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| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa) |
| | PASD1 | PAS domain containing repressor 1. (687 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (309 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (951 aa) |
| | TH | Tyrosine hydroxylase. (532 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | HCRTR2 | Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa) |
| | KDM2A | Lysine demethylase 2A. (1162 aa) |
| | GPR157 | G protein-coupled receptor 157. (335 aa) |
| | ZPBP2 | Zona pellucida binding protein 2. (337 aa) |
| | NAGLU | N-acetyl-alpha-glucosaminidase. (743 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa) |
| | RORA | RAR related orphan receptor A. (555 aa) |
| | AGRP | Agouti related neuropeptide. (132 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) |
| | PROKR2 | Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa) |
| | PER3 | Period circadian regulator 3. (1178 aa) |
| | KDM5A | Lysine demethylase 5A. (1690 aa) |
| | MTNR1A | Melatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa) |
| | NONO | Non-POU domain containing octamer binding. (471 aa) |
| | ENSRROP00000039638 | Endo/exonuclease/phosphatase domain-containing protein. (403 aa) |
| | NR0B2 | Nuclear receptor subfamily 0 group B member 2. (257 aa) |
| | C3orf70 | Chromosome 3 open reading frame 70. (250 aa) |
| | KCNH7 | Potassium voltage-gated channel subfamily H member 7. (1196 aa) |
| | CSNK1D | Casein kinase 1 delta. (406 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (806 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (635 aa) |
| | CARTPT | CART prepropeptide. (116 aa) |
| | ID4 | Inhibitor of DNA binding 4, HLH protein. (153 aa) |
| | NUDT12 | Nudix hydrolase 12. (462 aa) |
| | AANAT | Aralkylamine N-acetyltransferase. (204 aa) |
| | RORC | RAR related orphan receptor C. (519 aa) |
| | TPH1 | Tryptophan hydroxylase 1. (444 aa) |
| | SETX | Senataxin. (2678 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1475 aa) |
| | MAGED1 | MAGE family member D1. (834 aa) |
| | GFPT1 | Glutamine--fructose-6-phosphate transaminase 1. (699 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (595 aa) |
| | TYMS | Thymidylate synthetase. (313 aa) |
| | ENSRROP00000019132 | Uncharacterized protein. (340 aa) |
| | ENSRROP00000019405 | Hist_deacetyl domain-containing protein. (352 aa) |
| | SIRT1 | Sirtuin 1. (746 aa) |
| | ENSRROP00000032935 | BZIP domain-containing protein. (148 aa) |
| | CSNK1E | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | ENSRROP00000032603 | Uncharacterized protein. (299 aa) |
| | ZFHX3 | Zinc finger homeobox 3. (3704 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2440 aa) |
| | BHLHE40 | Basic helix-loop-helix family member e40. (412 aa) |
| | MYBBP1A | MYB binding protein 1a. (1340 aa) |
| | ENSRROP00000030966 | Uncharacterized protein. (103 aa) |
| | ENSRROP00000030430 | Uncharacterized protein. (297 aa) |
| | NDUFA9 | NADH:ubiquinone oxidoreductase subunit A9. (377 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (586 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (499 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | CLOCK | Clock circadian regulator. (847 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (626 aa) |
| | NPAS2 | Neuronal PAS domain protein 2. (824 aa) |
| | LOC104663113 | Uncharacterized protein. (392 aa) |
| | NMS | Neuromedin S. (153 aa) |
| | ENSRROP00000026108 | Uncharacterized protein. (358 aa) |
| | RPE65 | Retinoid isomerohydrolase RPE65. (537 aa) |
| | RAI1 | Retinoic acid induced 1. (1910 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (373 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1177 aa) |
| | PROK2 | Prokineticin 2. (164 aa) |
| | LOC104677352 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa) |
| | DDC | Dopa decarboxylase. (494 aa) |
| | EP300 | E1A binding protein p300. (2413 aa) |
| | BHLHE41 | Uncharacterized protein. (334 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | HEBP1 | Heme binding protein 1. (189 aa) |
| | RBM4B | RNA binding motif protein 4B. (359 aa) |
| | RBM4 | Uncharacterized protein. (193 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | PER1 | Period circadian regulator 1. (1292 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | NOCT | Endo/exonuclease/phosphatase domain-containing protein. (431 aa) |
| | DBP | D-box binding PAR bZIP transcription factor. (317 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (398 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (614 aa) |
| | MTTP | Microsomal triglyceride transfer protein. (894 aa) |
| | CIART | Circadian associated repressor of transcription. (385 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (541 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) |
| | MYCBP2 | MYC binding protein 2. (4751 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | PER2 | Period circadian regulator 2. (1253 aa) |
| | HTR7 | 5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (479 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | HUWE1 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4423 aa) |
| | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator like 2. (622 aa) |
| | HOMER1 | Homer scaffold protein 1. (367 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | BTBD9 | BTB domain containing 9. (612 aa) |
| | TIMELESS | Timeless circadian regulator. (1292 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | NR1D2 | Nuclear receptor subfamily 1 group D member 2. (578 aa) |
| | GPR176 | G protein-coupled receptor 176. (515 aa) |
| | LOC104665044 | Uncharacterized protein. (455 aa) |
| | THRAP3 | Thyroid hormone receptor associated protein 3. (955 aa) |
| | ENSRROP00000008157 | Uncharacterized protein. (413 aa) |
| | ENSRROP00000007768 | Uncharacterized protein. (371 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | NRIP1 | Nuclear receptor interacting protein 1. (1155 aa) |
| | ENSRROP00000007230 | Uncharacterized protein. (193 aa) |
| | KDM8 | Lysine demethylase 8. (454 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | ID3 | Inhibitor of DNA binding 3, HLH protein. (119 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (613 aa) |
| | ENSRROP00000005654 | Uncharacterized protein. (103 aa) |
| | ENSRROP00000005469 | Uncharacterized protein. (53 aa) |
| | ASS1 | Uncharacterized protein. (412 aa) |
| | MTA1 | Metastasis associated 1. (697 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | PAX4 | Paired box 4. (351 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa) |
| | KLF10 | Kruppel like factor 10. (480 aa) |
| | CAVIN3 | Caveolae associated protein 3. (293 aa) |
| | HNRNPD | Heterogeneous nuclear ribonucleoprotein D. (355 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | MC3R | Melanocortin 3 receptor. (323 aa) |
| | ID2 | Inhibitor of DNA binding 2. (134 aa) |
| | ENSRROP00000001202 | RRM domain-containing protein. (172 aa) |
| | ATOH7 | Atonal bHLH transcription factor 7. (152 aa) |
