STRINGSTRING
FURIN FURIN LRTM1 LRTM1 LTBP2 LTBP2 LRTM2 LRTM2 ENSRROP00000024048 ENSRROP00000024048 COL11A1 COL11A1 NAV2 NAV2 BOC BOC LGR6 LGR6 RSPO4 RSPO4 TENM1 TENM1 COL5A1 COL5A1 RSPO3 RSPO3 CXCL6 CXCL6 PTPRC PTPRC LIPC LIPC FN1 FN1 RTN4R RTN4R APOB APOB ENSRROP00000019340 ENSRROP00000019340 FGF1 FGF1 ADAMTS3 ADAMTS3 TGFBR3 TGFBR3 COLQ COLQ LXN LXN CCN3 CCN3 CRISPLD1 CRISPLD1 CCL8 CCL8 FGF12 FGF12 ENSRROP00000013321 ENSRROP00000013321 LOC104655869 LOC104655869 CCN5 CCN5 CCDC80 CCDC80 HBEGF HBEGF THBS3 THBS3 SLIT3 SLIT3 APOE APOE LTF LTF FBLN7 FBLN7 PRSS57 PRSS57 C6orf15 C6orf15 CCN1 CCN1 ENSRROP00000008638 ENSRROP00000008638 ELANE ELANE REG4 REG4 FGF4 FGF4 LRRC70 LRRC70 LOC104676447 LOC104676447 ALK ALK SMOC1 SMOC1 FGFRL1 FGFRL1 RSPO2 RSPO2 SOD3 SOD3 FGF10 FGF10 RTN4RL1 RTN4RL1 COL13A1 COL13A1 PTN PTN ANGPTL3 ANGPTL3 FSTL1 FSTL1 CXCL10 CXCL10 ENSRROP00000002567 ENSRROP00000002567 BMP7 BMP7 MSTN MSTN LRPAP1 LRPAP1 MPO MPO VEGFB VEGFB F11 F11 PTCH1 PTCH1 LRRC3 LRRC3 FGF9 FGF9 FGFR2 FGFR2 IMPG2 IMPG2 CDON CDON LIPG LIPG ENSRROP00000016893 ENSRROP00000016893 LOC104667644 LOC104667644 SERPINA5 SERPINA5 ADAMTSL5 ADAMTSL5 AAMP AAMP KNG1 KNG1 LRRC3C LRRC3C FGF7 FGF7 PF4 PF4 HRG HRG ADA2 ADA2 NDNF NDNF EFEMP2 EFEMP2 BSPH1 BSPH1 PTPRS PTPRS LAMC2 LAMC2 TWSG1 TWSG1 ADGRG1 ADGRG1 ADAMTS5 ADAMTS5 CXCL8 CXCL8 CCN2 CCN2 LIPH LIPH THBS1 THBS1 SOST SOST CCN4 CCN4 VEGFA VEGFA CEL CEL COMP COMP AZU1 AZU1 SERPINA10 SERPINA10 RPL22 RPL22 TMEM184A TMEM184A FGF14 FGF14 GPNMB GPNMB SLIT1 SLIT1 MPIG6B MPIG6B COL5A3 COL5A3 CXCL13 CXCL13 CLEC3B CLEC3B SELP SELP FGFR4 FGFR4 ENSRROP00000038268 ENSRROP00000038268 LOC104667643 LOC104667643 ELSPBP1 ELSPBP1 AOC1 AOC1 FGF2 FGF2 SFRP1 SFRP1 APLP1 APLP1 ADAMTS8 ADAMTS8 BMP4 BMP4 LPL LPL RSPO1 RSPO1 LOC104678227 LOC104678227 HSD17B12 HSD17B12 LOC104675518 LOC104675518 THBS4 THBS4 ADAMTS1 ADAMTS1 CCN6 CCN6 APOA5 APOA5 SERPIND1 SERPIND1 APLP2 APLP2 ENSRROP00000034894 ENSRROP00000034894 NRP2 NRP2 PCOLCE2 PCOLCE2 SERPINE2 SERPINE2 TNXB TNXB APOH APOH TMEM184B TMEM184B ABI3BP ABI3BP PLA2G2D PLA2G2D APP APP COL25A1 COL25A1 CXCL11 CXCL11 PTPRF PTPRF MDK MDK ECM2 ECM2 PRELP PRELP PF4V1 PF4V1 ADAMTS15 ADAMTS15 CCL23 CCL23 THBS2 THBS2 CRISPLD2 CRISPLD2 ENSRROP00000029236 ENSRROP00000029236 PRG2 PRG2 NELL1 NELL1 CFH CFH COL23A1 COL23A1 LOC104680681 LOC104680681 LOC104682820 LOC104682820 LRRC3B LRRC3B F2 F2 LOC104670079 LOC104670079 PCOLCE PCOLCE POSTN POSTN FBN1 FBN1 LOC104655557 LOC104655557 PCSK6 PCSK6 IMPG1 IMPG1 CTSG CTSG SLIT2 SLIT2 SMOC2 SMOC2 NRP1 NRP1 CXCL1 CXCL1 SERPINC1 SERPINC1 NYX NYX FGFR1 FGFR1 EVA1C EVA1C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (830 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (345 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (370 aa)
ENSRROP00000024048Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (106 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
NAV2Neuron navigator 2. (2432 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (967 aa)
RSPO4R-spondin 4. (234 aa)
TENM1Tox-GHH domain-containing protein. (1364 aa)
COL5A1Collagen type V alpha 1 chain. (1841 aa)
RSPO3R-spondin 3. (293 aa)
CXCL6C-X-C motif chemokine. (123 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1311 aa)
LIPCLipase C, hepatic type. (499 aa)
FN1Fibronectin 1. (2479 aa)
RTN4RReticulon 4 receptor. (472 aa)
APOBApolipoprotein B. (4555 aa)
ENSRROP00000019340Uncharacterized protein. (68 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1172 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (459 aa)
LXNLatexin. (224 aa)
CCN3Cellular communication network factor 3. (357 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
CCL8C-C motif chemokine. (99 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
ENSRROP00000013321C-X-C motif chemokine. (102 aa)
LOC104655869Heparin binding growth factor. (154 aa)
CCN5Cellular communication network factor 5. (250 aa)
CCDC80Coiled-coil domain containing 80. (950 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
THBS3Thrombospondin 3. (956 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
LTFLactotransferrin; Belongs to the transferrin family. (732 aa)
FBLN7Fibulin 7. (441 aa)
PRSS57Serine protease 57; Belongs to the peptidase S1 family. (283 aa)
C6orf15Chromosome 6 open reading frame 15. (314 aa)
CCN1Cellular communication network factor 1. (381 aa)
ENSRROP00000008638Uncharacterized protein. (88 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
REG4Regenerating family member 4. (158 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
LRRC70Uncharacterized protein. (71 aa)
LOC104676447Uncharacterized protein. (109 aa)
ALKTyrosine-protein kinase receptor. (1011 aa)
SMOC1SPARC related modular calcium binding 1. (502 aa)
FGFRL1Fibroblast growth factor receptor like 1. (502 aa)
RSPO2R-spondin 2. (243 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RTN4RL1Reticulon 4 receptor like 1. (441 aa)
COL13A1Collagen type XIII alpha 1 chain. (717 aa)
PTNPleiotrophin. (167 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
FSTL1Follistatin like 1. (318 aa)
CXCL10C-X-C motif chemokine. (98 aa)
ENSRROP00000002567Uncharacterized protein. (129 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
MSTNMyostatin. (376 aa)
LRPAP1LDL receptor related protein associated protein 1. (358 aa)
MPOMyeloperoxidase. (745 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
PTCH1Patched 1. (1448 aa)
LRRC3Leucine rich repeat containing 3. (257 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGFR2Fibroblast growth factor receptor. (837 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1242 aa)
CDONCell adhesion associated, oncogene regulated. (1287 aa)
LIPGLipase G, endothelial type. (500 aa)
ENSRROP00000016893Fibronectin type-III domain-containing protein. (345 aa)
LOC104667644Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
SERPINA5Serpin family A member 5; Belongs to the serpin family. (406 aa)
ADAMTSL5ADAMTS like 5. (471 aa)
AAMPAngio associated migratory cell protein. (434 aa)
KNG1Kininogen 1. (644 aa)
LRRC3CUncharacterized protein. (275 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PF4C-X-C motif chemokine. (101 aa)
HRGHistidine rich glycoprotein. (526 aa)
ADA2Adenosine deaminase 2. (509 aa)
NDNFNeuron derived neurotrophic factor. (577 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
BSPH1Binder of sperm protein homolog 1. (116 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1865 aa)
LAMC2Laminin subunit gamma 2. (1224 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (687 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (930 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CCN2Cellular communication network factor 2. (387 aa)
LIPHLipase H. (455 aa)
THBS1Thrombospondin 1. (1170 aa)
SOSTSclerostin. (213 aa)
CCN4Cellular communication network factor 4. (367 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
CELCarboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. (709 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
AZU1Azurocidin 1. (250 aa)
SERPINA10Serpin family A member 10; Belongs to the serpin family. (477 aa)
RPL22Ribosomal protein L22. (128 aa)
TMEM184ATransmembrane protein 184A. (413 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
GPNMBGlycoprotein nmb. (561 aa)
SLIT1Slit guidance ligand 1. (1529 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (241 aa)
COL5A3Collagen type V alpha 3 chain. (1746 aa)
CXCL13C-X-C motif chemokine. (109 aa)
CLEC3BC-type lectin domain family 3 member B. (202 aa)
SELPSelectin P. (830 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
ENSRROP00000038268Uncharacterized protein. (58 aa)
LOC104667643Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
ELSPBP1Epididymal sperm binding protein 1. (223 aa)
AOC1Amine oxidase. (755 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (263 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
APLP1Amyloid beta precursor like protein 1. (680 aa)
ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif 8. (960 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
RSPO1R-spondin 1. (262 aa)
LOC104678227C-C motif chemokine. (109 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
LOC104675518Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (65 aa)
THBS4Thrombospondin 4. (961 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
CCN6Cellular communication network factor 6. (372 aa)
APOA5Apolipoprotein A5. (366 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (499 aa)
APLP2Amyloid beta precursor like protein 2. (757 aa)
ENSRROP00000034894Uncharacterized protein. (124 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
PCOLCE2Procollagen C-endopeptidase enhancer 2. (236 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (413 aa)
TNXBUncharacterized protein. (3671 aa)
APOHApolipoprotein H. (345 aa)
TMEM184BTransmembrane protein 184B. (414 aa)
ABI3BPFibronectin type-III domain-containing protein. (1341 aa)
PLA2G2DPhospholipase A(2). (145 aa)
APPAmyloid beta precursor protein. (770 aa)
COL25A1Collagen type XXV alpha 1 chain. (654 aa)
CXCL11C-X-C motif chemokine. (94 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1913 aa)
MDKUncharacterized protein. (143 aa)
ECM2Extracellular matrix protein 2. (695 aa)
PRELPProline and arginine rich end leucine rich repeat protein. (382 aa)
PF4V1C-X-C motif chemokine. (101 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (950 aa)
CCL23C-C motif chemokine. (120 aa)
THBS2Thrombospondin 2. (1172 aa)
CRISPLD2Cysteine rich secretory protein LCCL domain containing 2. (497 aa)
ENSRROP00000029236Uncharacterized protein. (61 aa)
PRG2C-type lectin domain-containing protein. (222 aa)
NELL1Neural EGFL like 1. (454 aa)
CFHUncharacterized protein. (1187 aa)
COL23A1Collagen type XXIII alpha 1 chain. (543 aa)
LOC104680681Uncharacterized protein. (525 aa)
LOC104682820Uncharacterized protein. (143 aa)
LRRC3BLeucine rich repeat containing 3B. (259 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
LOC104670079Uncharacterized protein. (128 aa)
PCOLCEProcollagen C-endopeptidase enhancer. (520 aa)
POSTNPeriostin. (847 aa)
FBN1Fibrillin 1. (2871 aa)
LOC104655557Uncharacterized protein. (128 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (932 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (796 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
SLIT2Slit guidance ligand 2. (1224 aa)
SMOC2SPARC related modular calcium binding 2. (457 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
CXCL1C-X-C motif chemokine. (107 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (464 aa)
NYXNyctalopin. (418 aa)
FGFR1Fibroblast growth factor receptor. (872 aa)
EVA1CEva-1 homolog C. (440 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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