128 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNAQ	G protein subunit alpha q. (359 aa)
	ADRA1A	Adrenoceptor alpha 1A. (455 aa)
	ADRA1D	Adrenoceptor alpha 1D. (529 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
	GHRH	Growth hormone releasing hormone. (107 aa)
	LOC104663799	Uncharacterized protein. (246 aa)
	ADM5	Adrenomedullin 5 (putative). (145 aa)
	ADM2	Adrenomedullin 2. (148 aa)
	ADGRG3	Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (551 aa)
	GNAS	GNAS complex locus. (1041 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1383 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1. (176 aa)
	TUBB3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the tubulin family. (791 aa)
	ADCY6	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa)
	GALR2	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	TBXA2R	Thromboxane A2 receptor. (384 aa)
	RAMP2	Receptor activity modifying protein 2. (175 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (489 aa)
	AKAP13	A-kinase anchoring protein 13. (2874 aa)
	GPR157	G protein-coupled receptor 157. (335 aa)
	RAMP3	Receptor activity modifying protein 3. (151 aa)
	CALCRL	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (458 aa)
	ADGRG1	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (687 aa)
	ADGRL3	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (647 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	S1PR3	Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa)
	ENSRROP00000001260	Latrophilin domain-containing protein. (184 aa)
	MC3R	Melanocortin 3 receptor. (323 aa)
	S1PR1	Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	S1PR2	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	CHRM1	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
	GPR12	G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa)
	ADRB3	G_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
	CNR2	Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	CALCB	Calcitonin related polypeptide beta. (127 aa)
	GALR1	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
	GPR65	G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (337 aa)
	CXCL10	C-X-C motif chemokine. (98 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
	ADCY5	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
	GPR3	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa)
	PTGER2	Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	ADRA2B	Adrenoceptor alpha 2B. (448 aa)
	GPR4	G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	GPR119	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (1011 aa)
	ADRB2	Adrenoceptor beta 2. (415 aa)
	ENSRROP00000005987	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	PLN	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
	PDE4D	Phosphodiesterase. (585 aa)
	GNA13	G protein subunit alpha 13. (308 aa)
	MC4R	Melanocortin 4 receptor. (332 aa)
	ADORA2A	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
	ADGRB1	Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1508 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	ADGRG4	Adhesion G protein-coupled receptor G4; Belongs to the G-protein coupled receptor 2 family. (3082 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (357 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
	PTRHD1	Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	GIP	Gastric inhibitory polypeptide. (153 aa)
	GPHB5	Glycoprotein hormone subunit beta 5. (130 aa)
	ENSRROP00000011088	G_PROTEIN_RECEP_F1_2 domain-containing protein. (349 aa)
	ADGRF1	Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (908 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1685 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
	ADGRG6	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1249 aa)
	GIPR	Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
	ADGRE3	Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (652 aa)
	CRHR1	Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
	PTGFR	Prostaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	GPHA2	Glycoprotein hormone subunit alpha 2. (127 aa)
	ADGRG5	Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family. (533 aa)
	ADGRG2	Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. (868 aa)
	PF4	C-X-C motif chemokine. (101 aa)
	GNAL	G protein subunit alpha L. (448 aa)
	ADORA2B	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
	ADRA1B	Adrenoceptor alpha 1B. (512 aa)
	GPR78	G protein-coupled receptor 78. (363 aa)
	LPAR1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	ENSRROP00000019711	PDE4_UCR domain-containing protein. (158 aa)
	GPR26	G protein-coupled receptor 26. (337 aa)
	PTGER4	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	ADGRD2	Adhesion G protein-coupled receptor D2; Belongs to the G-protein coupled receptor 2 family. (953 aa)
	ADGRG7	Adhesion G protein-coupled receptor G7; Belongs to the G-protein coupled receptor 2 family. (797 aa)
	ADGRE2	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (816 aa)
	ADGRF2	Adhesion G protein-coupled receptor F2; Belongs to the G-protein coupled receptor 2 family. (692 aa)
	VIP	Vasoactive intestinal peptide. (170 aa)
	CNR1	Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (439 aa)
	LPAR3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	PTHLH	Parathyroid hormone like hormone. (209 aa)
	CXCL9	C-X-C motif chemokine ligand 9. (120 aa)
	PTGER1	Prostaglandin E receptor 1. (402 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (341 aa)
	PTGIR	Prostaglandin I2 receptor. (386 aa)
	ADGRD1	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (906 aa)
	ADGRF4	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (751 aa)
	ADGRL4	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (614 aa)
	ADGRE5	Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (835 aa)
	ADGRL2	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1482 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
	RXFP2	Relaxin family peptide receptor 2. (748 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	ADGRF3	Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family. (1068 aa)
	PTH1R	Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
	CALCA	Calcitonin related polypeptide alpha. (140 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2261 aa)
	TMEM116	Transmembrane protein 116. (337 aa)
	RAMP1	Receptor activity modifying protein 1. (148 aa)
	ADGRB3	Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
	PTGER3	Prostaglandin E receptor 3. (414 aa)
	GPR161	G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (550 aa)
	CXCL11	C-X-C motif chemokine. (94 aa)
	ADM	Adrenomedullin. (184 aa)
	CHGA	Chromogranin A. (453 aa)
	RIT2	Ras like without CAAX 2. (217 aa)
	GCG	Glucagon. (180 aa)
	TCP11	T-complex 11. (516 aa)
	LOC104658087	Uncharacterized protein. (629 aa)
	IAPP	Islet amyloid polypeptide. (86 aa)
	ADGRL1	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1505 aa)
	GCGR	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (484 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSRROP00000009828	ENSRROP00000012552	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.485
ADCY1	ADCY3	ENSRROP00000009828	ENSRROP00000040934	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.945
ADCY1	ADCY4	ENSRROP00000009828	ENSRROP00000001096	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.473
ADCY1	ADCY5	ENSRROP00000009828	ENSRROP00000003576	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.455
ADCY1	ADCY6	ENSRROP00000009828	ENSRROP00000040839	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.454
ADCY1	ADCY7	ENSRROP00000009828	ENSRROP00000036529	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.515
ADCY1	ADCY8	ENSRROP00000009828	ENSRROP00000000304	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.956
ADCY1	ADCY9	ENSRROP00000009828	ENSRROP00000026575	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.663
ADCY1	ADRA2B	ENSRROP00000009828	ENSRROP00000004390	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adrenoceptor alpha 2B.	0.557
ADCY1	GNAL	ENSRROP00000009828	ENSRROP00000018429	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.968
ADCY1	GNAS	ENSRROP00000009828	ENSRROP00000038847	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.972
ADCY1	GNG2	ENSRROP00000009828	ENSRROP00000003513	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.554
ADCY1	LOC104663799	ENSRROP00000009828	ENSRROP00000037956	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.903
ADCY1	PDE4D	ENSRROP00000009828	ENSRROP00000006602	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.717
ADCY1	PTRHD1	ENSRROP00000009828	ENSRROP00000010447	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Peptidyl-tRNA hydrolase domain containing 1.	0.479
ADCY1	RAPGEF4	ENSRROP00000009828	ENSRROP00000005752	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Rap guanine nucleotide exchange factor 4.	0.918
ADCY2	ADCY1	ENSRROP00000012552	ENSRROP00000009828	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.485
ADCY2	ADCY4	ENSRROP00000012552	ENSRROP00000001096	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.442
ADCY2	ADCY5	ENSRROP00000012552	ENSRROP00000003576	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.762
ADCY2	ADCY6	ENSRROP00000012552	ENSRROP00000040839	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.752