83 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (875 aa)
	ENSRROP00000036403	PPM-type phosphatase domain-containing protein. (342 aa)
	LDLRAD4	Low density lipoprotein receptor class A domain containing 4. (306 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	SMAD6	MH2 domain-containing protein. (226 aa)
	SMAD7	MH2 domain-containing protein. (211 aa)
	HTRA3	HtrA serine peptidase 3. (453 aa)
	ENSRROP00000041143	Uncharacterized protein; Belongs to the heat shock protein 70 family. (573 aa)
	SPRED3	Sprouty related EVH1 domain containing 3. (442 aa)
	CD109	CD109 molecule. (1449 aa)
	SKIL	SKI like proto-oncogene. (684 aa)
	SIN3A	SIN3 transcription regulator family member A. (1273 aa)
	LEMD3	LEM domain containing 3. (911 aa)
	FBN2	Fibrillin 2. (2912 aa)
	WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
	ARID4B	AT-rich interaction domain 4B. (1314 aa)
	SPINT3	Serine peptidase inhibitor, Kunitz type 3. (89 aa)
	BAMBI	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
	ING2	Inhibitor of growth protein. (280 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (338 aa)
	STRAP	Serine/threonine kinase receptor associated protein. (363 aa)
	DAND5	DAN domain BMP antagonist family member 5. (189 aa)
	SLC2A10	Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	PMEPA1	Prostate transmembrane protein, androgen induced 1. (257 aa)
	FAM89B	Family with sequence similarity 89 member B. (189 aa)
	SMURF1	E3 ubiquitin-protein ligase. (764 aa)
	SNX25	Sorting nexin 25. (859 aa)
	SIRT1	Sirtuin 1. (746 aa)
	GLG1	Golgi glycoprotein 1. (1193 aa)
	ENSRROP00000024190	Protein kinase domain-containing protein. (137 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	ONECUT2	One cut domain family member. (455 aa)
	ADAMTSL2	ADAMTS like 2. (1053 aa)
	ZNF451	Zinc finger protein 451. (1061 aa)
	XBP1	BZIP domain-containing protein. (380 aa)
	ING1	Inhibitor of growth protein. (406 aa)
	BRMS1	BRMS1 transcriptional repressor and anoikis regulator. (246 aa)
	TGFBR3	Transforming growth factor beta receptor 3. (860 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (398 aa)
	SPRED2	Sprouty related EVH1 domain containing 2. (432 aa)
	SKI	SKI proto-oncogene. (770 aa)
	ENSRROP00000011768	Peptidyl-prolyl cis-trans isomerase. (154 aa)
	BMP2	Bone morphogenetic protein 2. (470 aa)
	RASL11B	RAS like family 11 member B. (248 aa)
	ENG	Endoglin. (658 aa)
	EMILIN1	Elastin microfibril interfacer 1. (1016 aa)
	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	PBLD	Phenazine biosynthesis like protein domain containing. (288 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (584 aa)
	LINGO3	Leucine rich repeat and Ig domain containing 3. (592 aa)
	SAP30L	SAP30 like. (188 aa)
	IL17RD	Interleukin 17 receptor D. (738 aa)
	ASPN	Asporin. (374 aa)
	MTMR4	Myotubularin related protein 4. (1195 aa)
	PRDM16	PR/SET domain 16. (1263 aa)
	NKX2-1	NK2 homeobox 1. (401 aa)
	SMURF2	E3 ubiquitin-protein ligase. (741 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (356 aa)
	EID2	EP300 interacting inhibitor of differentiation 2. (236 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	SAP30	Sin3A associated protein 30. (124 aa)
	NRROS	Negative regulator of reactive oxygen species. (692 aa)
	VASN	Vasorin. (673 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
	SPRED1	Sprouty related EVH1 domain containing 1. (444 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (456 aa)
	CIDEA	Cell death inducing DFFA like effector a. (219 aa)
	FBN1	Fibrillin 1. (2871 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (303 aa)
	ADAM17	ADAM metallopeptidase domain 17. (824 aa)
	HTRA4	HtrA serine peptidase 4. (476 aa)
	BRMS1L	BRMS1 like transcriptional repressor. (323 aa)
	WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
	SAP130	Sin3A associated protein 130. (1083 aa)
	HTRA1	HtrA serine peptidase 1. (477 aa)
	VEPH1	Ventricular zone expressed PH domain containing 1. (822 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (167 aa)
	BCL9L	BCL9 like. (1500 aa)
	TET1	Tet methylcytosine dioxygenase 1. (2132 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTSL2	FBN1	ENSRROP00000026723	ENSRROP00000027582	ADAMTS like 2.	Fibrillin 1.	0.501
ARID4B	BRMS1	ENSRROP00000044493	ENSRROP00000026204	AT-rich interaction domain 4B.	BRMS1 transcriptional repressor and anoikis regulator.	0.982
ARID4B	BRMS1L	ENSRROP00000044493	ENSRROP00000030186	AT-rich interaction domain 4B.	BRMS1 like transcriptional repressor.	0.984
ARID4B	HDAC2	ENSRROP00000044493	ENSRROP00000017767	AT-rich interaction domain 4B.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.920
ARID4B	ING1	ENSRROP00000044493	ENSRROP00000023176	AT-rich interaction domain 4B.	Inhibitor of growth protein.	0.789
ARID4B	ING2	ENSRROP00000044493	ENSRROP00000016318	AT-rich interaction domain 4B.	Inhibitor of growth protein.	0.686
ARID4B	SAP130	ENSRROP00000044493	ENSRROP00000030369	AT-rich interaction domain 4B.	Sin3A associated protein 130.	0.801
ARID4B	SAP30	ENSRROP00000044493	ENSRROP00000000630	AT-rich interaction domain 4B.	Sin3A associated protein 30.	0.986
ARID4B	SAP30L	ENSRROP00000044493	ENSRROP00000006579	AT-rich interaction domain 4B.	SAP30 like.	0.976
ARID4B	SIN3A	ENSRROP00000044493	ENSRROP00000043335	AT-rich interaction domain 4B.	SIN3 transcription regulator family member A.	0.937
ARID4B	TET1	ENSRROP00000044493	ENSRROP00000035029	AT-rich interaction domain 4B.	Tet methylcytosine dioxygenase 1.	0.586
BAMBI	SMAD6	ENSRROP00000045214	ENSRROP00000039911	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	MH2 domain-containing protein.	0.749
BAMBI	SMAD7	ENSRROP00000045214	ENSRROP00000040471	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	MH2 domain-containing protein.	0.854
BMP2	EMILIN1	ENSRROP00000011353	ENSRROP00000010206	Bone morphogenetic protein 2.	Elastin microfibril interfacer 1.	0.416
BMP2	ENG	ENSRROP00000011353	ENSRROP00000010798	Bone morphogenetic protein 2.	Endoglin.	0.468
BMP2	SMAD6	ENSRROP00000011353	ENSRROP00000039911	Bone morphogenetic protein 2.	MH2 domain-containing protein.	0.897
BMP2	SMAD7	ENSRROP00000011353	ENSRROP00000040471	Bone morphogenetic protein 2.	MH2 domain-containing protein.	0.589
BMP2	SMURF1	ENSRROP00000011353	ENSRROP00000019217	Bone morphogenetic protein 2.	E3 ubiquitin-protein ligase.	0.520
BMP2	SMURF2	ENSRROP00000011353	ENSRROP00000003728	Bone morphogenetic protein 2.	E3 ubiquitin-protein ligase.	0.520
BMP2	TGFBR3	ENSRROP00000011353	ENSRROP00000015337	Bone morphogenetic protein 2.	Transforming growth factor beta receptor 3.	0.492