STRINGSTRING
NCR3 NCR3 CREBBP CREBBP SPG21 SPG21 ENSRROP00000000550 ENSRROP00000000550 ZNF683 ZNF683 FCN2 FCN2 IKBKG IKBKG BRAF BRAF KLHL6 KLHL6 MAP2K7 MAP2K7 BANK1 BANK1 MYO1G MYO1G LIME1 LIME1 FFAR2 FFAR2 ENSRROP00000004259 ENSRROP00000004259 MAPK8 MAPK8 STOML2 STOML2 IGHD IGHD COLEC10 COLEC10 FER FER LOC104653882 LOC104653882 PSEN1 PSEN1 STK11 STK11 PDE4B PDE4B LOC104665503 LOC104665503 NCKAP1L NCKAP1L LAX1 LAX1 THEMIS2 THEMIS2 PDE4D PDE4D PAK2 PAK2 LYN LYN LOC104671953 LOC104671953 BAX BAX MAPK9 MAPK9 FCHO1 FCHO1 EIF2B1 EIF2B1 CTLA4 CTLA4 LAT2 LAT2 PRKCE PRKCE CD24 CD24 MASP2 MASP2 COLEC11 COLEC11 ENSRROP00000011408 ENSRROP00000011408 PIK3CA PIK3CA PRKCD PRKCD BLNK BLNK PTPN22 PTPN22 INPP5D INPP5D TYROBP TYROBP PIK3CD PIK3CD PTPRJ PTPRJ LOC104664704 LOC104664704 CLEC12B CLEC12B CD38 CD38 CD3E CD3E VAV1 VAV1 LCK LCK RFTN1 RFTN1 SOS1 SOS1 VAV2 VAV2 LOC104675310 LOC104675310 LILRB4 LILRB4 SKAP1 SKAP1 MBL2 MBL2 KLRD1 KLRD1 ENSRROP00000015288 ENSRROP00000015288 BCAR1 BCAR1 CD276 CD276 ABL1 ABL1 MAP2K4 MAP2K4 BTN1A1 BTN1A1 ENSRROP00000017558 ENSRROP00000017558 THEMIS THEMIS YES1 YES1 TNFRSF21 TNFRSF21 CD79B CD79B FCN3 FCN3 FYN FYN CD247 CD247 SLA2 SLA2 ENSRROP00000019711 ENSRROP00000019711 BTK BTK HHLA2 HHLA2 NFKBIZ NFKBIZ SRC SRC FYB2 FYB2 CLEC6A CLEC6A PLEKHA1 PLEKHA1 SYK SYK ENSRROP00000020232 ENSRROP00000020232 VTCN1 VTCN1 MORN5 MORN5 PRKCB PRKCB TEC TEC PRAM1 PRAM1 DENND1B DENND1B THY1 THY1 OSCAR OSCAR C5AR1 C5AR1 GPLD1 GPLD1 SPPL3 SPPL3 PTPRC PTPRC PRKD2 PRKD2 VAV3 VAV3 PLA2G6 PLA2G6 GATA3 GATA3 MASP1 MASP1 PRKCQ PRKCQ LOC104668622 LOC104668622 MAP3K1 MAP3K1 ENSRROP00000024470 ENSRROP00000024470 ENSRROP00000024628 ENSRROP00000024628 MAPK1 MAPK1 PLCG1 PLCG1 HLA-DPB1 HLA-DPB1 IKBKB IKBKB CD40 CD40 RC3H1 RC3H1 LOC104664707 LOC104664707 ENSRROP00000025981 ENSRROP00000025981 ICOSLG ICOSLG LOC104678031 LOC104678031 ITK ITK CMKLR1 CMKLR1 LCP2 LCP2 CLEC4E CLEC4E PIGR PIGR FCAR FCAR ZC3H12A ZC3H12A EIF2B5 EIF2B5 PLPP4 PLPP4 EP300 EP300 LOC104680738 LOC104680738 RBCK1 RBCK1 MALT1 MALT1 MAPK10 MAPK10 PTPN6 PTPN6 CD8A CD8A ENSRROP00000029653 ENSRROP00000029653 BMX BMX FOXP3 FOXP3 UBE2N UBE2N WNK1 WNK1 CD79A CD79A EIF2B3 EIF2B3 TMEM269 TMEM269 LILRA1 LILRA1 BTNL9 BTNL9 ENSRROP00000032659 ENSRROP00000032659 PTK2 PTK2 LOC104673998 LOC104673998 FGR FGR FYB1 FYB1 LOC104670100 LOC104670100 HLA-DQB1 HLA-DQB1 BTN3A1 BTN3A1 LIMK1 LIMK1 BLK BLK MS4A2 MS4A2 KIT KIT ENSRROP00000034614 ENSRROP00000034614 ZAP70 ZAP70 SHB SHB BCL2 BCL2 MEF2C MEF2C CACNB3 CACNB3 LOC104668623 LOC104668623 LOC104655335 LOC104655335 HRAS HRAS KLRK1 KLRK1 ENSRROP00000036642 ENSRROP00000036642 ENSRROP00000037073 ENSRROP00000037073 KLRC1 KLRC1 ADA ADA CSK CSK PLD2 PLD2 EIF2B2 EIF2B2 TRAF6 TRAF6 MS4A1 MS4A1 NFATC2 NFATC2 LOC104662867 LOC104662867 KHDRBS1 KHDRBS1 CRKL CRKL ENSRROP00000040645 ENSRROP00000040645 CLEC4D CLEC4D CR2 CR2 CBLB CBLB RC3H2 RC3H2 CD28 CD28 EIF2B4 EIF2B4 NR4A3 NR4A3 FCER1G FCER1G CACNB4 CACNB4 TXK TXK BCL10 BCL10 ENSRROP00000043101 ENSRROP00000043101 RNF31 RNF31 BTNL8 BTNL8 ERMAP ERMAP PLCG2 PLCG2 PAK1 PAK1 LOC104663345 LOC104663345 BTLA BTLA BAG6 BAG6 NFKBID NFKBID RIPK2 RIPK2 NFAM1 NFAM1 CD19 CD19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCR3Natural cytotoxicity triggering receptor 3. (189 aa)
CREBBPCREB binding protein. (2442 aa)
SPG21SPG21 abhydrolase domain containing, maspardin. (308 aa)
ENSRROP00000000550Protein kinase domain-containing protein. (340 aa)
ZNF683Zinc finger protein 683. (524 aa)
FCN2Ficolin 2. (313 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (761 aa)
KLHL6Kelch like family member 6. (621 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (403 aa)
BANK1Uncharacterized protein. (346 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
LIME1Uncharacterized protein. (292 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
ENSRROP00000004259TNF receptor-associated factor. (466 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
STOML2Stomatin like 2. (356 aa)
IGHDImmunoglobulin heavy constant delta. (379 aa)
COLEC10Collectin subfamily member 10. (277 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
LOC104653882IGv domain-containing protein. (150 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
PDE4BPhosphodiesterase. (564 aa)
LOC104665503UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
LAX1Lymphocyte transmembrane adaptor 1. (398 aa)
THEMIS2Thymocyte selection associated family member 2. (644 aa)
PDE4DPhosphodiesterase. (585 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
LYNTyrosine-protein kinase. (491 aa)
LOC104671953Ig-like domain-containing protein. (332 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
FCHO1FCH domain only 1. (934 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (306 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
LAT2Linker for activation of T cells family member 2. (242 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CD24Uncharacterized protein. (127 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
COLEC11Collectin subfamily member 11. (304 aa)
ENSRROP00000011408RBD domain-containing protein. (482 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
BLNKB cell linker. (456 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1188 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (123 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1337 aa)
LOC104664704Ig-like domain-containing protein. (184 aa)
CLEC12BC-type lectin domain family 12 member B. (276 aa)
CD38CD38 molecule. (301 aa)
CD3ECD3e molecule. (198 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
LCKTyrosine-protein kinase. (561 aa)
RFTN1Raftlin, lipid raft linker 1. (578 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
VAV2Vav guanine nucleotide exchange factor 2. (810 aa)
LOC104675310Uncharacterized protein. (484 aa)
LILRB4Leukocyte immunoglobulin like receptor B4. (471 aa)
SKAP1Src kinase associated phosphoprotein 1. (397 aa)
MBL2Mannose binding lectin 2. (255 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
ENSRROP00000015288DH domain-containing protein. (263 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
CD276CD276 molecule. (496 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
BTN1A1Butyrophilin subfamily 1 member A1. (526 aa)
ENSRROP00000017558Uncharacterized protein. (78 aa)
THEMISThymocyte selection associated. (680 aa)
YES1Tyrosine-protein kinase. (543 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
CD79BCD79b molecule. (239 aa)
FCN3Ficolin 3. (320 aa)
FYNTyrosine-protein kinase. (537 aa)
CD247CD247 molecule. (173 aa)
SLA2Src like adaptor 2. (261 aa)
ENSRROP00000019711PDE4_UCR domain-containing protein. (158 aa)
BTKTyrosine-protein kinase. (690 aa)
HHLA2HERV-H LTR-associating 2. (419 aa)
NFKBIZNFKB inhibitor zeta. (723 aa)
SRCTyrosine-protein kinase. (540 aa)
FYB2FYN binding protein 2. (729 aa)
CLEC6AC-type lectin domain containing 6A. (209 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
SYKTyrosine-protein kinase. (635 aa)
ENSRROP00000020232Ig-like domain-containing protein. (151 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
MORN5MORN repeat containing 5. (175 aa)
PRKCBNon-specific serine/threonine protein kinase. (590 aa)
TECTyrosine-protein kinase. (630 aa)
PRAM1PML-RARA regulated adaptor molecule 1. (719 aa)
DENND1BDENN domain containing 1B. (775 aa)
THY1Thy-1 cell surface antigen. (161 aa)
OSCAROsteoclast associated Ig-like receptor. (269 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (841 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1311 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
VAV3Uncharacterized protein. (287 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
GATA3GATA binding protein 3. (444 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (739 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
LOC104668622C-type lectin domain-containing protein. (236 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1449 aa)
ENSRROP00000024470A_deaminase domain-containing protein. (344 aa)
ENSRROP00000024628Ig-like domain-containing protein. (351 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
CD40CD40 molecule. (278 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
LOC104664707Ig-like domain-containing protein. (118 aa)
ENSRROP00000025981UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
ICOSLGUncharacterized protein. (275 aa)
LOC104678031UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ITKTyrosine-protein kinase. (620 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
CLEC4EC-type lectin domain family 4 member E. (219 aa)
PIGRPolymeric immunoglobulin receptor. (764 aa)
FCARFc fragment of IgA receptor. (178 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (601 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
PLPP4Phospholipid phosphatase 4. (271 aa)
EP300E1A binding protein p300. (2413 aa)
LOC104680738UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
MALT1MALT1 paracaspase. (774 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
CD8ACD8a molecule. (235 aa)
ENSRROP00000029653Uncharacterized protein. (95 aa)
BMXTyrosine-protein kinase. (675 aa)
FOXP3Forkhead box P3. (454 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
WNK1WNK lysine deficient protein kinase 1. (2834 aa)
CD79ACD79a molecule. (225 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (452 aa)
TMEM269Transmembrane protein 269. (203 aa)
LILRA1Uncharacterized protein. (492 aa)
BTNL9Butyrophilin like 9. (529 aa)
ENSRROP00000032659Uncharacterized protein. (354 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1109 aa)
LOC104673998UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
FGRTyrosine-protein kinase. (529 aa)
FYB1FYN binding protein 1. (839 aa)
LOC104670100Uncharacterized protein. (351 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (281 aa)
BTN3A1Butyrophilin subfamily 3 member A1. (524 aa)
LIMK1LIM domain kinase 1. (677 aa)
BLKTyrosine-protein kinase. (505 aa)
MS4A2Membrane spanning 4-domains A2. (245 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa)
ENSRROP00000034614Tyrosine-protein kinase. (465 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
MEF2CMyocyte enhancer factor 2C. (466 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (485 aa)
LOC104668623C-type lectin domain-containing protein. (246 aa)
LOC104655335Uncharacterized protein. (511 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
KLRK1Killer cell lectin like receptor K1. (216 aa)
ENSRROP00000036642Phorbol-ester/DAG-type domain-containing protein. (57 aa)
ENSRROP00000037073Uncharacterized protein. (522 aa)
KLRC1Killer cell lectin like receptor C1. (233 aa)
ADAA_deaminase domain-containing protein. (443 aa)
CSKTyrosine-protein kinase. (450 aa)
PLD2Phospholipase. (933 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
NFATC2Nuclear factor of activated T cells 2. (932 aa)
LOC104662867UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (547 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ENSRROP00000040645Ig-like domain-containing protein. (145 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
CR2Complement C3d receptor 2. (1093 aa)
CBLBCbl proto-oncogene B. (982 aa)
RC3H2Ring finger and CCCH-type domains 2. (1229 aa)
CD28CD28 molecule. (220 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
FCER1GFc fragment of IgE receptor Ig. (112 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
TXKTyrosine-protein kinase. (527 aa)
BCL10BCL10 immune signaling adaptor. (316 aa)
ENSRROP00000043101Ig-like domain-containing protein. (244 aa)
RNF31Uncharacterized protein. (1072 aa)
BTNL8Butyrophilin like 8. (307 aa)
ERMAPErythroblast membrane associated protein (Scianna blood group). (475 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
LOC104663345Uncharacterized protein. (518 aa)
BTLAB and T lymphocyte associated. (289 aa)
BAG6BCL2 associated athanogene 6. (1129 aa)
NFKBIDNFKB inhibitor delta. (469 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
NFAM1NFAT activating protein with ITAM motif 1. (271 aa)
CD19CD19 molecule. (558 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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