STRINGSTRING
ACE ACE SRD5A2 SRD5A2 SF1 SF1 SPATA2 SPATA2 KIF18A KIF18A ADAM15 ADAM15 ARID4B ARID4B LOC104678360 LOC104678360 SMAD4 SMAD4 NR5A1 NR5A1 GATA4 GATA4 ERCC1 ERCC1 CRKL CRKL KDM5A KDM5A ENSRROP00000039864 ENSRROP00000039864 CSDE1 CSDE1 ASPM ASPM PDGFRB PDGFRB SFRP1 SFRP1 TMF1 TMF1 BCL2 BCL2 LHX9 LHX9 FSHR FSHR TFAP2C TFAP2C MAMLD1 MAMLD1 KIT KIT TFPT TFPT REC8 REC8 CSMD1 CSMD1 INHA INHA TGFB2 TGFB2 LOC104670092 LOC104670092 ARID5B ARID5B CITED2 CITED2 NUPR1 NUPR1 CSMD2 CSMD2 CBL CBL SOX8 SOX8 LOC104681170 LOC104681170 BIK BIK BCL2L11 BCL2L11 BCL2L1 BCL2L1 PATZ1 PATZ1 RAB13 RAB13 SOX9 SOX9 NUP210L NUP210L AR AR RXFP2 RXFP2 AKR1C3 AKR1C3 LHCGR LHCGR BOK BOK NR0B1 NR0B1 TGFBR1 TGFBR1 WNT4 WNT4 KITLG KITLG LRP2 LRP2 AGO4 AGO4 HOXA10 HOXA10 NKX3-1 NKX3-1 SOX15 SOX15 GATA3 GATA3 FNDC3A FNDC3A AMHR2 AMHR2 DMRT1 DMRT1 GATA1 GATA1 DHH DHH INHBA INHBA FGF9 FGF9 ARID4A ARID4A PLEKHA1 PLEKHA1 NCOA4 NCOA4 LOC104669796 LOC104669796 SDC1 SDC1 RHOBTB3 RHOBTB3 WNT2B WNT2B RARA RARA ATN1 ATN1 ING2 ING2 TCF21 TCF21 PDGFA PDGFA KLHL10 KLHL10 WNT5A WNT5A LOC104668178 LOC104668178 TESC TESC INHBB INHBB ENSRROP00000014443 ENSRROP00000014443 BRIP1 BRIP1 REN REN NTRK1 NTRK1 GFRA1 GFRA1 HOXA11 HOXA11 COL9A3 COL9A3 WDR48 WDR48 YBX3 YBX3 SGPL1 SGPL1 AMH AMH FANCA FANCA ENSRROP00000008738 ENSRROP00000008738 TNFSF10 TNFSF10 NHLH2 NHLH2 ATRX ATRX CYP1B1 CYP1B1 NUDT1 NUDT1 HSD17B4 HSD17B4 ADAM21 ADAM21 BAX BAX NASP NASP MAS1 MAS1 FER FER WT1 WT1 TBC1D20 TBC1D20 ACVR2A ACVR2A NKX2-1 NKX2-1 SIX4 SIX4 SFRP2 SFRP2 PRDX4 PRDX4 SAFB2 SAFB2 TLR3 TLR3 GATA6 GATA6 LRRC6 LRRC6 MSH2 MSH2 CTNNA1 CTNNA1 RNF38 RNF38
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACEAngiotensin-converting enzyme. (1307 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
SF1Splicing factor 1. (589 aa)
SPATA2Spermatogenesis associated 2. (520 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
ADAM15ADAM metallopeptidase domain 15. (864 aa)
ARID4BAT-rich interaction domain 4B. (1314 aa)
LOC104678360Nuclear receptor domain-containing protein. (231 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
GATA4GATA binding protein 4. (417 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (322 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
KDM5ALysine demethylase 5A. (1690 aa)
ENSRROP00000039864Homeobox domain-containing protein. (142 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ASPMAbnormal spindle microtubule assembly. (3478 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
TMF1TATA element modulatory factor 1. (1092 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
LHX9LIM homeobox 9. (397 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
TFAP2CTranscription factor AP-2 gamma. (450 aa)
MAMLD1Mastermind like domain containing 1. (956 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa)
TFPTTCF3 fusion partner. (263 aa)
REC8REC8 meiotic recombination protein. (522 aa)
CSMD1CUB and Sushi multiple domains 1. (3281 aa)
INHAInhibin subunit alpha. (413 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC104670092Uncharacterized protein. (69 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
CSMD2CUB and Sushi multiple domains 2. (3484 aa)
CBLCbl proto-oncogene. (906 aa)
SOX8SRY-box transcription factor 8. (425 aa)
LOC104681170Uncharacterized protein. (470 aa)
BIKBCL2 interacting killer. (157 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
BCL2L1BCL2 like 1. (233 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
RAB13Uncharacterized protein. (203 aa)
SOX9SRY-box transcription factor 9. (509 aa)
NUP210LNucleoporin 210 like. (1888 aa)
ARUncharacterized protein. (523 aa)
RXFP2Relaxin family peptide receptor 2. (748 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (323 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
LRP2LDL receptor related protein 2. (4655 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (828 aa)
HOXA10Homeobox A10. (410 aa)
NKX3-1NK3 homeobox 1. (232 aa)
SOX15SRY-box transcription factor 15. (233 aa)
GATA3GATA binding protein 3. (444 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (373 aa)
GATA1GATA binding protein 1. (413 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
INHBAInhibin subunit beta A. (492 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ARID4AAT-rich interaction domain 4A. (1258 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
NCOA4Nuclear receptor coactivator 4. (650 aa)
LOC104669796Uncharacterized protein. (316 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (325 aa)
RHOBTB3Rho related BTB domain containing 3. (611 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
RARARetinoic acid receptor alpha. (478 aa)
ATN1Atrophin 1. (1247 aa)
ING2Inhibitor of growth protein. (280 aa)
TCF21Transcription factor 21. (179 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (169 aa)
KLHL10Kelch like family member 10. (608 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LOC104668178Uncharacterized protein. (392 aa)
TESCTescalcin. (214 aa)
INHBBInhibin subunit beta B. (396 aa)
ENSRROP00000014443Uncharacterized protein. (608 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1249 aa)
RENRenin; Belongs to the peptidase A1 family. (406 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
GFRA1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (467 aa)
HOXA11Homeobox A11. (313 aa)
COL9A3Uncharacterized protein. (684 aa)
WDR48WD repeat domain 48. (700 aa)
YBX3Y-box binding protein 3. (371 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
AMHAnti-Mullerian hormone. (516 aa)
FANCAFA complementation group A. (1455 aa)
ENSRROP00000008738Peptidase M12B domain-containing protein. (170 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
ATRXUncharacterized protein. (164 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
NUDT1Nudix hydrolase 1; Belongs to the Nudix hydrolase family. (197 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (759 aa)
ADAM21ADAM metallopeptidase domain 21. (722 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
NASPNuclear autoantigenic sperm protein. (787 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
WT1WT1 transcription factor. (500 aa)
TBC1D20TBC1 domain family member 20. (403 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NKX2-1NK2 homeobox 1. (401 aa)
SIX4SIX homeobox 4. (780 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
PRDX4Peroxiredoxin 4. (271 aa)
SAFB2Scaffold attachment factor B2. (994 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
GATA6GATA binding protein 6. (548 aa)
LRRC6Leucine rich repeat containing 6. (466 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
CTNNA1Catenin alpha 1. (906 aa)
RNF38Ring finger protein 38. (517 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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