STRINGSTRING
ENSRROP00000005618 ENSRROP00000005618 TBP TBP MED27 MED27 MED21 MED21 MED18 MED18 ENSRROP00000024732 ENSRROP00000024732 GTF2A1 GTF2A1 MED29 MED29 MED19 MED19 DR1 DR1 MED22 MED22 MED31 MED31 TAF7L TAF7L CCNH CCNH MED23 MED23 POLR2G POLR2G MED15 MED15 LOC104669754 LOC104669754 ENSRROP00000018014 ENSRROP00000018014 ENSRROP00000017569 ENSRROP00000017569 MED28 MED28 GTF2F2 GTF2F2 TAF1 TAF1 ELOC ELOC MED16 MED16 ENSRROP00000013523 ENSRROP00000013523 MED26 MED26 TAF4B TAF4B E2F2 E2F2 MED30 MED30 MED8 MED8 MED25 MED25 LOC104657870 LOC104657870 MAZ MAZ TAF12 TAF12 LOC104674456 LOC104674456 MED7 MED7 GTF2B GTF2B TAF3 TAF3 MED4 MED4 GTF2E1 GTF2E1 POLR2D POLR2D GTF2F1 GTF2F1 LOC104674542 LOC104674542 ENSRROP00000004459 ENSRROP00000004459 E2F3 E2F3 ELOA ELOA STON1 STON1 TAF8 TAF8 LOC104655794 LOC104655794 MED14 MED14 GTF2H5 GTF2H5 TAF5 TAF5 CDK7 CDK7 ERCC3 ERCC3 CDK9 CDK9 PPARGC1A PPARGC1A TAF11 TAF11 TAF6L TAF6L TAF6 TAF6 MED24 MED24 ENSRROP00000036712 ENSRROP00000036712 ENSRROP00000037280 ENSRROP00000037280 GTF2A2 GTF2A2 TAF2 TAF2 GTF2E2 GTF2E2 MED9 MED9 POLR2I POLR2I ENSRROP00000039400 ENSRROP00000039400 TAF4 TAF4 TAF10 TAF10 MED11 MED11 ENSRROP00000045588 ENSRROP00000045588
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRROP00000005618Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (105 aa)
TBPTATA-box binding protein. (333 aa)
MED27Mediator complex subunit 27. (311 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (159 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
ENSRROP00000024732Uncharacterized protein. (252 aa)
GTF2A1General transcription factor IIA subunit 1. (370 aa)
MED29Mediator complex subunit 29. (221 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
DR1Down-regulator of transcription 1. (176 aa)
MED22Mediator complex subunit 22. (200 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
TAF7LTATA-box binding protein associated factor 7 like. (463 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
MED23Mediator complex subunit 23. (1374 aa)
POLR2GRNA polymerase II subunit G. (255 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (784 aa)
LOC104669754Uncharacterized protein. (124 aa)
ENSRROP00000018014Protein kinase domain-containing protein. (315 aa)
ENSRROP00000017569Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (442 aa)
MED28Mediator complex subunit 28. (216 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
TAF1TATA-box binding protein associated factor 1. (1196 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (877 aa)
ENSRROP00000013523TAFII28 domain-containing protein. (210 aa)
MED26TFIIS N-terminal domain-containing protein. (600 aa)
TAF4BTATA-box binding protein associated factor 4b. (862 aa)
E2F2E2F transcription factor 2. (437 aa)
MED30Mediator complex subunit 30. (178 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (338 aa)
MED25Mediator complex subunit 25. (747 aa)
LOC104657870Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
MAZMYC associated zinc finger protein. (264 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
LOC104674456Ubiquitin-like domain-containing protein. (118 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
TAF3TATA-box binding protein associated factor 3. (931 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (545 aa)
LOC104674542Uncharacterized protein. (264 aa)
ENSRROP00000004459Skp1_POZ domain-containing protein. (93 aa)
E2F3E2F transcription factor 3. (465 aa)
ELOAElongin A. (839 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (1182 aa)
TAF8TATA-box binding protein associated factor 8. (311 aa)
LOC104655794Transcription initiation factor TFIID subunit 13. (124 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
TAF6LTATA-box binding protein associated factor 6 like. (622 aa)
TAF6TATA-box binding protein associated factor 6. (738 aa)
MED24Mediator complex subunit 24. (1008 aa)
ENSRROP00000036712TFIIA_gamma_C domain-containing protein. (74 aa)
ENSRROP00000037280Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (104 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
TAF2TATA-box binding protein associated factor 2. (1251 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (289 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ENSRROP00000039400Uncharacterized protein; Belongs to the SKP1 family. (100 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
ENSRROP00000045588Ubiquitin-like domain-containing protein. (137 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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