STRINGSTRING
ENSRROP00000036642 ENSRROP00000036642 TRERF1 TRERF1 TADA3 TADA3 ACTN4 ACTN4 ENSRROP00000043547 ENSRROP00000043547 PPRC1 PPRC1 ENY2-2 ENY2-2 NCOA3 NCOA3 CNOT9 CNOT9 RBM14 RBM14 CCDC62 CCDC62 SS18 SS18 ENSRROP00000038177 ENSRROP00000038177 TMF1 TMF1 NCOA1 NCOA1 DCAF6 DCAF6 ELK1 ELK1 KDM1A KDM1A ATXN7L3 ATXN7L3 NCOA2 NCOA2 ENSRROP00000032053 ENSRROP00000032053 CCAR1 CCAR1 MED14 MED14 SMARCD3 SMARCD3 RNF4 RNF4 MED1 MED1 MED24 MED24 BRD8 BRD8 TACC1 TACC1 LOC104667986 LOC104667986 ACTN1 ACTN1 BUD31 BUD31 CNOT6 CNOT6 CALCOCO1 CALCOCO1 ENY2 ENY2 ENSRROP00000021314 ENSRROP00000021314 PRKCB PRKCB CARM1 CARM1 PSMC3IP PSMC3IP ZMIZ1 ZMIZ1 ZMIZ2 ZMIZ2 NCOA7 NCOA7 MED13 MED13 NCOA6 NCOA6 PPARGC1B PPARGC1B MED30 MED30 THRAP3 THRAP3 ACTN2 ACTN2 SFR1 SFR1 MED4 MED4 HMGA1 HMGA1 ENSRROP00000004544 ENSRROP00000004544 ETS1 ETS1 PKN1 PKN1 SRA1 SRA1 PPARGC1A PPARGC1A HELZ2 HELZ2 TSG101 TSG101
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRROP00000036642Phorbol-ester/DAG-type domain-containing protein. (57 aa)
TRERF1Transcriptional regulating factor 1. (1219 aa)
TADA3Transcriptional adaptor 3. (432 aa)
ACTN4Actinin alpha 4. (931 aa)
ENSRROP00000043547Uncharacterized protein. (106 aa)
PPRC1PPARG related coactivator 1. (1663 aa)
ENY2-2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (92 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
CNOT9Uncharacterized protein. (331 aa)
RBM14RNA binding motif protein 14. (669 aa)
CCDC62Coiled-coil domain containing 62. (683 aa)
SS18SS18 subunit of BAF chromatin remodeling complex. (418 aa)
ENSRROP00000038177Uncharacterized protein. (277 aa)
TMF1TATA element modulatory factor 1. (1092 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
DCAF6DDB1 and CUL4 associated factor 6. (951 aa)
ELK1Uncharacterized protein. (428 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (400 aa)
NCOA2Nuclear receptor coactivator. (1475 aa)
ENSRROP00000032053SCA7 domain-containing protein. (289 aa)
CCAR1Cell division cycle and apoptosis regulator 1. (1150 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (386 aa)
RNF4Ring finger protein 4. (190 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
MED24Mediator complex subunit 24. (1008 aa)
BRD8Bromodomain containing 8. (1235 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (806 aa)
LOC104667986Uncharacterized protein. (96 aa)
ACTN1Actinin alpha 1. (930 aa)
BUD31BUD31 homolog. (144 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (584 aa)
CALCOCO1Calcium binding and coiled-coil domain 1. (691 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
ENSRROP00000021314ETS domain-containing protein. (421 aa)
PRKCBNon-specific serine/threonine protein kinase. (590 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (564 aa)
PSMC3IPPSMC3 interacting protein. (217 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1067 aa)
ZMIZ2Zinc finger MIZ-type containing 2. (886 aa)
NCOA7Nuclear receptor coactivator 7. (942 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2087 aa)
NCOA6Nuclear receptor coactivator 6. (2069 aa)
PPARGC1BPPARG coactivator 1 beta. (1024 aa)
MED30Mediator complex subunit 30. (178 aa)
THRAP3Thyroid hormone receptor associated protein 3. (955 aa)
ACTN2Actinin alpha 2. (894 aa)
SFR1SWI5 dependent homologous recombination repair protein 1. (245 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
HMGA1Uncharacterized protein. (105 aa)
ENSRROP00000004544Uncharacterized protein. (402 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
PKN1Protein kinase N1. (965 aa)
SRA1Steroid receptor RNA activator 1. (235 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
HELZ2Helicase with zinc finger 2. (2822 aa)
TSG101Tumor susceptibility 101. (390 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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