | ||||
KMT5B | Lysine methyltransferase 5B. (885 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) | ||||
NLRP3 | NLR family pyrin domain containing 3. (1035 aa) | ||||
KMT5C | Lysine methyltransferase 5C. (461 aa) | ||||
LACC1 | Uncharacterized protein. (430 aa) | ||||
LOC104674799 | Uncharacterized protein. (97 aa) | ||||
CD1D | CD1d molecule. (337 aa) | ||||
TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) | ||||
MYB | MYB proto-oncogene, transcription factor. (761 aa) | ||||
SLAMF6 | SLAM family member 6. (331 aa) | ||||
VAMP8 | Vesicle associated membrane protein 8. (100 aa) | ||||
IL13RA2 | Interleukin 13 receptor subunit alpha 2. (339 aa) | ||||
PHB | Prohibitin. (272 aa) | ||||
KIR2DL4 | Uncharacterized protein. (237 aa) | ||||
FOXP3 | Forkhead box P3. (454 aa) | ||||
ENSRROP00000029809 | Prohibitin. (264 aa) | ||||
IL13 | Interleukin 13. (146 aa) | ||||
CD1A | CD1a molecule. (327 aa) | ||||
MAPKAPK2 | MAPK activated protein kinase 2. (322 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) | ||||
SLAMF1 | Signaling lymphocytic activation molecule family member 1. (357 aa) | ||||
MALT1 | MALT1 paracaspase. (774 aa) | ||||
ENSRROP00000028436 | Prohibitin. (290 aa) | ||||
SLC7A5 | Solute carrier family 7 member 5. (500 aa) | ||||
ENSRROP00000027696 | Uncharacterized protein. (222 aa) | ||||
CARD9 | Caspase recruitment domain family member 9. (536 aa) | ||||
ENSRROP00000027142 | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (318 aa) | ||||
ENSRROP00000026787 | Prohibitin. (190 aa) | ||||
CD37 | Tetraspanin. (311 aa) | ||||
CD177 | Uncharacterized protein. (139 aa) | ||||
TNFRSF14 | TNF receptor superfamily member 14. (283 aa) | ||||
FAM49B | Family with sequence similarity 49 member B. (324 aa) | ||||
LOC104676771 | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (369 aa) | ||||
HPX | Hemopexin. (422 aa) | ||||
DHX36 | DEAH-box helicase 36. (1008 aa) | ||||
CD40 | CD40 molecule. (278 aa) | ||||
TICAM1 | Toll like receptor adaptor molecule 1. (522 aa) | ||||
ENSRROP00000025349 | Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa) | ||||
MLH1 | MutL homolog 1. (756 aa) | ||||
CD1C | CD1c molecule. (332 aa) | ||||
INAVA | Innate immunity activator. (663 aa) | ||||
ENSRROP00000024190 | Protein kinase domain-containing protein. (137 aa) | ||||
CADM1 | Cell adhesion molecule 1. (475 aa) | ||||
DHX58 | DExH-box helicase 58. (650 aa) | ||||
EPHB2 | EPH receptor B2. (1058 aa) | ||||
SPHK2 | Sphingosine kinase 2. (665 aa) | ||||
MASP1 | Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (739 aa) | ||||
SH2D1A | SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa) | ||||
GATA3 | GATA binding protein 3. (444 aa) | ||||
IL33 | Interleukin 33. (270 aa) | ||||
ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa) | ||||
XBP1 | BZIP domain-containing protein. (380 aa) | ||||
GATA1 | GATA binding protein 1. (413 aa) | ||||
ARG1 | Arginase. (322 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1311 aa) | ||||
SPON2 | Spondin 2. (355 aa) | ||||
HLX | H2.0 like homeobox. (494 aa) | ||||
DENND1B | DENN domain containing 1B. (775 aa) | ||||
TBX21 | T-box transcription factor 21. (531 aa) | ||||
SIRT1 | Sirtuin 1. (746 aa) | ||||
CD300A | CD300a molecule. (296 aa) | ||||
CD74 | CD74 molecule. (294 aa) | ||||
NCR3 | Natural cytotoxicity triggering receptor 3. (189 aa) | ||||
SYK | Tyrosine-protein kinase. (635 aa) | ||||
NFKBIZ | NFKB inhibitor zeta. (723 aa) | ||||
NSD2 | Nuclear receptor binding SET domain protein 2. (1365 aa) | ||||
BTK | Tyrosine-protein kinase. (690 aa) | ||||
CD160 | CD160 molecule. (232 aa) | ||||
MR1 | Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (337 aa) | ||||
DDX21 | DExD-box helicase 21. (783 aa) | ||||
FCN3 | Ficolin 3. (320 aa) | ||||
EXOSC3 | Exosome component 3. (275 aa) | ||||
ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa) | ||||
RARA | Retinoic acid receptor alpha. (478 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa) | ||||
SLC22A13 | Solute carrier family 22 member 13. (551 aa) | ||||
STAT6 | Signal transducer and activator of transcription. (847 aa) | ||||
ZBTB1 | Zinc finger and BTB domain containing 1. (668 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) | ||||
NECTIN2 | Nectin cell adhesion molecule 2. (538 aa) | ||||
PANX1 | Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa) | ||||
ENSRROP00000016443 | Prohibitin. (112 aa) | ||||
LOC104676775 | Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa) | ||||
TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) | ||||
UNC13D | Unc-13 homolog D. (1133 aa) | ||||
DDX50 | DExD-box helicase 50. (737 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
ENSRROP00000015516 | Helicase C-terminal domain-containing protein. (319 aa) | ||||
KLRD1 | Killer cell lectin like receptor D1. (179 aa) | ||||
STXBP2 | Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (593 aa) | ||||
MBL2 | Mannose binding lectin 2. (255 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (616 aa) | ||||
C12orf4 | Chromosome 12 open reading frame 4. (552 aa) | ||||
DDX1 | DEAD-box helicase 1. (740 aa) | ||||
MAVS | CARD_2 domain-containing protein. (545 aa) | ||||
VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) | ||||
PLA2G5 | Phospholipase A(2). (138 aa) | ||||
MAD2L2 | Mitotic arrest deficient 2 like 2. (224 aa) | ||||
ENSRROP00000013117 | Prohibitin. (179 aa) | ||||
DDX60 | DExD/H-box helicase 60. (1712 aa) | ||||
CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) | ||||
PTPRJ | Protein tyrosine phosphatase receptor type J. (1337 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (787 aa) | ||||
TYROBP | TYRO protein tyrosine kinase binding protein. (123 aa) | ||||
PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (813 aa) | ||||
CD244 | CD244 molecule. (370 aa) | ||||
SCIMP | SLP adaptor and CSK interacting membrane protein. (141 aa) | ||||
LAG3 | Lymphocyte activating 3. (525 aa) | ||||
IL1R1 | Interleukin 1 receptor type 1. (569 aa) | ||||
COLEC11 | Collectin subfamily member 11. (304 aa) | ||||
MASP2 | Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa) | ||||
B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) | ||||
ARID5A | AT-rich interaction domain 5A. (594 aa) | ||||
CD84 | CD84 molecule. (339 aa) | ||||
SASH3 | SAM and SH3 domain containing 3. (380 aa) | ||||
DDX58 | DExD/H-box helicase 58. (925 aa) | ||||
MYO18A | Myosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2042 aa) | ||||
ANKRD17 | Ankyrin repeat domain 17. (2603 aa) | ||||
STX7 | Syntaxin 7; Belongs to the syntaxin family. (261 aa) | ||||
C17orf99 | Chromosome 17 open reading frame 99. (265 aa) | ||||
CCL19 | C-C motif chemokine. (98 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
LOC104675385 | AIG1-type G domain-containing protein. (323 aa) | ||||
FBXO38 | F-box protein 38. (1188 aa) | ||||
CD55 | CD55 molecule (Cromer blood group). (540 aa) | ||||
CD86 | CD86 molecule. (329 aa) | ||||
TFRC | Transferrin receptor. (760 aa) | ||||
LOC104675178 | MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (224 aa) | ||||
LOC104659533 | FAM35_C domain-containing protein. (233 aa) | ||||
RIF1 | Replication timing regulatory factor 1. (2471 aa) | ||||
ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1198 aa) | ||||
FCER2 | Fc fragment of IgE receptor II. (366 aa) | ||||
LBP | Lipopolysaccharide binding protein. (484 aa) | ||||
MZB1 | Marginal zone B and B1 cell specific protein. (188 aa) | ||||
SH2D1B | SH2 domain containing 1B. (132 aa) | ||||
LYN | Tyrosine-protein kinase. (491 aa) | ||||
RTN4 | Reticulon. (1138 aa) | ||||
IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) | ||||
IL12RB1 | Interleukin 12 receptor subunit beta 1. (661 aa) | ||||
PHB2 | Prohibitin. (299 aa) | ||||
RABGEF1 | Uncharacterized protein. (497 aa) | ||||
FOXF1 | Forkhead box F1. (379 aa) | ||||
ENSRROP00000006168 | IGc1 domain-containing protein; Belongs to the MHC class I family. (345 aa) | ||||
CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) | ||||
ENSRROP00000005569 | Uncharacterized protein. (601 aa) | ||||
FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) | ||||
COLEC10 | Collectin subfamily member 10. (277 aa) | ||||
KLK7 | Kallikrein related peptidase 7; Belongs to the peptidase S1 family. (253 aa) | ||||
ENSRROP00000005346 | Ig-like domain-containing protein; Belongs to the MHC class I family. (305 aa) | ||||
CD1E | CD1e molecule. (387 aa) | ||||
KIR3DL3 | Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (428 aa) | ||||
IL18R1 | Interleukin 18 receptor 1. (540 aa) | ||||
ENSRROP00000004259 | TNF receptor-associated factor. (466 aa) | ||||
TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) | ||||
FFAR2 | Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa) | ||||
APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa) | ||||
FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (356 aa) | ||||
SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
SNX4 | Sorting nexin 4. (450 aa) | ||||
ENSRROP00000002798 | Ig-like domain-containing protein; Belongs to the MHC class I family. (255 aa) | ||||
IL17F | Interleukin 17F. (163 aa) | ||||
DNAJB9 | DnaJ heat shock protein family (Hsp40) member B9. (222 aa) | ||||
NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) | ||||
LTA | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa) | ||||
ENSRROP00000002135 | A20-type domain-containing protein. (114 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1976 aa) | ||||
SHLD2 | FAM35_C domain-containing protein. (905 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) | ||||
TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) | ||||
MIF | Uncharacterized protein. (115 aa) | ||||
CD80 | CD80 molecule. (288 aa) | ||||
IL4R | Interleukin 4 receptor. (825 aa) | ||||
LOC104669987 | MHC_I-like_Ag-recog domain-containing protein. (146 aa) | ||||
CD1B | CD1b molecule. (333 aa) | ||||
IL6 | Interleukin 6. (214 aa) | ||||
HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (354 aa) | ||||
FCN2 | Ficolin 2. (313 aa) | ||||
IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
ENSRROP00000000939 | Ig-like domain-containing protein; Belongs to the MHC class I family. (364 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) | ||||
RSAD2 | Radical S-adenosyl methionine domain containing 2. (360 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) | ||||
FGR | Tyrosine-protein kinase. (529 aa) | ||||
LOC104670100 | Uncharacterized protein. (351 aa) | ||||
LAMP1 | Lysosomal associated membrane protein 1. (412 aa) | ||||
IL17A | Interleukin 17A. (155 aa) | ||||
BLK | Tyrosine-protein kinase. (505 aa) | ||||
PGC | Progastricsin; Belongs to the peptidase A1 family. (388 aa) | ||||
KIT | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa) | ||||
PAXIP1 | PAX interacting protein 1. (1075 aa) | ||||
ENSRROP00000034722 | Uncharacterized protein. (107 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) | ||||
ATAD5 | ATPase family AAA domain containing 5. (1834 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
SHB | SH2 domain containing adaptor protein B. (509 aa) | ||||
FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) | ||||
LOC104668623 | C-type lectin domain-containing protein. (246 aa) | ||||
KLRK1 | Killer cell lectin like receptor K1. (216 aa) | ||||
STX4 | Syntaxin 4; Belongs to the syntaxin family. (298 aa) | ||||
KLK5 | Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa) | ||||
SHLD1 | Shieldin complex subunit 1. (228 aa) | ||||
ANXA1 | Annexin. (346 aa) |