45 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CSF2	Colony stimulating factor 2. (144 aa)
	CLCF1	Cardiotrophin like cytokine factor 1. (319 aa)
	STAT4	Signal transducer and activator of transcription. (748 aa)
	SOCS2	Suppressor of cytokine signaling 2. (198 aa)
	LOC104676158	Uncharacterized protein. (200 aa)
	IFNL1	Interferon lambda 1. (202 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	IL21	Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
	PTK6	Tyrosine-protein kinase. (451 aa)
	SOCS1	Suppressor of cytokine signaling 1. (215 aa)
	STAT5A	Signal transducer and activator of transcription. (905 aa)
	NEUROD1	Neurogenic differentiation factor. (356 aa)
	SOCS5	Suppressor of cytokine signaling 5. (536 aa)
	JAK3	Tyrosine-protein kinase. (1124 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1196 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	SOCS3	Suppressor of cytokine signaling 3. (225 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
	LOC104676156	Uncharacterized protein. (200 aa)
	PIAS1	Protein inhibitor of activated STAT 1. (653 aa)
	NMI	N-myc and STAT interactor. (307 aa)
	JAK2	Tyrosine-protein kinase. (1094 aa)
	STAT5B	Signal transducer and activator of transcription. (787 aa)
	CNTF	Ciliary neurotrophic factor. (200 aa)
	HAMP	Hepcidin antimicrobial peptide. (84 aa)
	IL31RA	Interleukin 31 receptor A. (748 aa)
	JAK1	Tyrosine-protein kinase. (1154 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (969 aa)
	STAT2	Signal transducer and activator of transcription. (859 aa)
	CSF2RB	Colony stimulating factor 2 receptor beta common subunit. (897 aa)
	IFNL4	Interferon lambda 4 (gene/pseudogene). (189 aa)
	STAT6	Signal transducer and activator of transcription. (847 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	STAT3	Signal transducer and activator of transcription. (802 aa)
	IFNAR2	Uncharacterized protein. (516 aa)
	IFNAR1	Interferon alpha and beta receptor subunit 1. (558 aa)
	PKD1	Polycystin 1, transient receptor potential channel interacting. (4297 aa)
	CTR9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
	STAMBP	STAM binding protein. (461 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	HPX	Hemopexin. (422 aa)
	STAT1	Signal transducer and activator of transcription. (787 aa)
	CSF2RA	Colony stimulating factor 2 receptor alpha subunit. (402 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	JAK2	ENSRROP00000024200	ENSRROP00000011033	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.407
CAV1	JAK3	ENSRROP00000024200	ENSRROP00000004608	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.407
CAV1	STAT3	ENSRROP00000024200	ENSRROP00000018412	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Signal transducer and activator of transcription.	0.434
CLCF1	CNTF	ENSRROP00000045172	ENSRROP00000012578	Cardiotrophin like cytokine factor 1.	Ciliary neurotrophic factor.	0.801
CLCF1	PRLR	ENSRROP00000045172	ENSRROP00000008452	Cardiotrophin like cytokine factor 1.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.776
CNTF	CLCF1	ENSRROP00000012578	ENSRROP00000045172	Ciliary neurotrophic factor.	Cardiotrophin like cytokine factor 1.	0.801
CNTF	CSF2RA	ENSRROP00000012578	ENSRROP00000035759	Ciliary neurotrophic factor.	Colony stimulating factor 2 receptor alpha subunit.	0.674
CNTF	CSF2RB	ENSRROP00000012578	ENSRROP00000014471	Ciliary neurotrophic factor.	Colony stimulating factor 2 receptor beta common subunit.	0.650
CNTF	IFNAR1	ENSRROP00000012578	ENSRROP00000019718	Ciliary neurotrophic factor.	Interferon alpha and beta receptor subunit 1.	0.650
CNTF	IFNAR2	ENSRROP00000012578	ENSRROP00000019471	Ciliary neurotrophic factor.	Uncharacterized protein.	0.650
CNTF	JAK2	ENSRROP00000012578	ENSRROP00000011033	Ciliary neurotrophic factor.	Tyrosine-protein kinase.	0.431
CNTF	JAK3	ENSRROP00000012578	ENSRROP00000004608	Ciliary neurotrophic factor.	Tyrosine-protein kinase.	0.431
CNTF	LEP	ENSRROP00000012578	ENSRROP00000018370	Ciliary neurotrophic factor.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.930
CNTF	LIF	ENSRROP00000012578	ENSRROP00000000246	Ciliary neurotrophic factor.	LIF interleukin 6 family cytokine.	0.597
CNTF	PRLR	ENSRROP00000012578	ENSRROP00000008452	Ciliary neurotrophic factor.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.796
CNTF	STAT3	ENSRROP00000012578	ENSRROP00000018412	Ciliary neurotrophic factor.	Signal transducer and activator of transcription.	0.568
CSF2	CSF2RA	ENSRROP00000037303	ENSRROP00000035759	Colony stimulating factor 2.	Colony stimulating factor 2 receptor alpha subunit.	0.998
CSF2	CSF2RB	ENSRROP00000037303	ENSRROP00000014471	Colony stimulating factor 2.	Colony stimulating factor 2 receptor beta common subunit.	0.996
CSF2	IFNAR1	ENSRROP00000037303	ENSRROP00000019718	Colony stimulating factor 2.	Interferon alpha and beta receptor subunit 1.	0.706
CSF2	IFNAR2	ENSRROP00000037303	ENSRROP00000019471	Colony stimulating factor 2.	Uncharacterized protein.	0.674