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POLD1 POLD1 SNCB SNCB BAG3 BAG3 PRNP PRNP ATXN3 ATXN3 STUB1 STUB1 NBN NBN LOC104663968 LOC104663968 HOXC9 HOXC9 PRKCQ PRKCQ STRADB STRADB GYS1 GYS1 ARIH1 ARIH1 SFMBT2 SFMBT2 DVL2 DVL2 SKOR2 SKOR2 SLF1 SLF1 CABIN1 CABIN1 ATXN1 ATXN1 TRIM66 TRIM66 PSMC6 PSMC6 FBXO7 FBXO7 NUP98 NUP98 GPX1 GPX1 NEFM NEFM CARD14 CARD14 MT3 MT3 KLF8 KLF8 ATF4 ATF4 DNAJB2 DNAJB2 ZBTB14 ZBTB14 HSPB7 HSPB7 PRKN PRKN WDFY3 WDFY3 NUP153 NUP153 ENSRROP00000000720 ENSRROP00000000720 HAP1 HAP1 TDP2 TDP2 UBD UBD TPR TPR PRDM16 PRDM16 PSEN1 PSEN1 KLHL14 KLHL14 RANGAP1 RANGAP1 BCL2L2-PABPN1 BCL2L2-PABPN1 HOXD3 HOXD3 EDEM1 EDEM1 XRN2 XRN2 RAD18 RAD18 HDAC6 HDAC6 PSMC5 PSMC5 LOC104654801 LOC104654801 ENSRROP00000040307 ENSRROP00000040307 TRIM37 TRIM37 PICALM PICALM BAG5 BAG5 LRRK2 LRRK2 EPS15 EPS15 KEAP1 KEAP1 NEFH NEFH IAPP IAPP CLU CLU AGL AGL ENSRROP00000033668 ENSRROP00000033668 FGR FGR ZDHHC17 ZDHHC17 URB2 URB2 HTT HTT PINK1 PINK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLD1DNA polymerase. (1143 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (134 aa)
BAG3BCL2 associated athanogene 3. (524 aa)
PRNPMajor prion protein; Belongs to the prion family. (230 aa)
ATXN3Ataxin 3. (365 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (753 aa)
LOC104663968RRM domain-containing protein. (287 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
STRADBSTE20 related adaptor beta. (418 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
ARIH1RBR-type E3 ubiquitin transferase. (510 aa)
SFMBT2Scm like with four mbt domains 2. (876 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
SKOR2c-SKI_SMAD_bind domain-containing protein. (295 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1058 aa)
CABIN1Calcineurin binding protein 1. (2040 aa)
ATXN1Ataxin 1. (799 aa)
TRIM66Uncharacterized protein. (618 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
FBXO7F-box protein 7. (522 aa)
NUP98Nucleoporin 98. (1799 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (200 aa)
NEFMNeurofilament medium; Belongs to the intermediate filament family. (905 aa)
CARD14Caspase recruitment domain family member 14. (1001 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
KLF8Kruppel like factor 8. (359 aa)
ATF4Activating transcription factor 4. (351 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
ZBTB14Zinc finger and BTB domain containing 14. (449 aa)
HSPB7Heat shock protein family B (small) member 7; Belongs to the small heat shock protein (HSP20) family. (253 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
WDFY3WD repeat and FYVE domain containing 3. (3526 aa)
NUP153Nucleoporin 153. (1468 aa)
ENSRROP00000000720Uncharacterized protein. (325 aa)
HAP1Huntingtin associated protein 1. (644 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (388 aa)
UBDUbiquitin D. (165 aa)
TPRTranslocated promoter region, nuclear basket protein. (2438 aa)
PRDM16PR/SET domain 16. (1263 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
KLHL14Kelch like family member 14. (629 aa)
RANGAP1Ran GTPase activating protein 1. (621 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (323 aa)
HOXD3Homeobox D3. (430 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (657 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1063 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (496 aa)
HDAC6Histone deacetylase 6. (1258 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (444 aa)
LOC104654801Glutathione peroxidase; Belongs to the glutathione peroxidase family. (188 aa)
ENSRROP00000040307Josephin domain-containing protein. (101 aa)
TRIM37Tripartite motif containing 37. (963 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (674 aa)
BAG5BCL2 associated athanogene 5. (488 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (899 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
NEFHNeurofilament heavy; Belongs to the intermediate filament family. (997 aa)
IAPPIslet amyloid polypeptide. (86 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1532 aa)
ENSRROP00000033668RRM domain-containing protein. (297 aa)
FGRTyrosine-protein kinase. (529 aa)
ZDHHC17Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (632 aa)
URB2URB2 ribosome biogenesis homolog. (1524 aa)
HTTHuntingtin. (3100 aa)
PINK1PTEN induced kinase 1. (581 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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