(9 nodes) Growth hormone secretion network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSRROP00000028830	Uncharacterized protein. (136 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	ENSRROP00000015361	Uncharacterized protein. (190 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (136 aa)
	LOC104675287	Uncharacterized protein. (213 aa)
	CDK16	Cyclin dependent kinase 16. (570 aa)
	GHRH	Growth hormone releasing hormone. (107 aa)
	RAB1A	Uncharacterized protein. (188 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GHRH	GHRHR	ENSRROP00000037531	ENSRROP00000013305	Growth hormone releasing hormone.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.998
GHRH	GHRL	ENSRROP00000037531	ENSRROP00000002678	Growth hormone releasing hormone.	Ghrelin and obestatin prepropeptide.	0.716
GHRH	GHSR	ENSRROP00000037531	ENSRROP00000023050	Growth hormone releasing hormone.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.668
GHRHR	GHRH	ENSRROP00000013305	ENSRROP00000037531	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	Growth hormone releasing hormone.	0.998
GHRHR	GHRL	ENSRROP00000013305	ENSRROP00000002678	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	Ghrelin and obestatin prepropeptide.	0.493
GHRHR	GHSR	ENSRROP00000013305	ENSRROP00000023050	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.573
GHRL	GHRH	ENSRROP00000002678	ENSRROP00000037531	Ghrelin and obestatin prepropeptide.	Growth hormone releasing hormone.	0.716
GHRL	GHRHR	ENSRROP00000002678	ENSRROP00000013305	Ghrelin and obestatin prepropeptide.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.493
GHRL	GHSR	ENSRROP00000002678	ENSRROP00000023050	Ghrelin and obestatin prepropeptide.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.998
GHSR	GHRH	ENSRROP00000023050	ENSRROP00000037531	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Growth hormone releasing hormone.	0.668
GHSR	GHRHR	ENSRROP00000023050	ENSRROP00000013305	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.573
GHSR	GHRL	ENSRROP00000023050	ENSRROP00000002678	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Ghrelin and obestatin prepropeptide.	0.998