STRINGSTRING
ARRB1 ARRB1 GNAS GNAS SOCS1 SOCS1 IGF2 IGF2 SHC1 SHC1 PIK3R1 PIK3R1 CRK CRK IGF1 IGF1 INSR INSR LOC104663799 LOC104663799 YWHAH YWHAH SOCS2 SOCS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARRB1Arrestin beta 1. (473 aa)
GNASGNAS complex locus. (1041 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
IGF2Insulin like growth factor 2. (236 aa)
SHC1SHC adaptor protein 1. (574 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (208 aa)
INSRTyrosine-protein kinase receptor. (1370 aa)
LOC104663799Uncharacterized protein. (246 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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