STRINGSTRING
SEMA3A SEMA3A DAB2 DAB2 HYAL2 HYAL2 SEMA4F SEMA4F IFRD1 IFRD1 RERG RERG ENSRROP00000038862 ENSRROP00000038862 FSTL4 FSTL4 SFRP1 SFRP1 BST2 BST2 RBBP7 RBBP7 BCL2 BCL2 ULK1 ULK1 SERPINE2 SERPINE2 MSX1 MSX1 TGFB2 TGFB2 GNG4 GNG4 BMP10 BMP10 LOC104675163 LOC104675163 IFRD2 IFRD2 RACK1 RACK1 PPP2R1A PPP2R1A DIP2B DIP2B ENSRROP00000030520 ENSRROP00000030520 ENSRROP00000030174 ENSRROP00000030174 PHB PHB LOC104668767 LOC104668767 DRAXIN DRAXIN ENSRROP00000029809 ENSRROP00000029809 FBP1 FBP1 WNT3 WNT3 SPP1 SPP1 SEMA3B SEMA3B ZC3H12D ZC3H12D SEMA4D SEMA4D TP53TG5 TP53TG5 SPAG9 SPAG9 FHL1 FHL1 SEMA3E SEMA3E PPP2CA PPP2CA SEMA5A SEMA5A CDKL3 CDKL3 PSRC1 PSRC1 NRP1 NRP1 SLIT2 SLIT2 BCL11A BCL11A ST7L ST7L DDX3Y DDX3Y PPT1 PPT1 SMARCA2 SMARCA2 ULK2 ULK2 WT1 WT1 CYP27B1 CYP27B1 MYL10 MYL10 STK11 STK11 ENSRROP00000005643 ENSRROP00000005643 ENSRROP00000005692 ENSRROP00000005692 BCL6 BCL6 TSPYL2 TSPYL2 SMAD3 SMAD3 SERTAD1 SERTAD1 MT3 MT3 RTN4 RTN4 SERTAD2 SERTAD2 ENSRROP00000007319 ENSRROP00000007319 DCC DCC MUL1 MUL1 CGRRF1 CGRRF1 DNAJB2 DNAJB2 OSTN OSTN SEMA4G SEMA4G PPARD PPARD NME6 NME6 OSGIN2 OSGIN2 DCUN1D3 DCUN1D3 CDKN2AIP CDKN2AIP CDA CDA SEMA3G SEMA3G BMPR2 BMPR2 LOC104680554 LOC104680554 JADE1 JADE1 WNT3A WNT3A SLIT3 SLIT3 EI24 EI24 LOC104657019 LOC104657019 EAF2 EAF2 GSK3A GSK3A CAV3 CAV3 PML PML GDF2 GDF2 AGTR2 AGTR2 DCBLD2 DCBLD2 SIPA1 SIPA1 ENSRROP00000003223 ENSRROP00000003223 SERTAD3 SERTAD3 SFRP2 SFRP2 CCDC85B CCDC85B TOMM70 TOMM70 SPART SPART SEMA4C SEMA4C RGS2 RGS2 SLIT1 SLIT1 SCGB3A1 SCGB3A1 PPP1R9B PPP1R9B SEMA4A SEMA4A SEMA7A SEMA7A TGFB1 TGFB1 NDUFA13 NDUFA13 ST20 ST20 DDX3X DDX3X HNF4A HNF4A PTPRJ PTPRJ SEMA3D SEMA3D CDKN2C CDKN2C KIAA0319 KIAA0319 ENSRROP00000013117 ENSRROP00000013117 SEMA5B SEMA5B WNT11 WNT11 IP6K2 IP6K2 ENSRROP00000014051 ENSRROP00000014051 HYAL1 HYAL1 NDUFS3 NDUFS3 SH3BP4 SH3BP4 DCSTAMP DCSTAMP CCN3 CCN3 CRLF3 CRLF3 SOX17 SOX17 EPHA7 EPHA7 PPARA PPARA MINAR1 MINAR1 WNT5A WNT5A C10orf90 C10orf90 MYL2 MYL2 NPPB NPPB MAP2 MAP2 ACVRL1 ACVRL1 VGLL4 VGLL4 PI16 PI16 CAPRIN2 CAPRIN2 HRG HRG G6PD G6PD CDHR2 CDHR2 NPR1 NPR1 DACT3 DACT3 SEMA6C SEMA6C SEMA4B SEMA4B PRDM11 PRDM11 SMAD4 SMAD4 FOXP1 FOXP1 PLXNA3 PLXNA3 ENSRROP00000044217 ENSRROP00000044217 SEMA6A SEMA6A ADAM15 ADAM15 WFDC1 WFDC1 SESN2 SESN2 FRZB FRZB ARHGAP4 ARHGAP4 SMARCA4 SMARCA4 PTPRS PTPRS OSGIN1 OSGIN1 CDKN1B CDKN1B ENSRROP00000026787 ENSRROP00000026787 TP53 TP53 TRIM46 TRIM46 TCHP TCHP CDKN1A CDKN1A RYK RYK NTN1 NTN1 FLCN FLCN SEMA6B SEMA6B ENSRROP00000019455 ENSRROP00000019455 CDK5 CDK5 SEMA3F SEMA3F ACVR1B ACVR1B TNR TNR CDKN2D CDKN2D MAG MAG CCAR2 CCAR2 SIRT1 SIRT1 RNF6 RNF6 GDF9 GDF9 ENPP1 ENPP1 INHBA INHBA RTN4R RTN4R CTDP1 CTDP1 GAS2L1 GAS2L1 BTG1 BTG1 ING1 ING1 RB1 RB1 SPHK2 SPHK2 FGF13 FGF13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
DAB2DAB adaptor protein 2. (749 aa)
HYAL2Hyaluronidase. (473 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
IFRD1Interferon related developmental regulator 1. (451 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
ENSRROP00000038862Protein kinase domain-containing protein. (265 aa)
FSTL4Follistatin like 4. (842 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
BST2Bone marrow stromal cell antigen 2. (182 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1013 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (413 aa)
MSX1Msh homeobox 1. (261 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
LOC104675163RING-type domain-containing protein. (319 aa)
IFRD2Uncharacterized protein. (510 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
DIP2BDisco interacting protein 2 homolog B. (1576 aa)
ENSRROP00000030520Uncharacterized protein. (265 aa)
ENSRROP00000030174annotation not available (136 aa)
PHBProhibitin. (272 aa)
LOC104668767Uncharacterized protein. (327 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (348 aa)
ENSRROP00000029809Prohibitin. (264 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (409 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
SPP1Secreted phosphoprotein 1. (324 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (748 aa)
ZC3H12DZinc finger CCCH-type containing 12D. (526 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
TP53TG5TP53 target 5. (290 aa)
SPAG9Sperm associated antigen 9. (1339 aa)
FHL1Four and a half LIM domains 1. (339 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
SEMA5ASemaphorin 5A. (1056 aa)
CDKL3Cyclin dependent kinase like 3. (591 aa)
PSRC1Proline and serine rich coiled-coil 1. (333 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
SLIT2Slit guidance ligand 2. (1224 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
ST7LSuppression of tumorigenicity 7 like. (575 aa)
DDX3YDEAD-box helicase 3 Y-linked; Belongs to the DEAD box helicase family. (661 aa)
PPT1Palmitoyl-protein thioesterase 1. (335 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1570 aa)
ULK2DUF3543 domain-containing protein. (527 aa)
WT1WT1 transcription factor. (500 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
MYL10Myosin light chain 10. (208 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
ENSRROP00000005643Uncharacterized protein. (495 aa)
ENSRROP00000005692DCN1-like protein. (304 aa)
BCL6BCL6 transcription repressor. (706 aa)
TSPYL2TSPY like 2; Belongs to the nucleosome assembly protein (NAP) family. (495 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
SERTAD1SERTA domain containing 1. (236 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
RTN4Reticulon. (1138 aa)
SERTAD2SERTA domain containing 2. (314 aa)
ENSRROP00000007319Uncharacterized protein. (89 aa)
DCCDCC netrin 1 receptor. (1065 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
CGRRF1RING-type domain-containing protein. (332 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
OSTNOsteocrin. (133 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
OSGIN2Oxidative stress induced growth inhibitor family member 2. (547 aa)
DCUN1D3DCN1-like protein. (304 aa)
CDKN2AIPCDKN2A interacting protein. (579 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (783 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1002 aa)
LOC104680554Uncharacterized protein. (89 aa)
JADE1Jade family PHD finger 1. (870 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
EI24Uncharacterized protein. (349 aa)
LOC104657019Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
EAF2ELL associated factor 2. (263 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (428 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PMLPromyelocytic leukemia. (882 aa)
GDF2Growth differentiation factor 2. (429 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
DCBLD2Discoidin, CUB and LCCL domain containing 2. (775 aa)
SIPA1Signal-induced proliferation-associated 1. (1042 aa)
ENSRROP00000003223Uncharacterized protein. (285 aa)
SERTAD3SERTA domain containing 3. (196 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
CCDC85BCoiled-coil domain containing 85B. (202 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
SPARTSpartin. (666 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
SLIT1Slit guidance ligand 1. (1529 aa)
SCGB3A1Secretoglobin family 3A member 1. (102 aa)
PPP1R9BUncharacterized protein. (98 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (778 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (151 aa)
ST20Uncharacterized protein. (78 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (723 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1337 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (778 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
KIAA0319KIAA0319. (1028 aa)
ENSRROP00000013117Prohibitin. (179 aa)
SEMA5BSemaphorin 5B. (1195 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (465 aa)
ENSRROP00000014051IFRD_C domain-containing protein. (136 aa)
HYAL1Hyaluronidase. (435 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
CCN3Cellular communication network factor 3. (357 aa)
CRLF3Cytokine receptor like factor 3. (361 aa)
SOX17SRY-box transcription factor 17. (412 aa)
EPHA7EPH receptor A7. (998 aa)
PPARAPeroxisome proliferator activated receptor alpha. (398 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (916 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
C10orf90Chromosome 10 open reading frame 90. (695 aa)
MYL2Myosin light chain 2. (166 aa)
NPPBNatriuretic peptide B. (134 aa)
MAP2Microtubule-associated protein. (1827 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
VGLL4Vestigial like family member 4. (296 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (466 aa)
CAPRIN2Caprin family member 2. (923 aa)
HRGHistidine rich glycoprotein. (526 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (545 aa)
CDHR2Cadherin related family member 2. (1310 aa)
NPR1Guanylate cyclase. (1284 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (571 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (961 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (956 aa)
PRDM11PR/SET domain 11. (1177 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FOXP1Forkhead box P1. (694 aa)
PLXNA3Plexin A3. (1876 aa)
ENSRROP00000044217DCN1-like protein. (295 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
ADAM15ADAM metallopeptidase domain 15. (864 aa)
WFDC1WAP four-disulfide core domain 1. (220 aa)
SESN2Sestrin 2. (518 aa)
FRZBFrizzled related protein. (325 aa)
ARHGAP4Rho GTPase activating protein 4. (781 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1865 aa)
OSGIN1Oxidative stress induced growth inhibitor 1. (556 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ENSRROP00000026787Prohibitin. (190 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
TRIM46Tripartite motif containing 46. (559 aa)
TCHPTrichoplein keratin filament binding. (498 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
RYKReceptor like tyrosine kinase. (623 aa)
NTN1Netrin 1. (604 aa)
FLCNFolliculin. (579 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (652 aa)
ENSRROP00000019455LIM zinc-binding domain-containing protein. (185 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
TNRTenascin R. (1358 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
MAGMyelin associated glycoprotein. (626 aa)
CCAR2Cell cycle and apoptosis regulator 2. (923 aa)
SIRT1Sirtuin 1. (746 aa)
RNF6Ring finger protein 6. (701 aa)
GDF9Growth differentiation factor 9. (455 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (917 aa)
INHBAInhibin subunit beta A. (492 aa)
RTN4RReticulon 4 receptor. (472 aa)
CTDP1CTD phosphatase subunit 1. (947 aa)
GAS2L1Growth arrest specific 2 like 1. (681 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
ING1Inhibitor of growth protein. (406 aa)
RB1RB transcriptional corepressor 1. (929 aa)
SPHK2Sphingosine kinase 2. (665 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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