STRINGSTRING
ENSRROP00000044073 ENSRROP00000044073 ENSRROP00000027580 ENSRROP00000027580 MCM7 MCM7 BLM BLM MCM6 MCM6 RTEL1 RTEL1 DQX1 DQX1 ERCC2 ERCC2 SETX SETX ERCC3 ERCC3 RECQL4 RECQL4 UPF1 UPF1 MCM9 MCM9 CHD2 CHD2 CHD5 CHD5 CHD1L CHD1L CHD6 CHD6 RAD54L2 RAD54L2 MCM2 MCM2 CHD4 CHD4 ERCC6L ERCC6L ENSRROP00000039005 ENSRROP00000039005 DDX11 DDX11 RECQL5 RECQL5 CHD8 CHD8 DHX9 DHX9 RUVBL1 RUVBL1 HELQ HELQ MCM3 MCM3 POLQ POLQ C17orf64 C17orf64 WRN WRN ASCC3 ASCC3 HFM1 HFM1 IGHMBP2 IGHMBP2 MCM8 MCM8 ATRX ATRX FANCM FANCM RAD54L RAD54L RECQL RECQL ENSRROP00000002311 ENSRROP00000002311 CHD7 CHD7 RAD51 RAD51 CHD1 CHD1 SUPV3L1 SUPV3L1 FBH1 FBH1 CHD3 CHD3 G3BP1 G3BP1 RUVBL2 RUVBL2 XRCC6 XRCC6 WRNIP1 WRNIP1 BRIP1 BRIP1 PIF1 PIF1 GTF2F2 GTF2F2 XRCC5 XRCC5 MCM4 MCM4 DNA2 DNA2 LOC104659451 LOC104659451 CHD9 CHD9 TWNK TWNK MCM5 MCM5 SMARCAD1 SMARCAD1 HELB HELB TM4SF19 TM4SF19 NAV2 NAV2 DHX36 DHX36 ENSRROP00000026157 ENSRROP00000026157
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRROP00000044073Uncharacterized protein. (366 aa)
ENSRROP00000027580Uncharacterized protein. (220 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (626 aa)
BLMBLM RecQ like helicase. (1416 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1299 aa)
DQX1DEAQ-box RNA dependent ATPase 1. (717 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
SETXSenataxin. (2678 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
RECQL4RecQ like helicase 4. (1150 aa)
UPF1UPF1 RNA helicase and ATPase. (1079 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa)
CHD2Uncharacterized protein. (1828 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1968 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (888 aa)
CHD6Chromodomain helicase DNA binding protein 6. (1457 aa)
RAD54L2RAD54 like 2. (1467 aa)
MCM2DNA helicase; Belongs to the MCM family. (907 aa)
CHD4Uncharacterized protein. (1913 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1252 aa)
ENSRROP00000039005Uncharacterized protein. (450 aa)
DDX11DEAD/H-box helicase 11. (905 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2582 aa)
DHX9DExH-box helicase 9. (1275 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
HELQHelicase, POLQ like. (1101 aa)
MCM3DNA helicase; Belongs to the MCM family. (828 aa)
POLQDNA polymerase theta. (2716 aa)
C17orf64Chromosome 17 open reading frame 64. (236 aa)
WRNWRN RecQ like helicase. (1431 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2202 aa)
HFM1Helicase for meiosis 1. (1435 aa)
IGHMBP2Immunoglobulin mu DNA binding protein 2. (986 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (867 aa)
ATRXUncharacterized protein. (164 aa)
FANCMFA complementation group M. (2050 aa)
RAD54LRAD54 like. (747 aa)
RECQLATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa)
ENSRROP00000002311Ku domain-containing protein. (539 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1712 aa)
SUPV3L1Suv3 like RNA helicase. (787 aa)
FBH1F-box DNA helicase 1. (1079 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2014 aa)
G3BP1G3BP stress granule assembly factor 1. (466 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
XRCC6X-ray repair cross complementing 6. (617 aa)
WRNIP1WRN helicase interacting protein 1. (665 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1249 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (703 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
DNA2DNA replication helicase/nuclease 2. (1061 aa)
LOC104659451Uncharacterized protein. (99 aa)
CHD9Uncharacterized protein. (2395 aa)
TWNKTwinkle mtDNA helicase. (684 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
SMARCAD1Uncharacterized protein. (1026 aa)
HELBDNA helicase B. (1087 aa)
TM4SF19Uncharacterized protein. (295 aa)
NAV2Neuron navigator 2. (2432 aa)
DHX36DEAH-box helicase 36. (1008 aa)
ENSRROP00000026157HELICc2 domain-containing protein. (116 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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