STRINGSTRING
PKP1 PKP1 ALDH3B2 ALDH3B2 PTPRJ PTPRJ DYNC1LI1 DYNC1LI1 CADPS CADPS CKAP4 CKAP4 SPAM1 SPAM1 BRI3 BRI3 RAP2C RAP2C NBEAL2 NBEAL2 SYT1 SYT1 SPACA6 SPACA6 SYT4 SYT4 ITGAX ITGAX SYNGR1 SYNGR1 RAB27A RAB27A SNAP23 SNAP23 CD55 CD55 OLR1 OLR1 ENSRROP00000008301 ENSRROP00000008301 SIGLEC14-2 SIGLEC14-2 ITGAM ITGAM RAB31 RAB31 SYT9 SYT9 MCEMP1 MCEMP1 TRIP11 TRIP11 MLEC MLEC GPR84 GPR84 NCKAP1L NCKAP1L RHOF RHOF CD36 CD36 PECAM1 PECAM1 STXBP5 STXBP5 TBC1D10C TBC1D10C PLD1 PLD1 LOC104666756 LOC104666756 CD9 CD9 RHOG RHOG DSC1 DSC1 CD93 CD93 TEKT3 TEKT3 DGAT1 DGAT1 PTPRB PTPRB IZUMO1 IZUMO1 BST1 BST1 PLD1-2 PLD1-2 ANO6 ANO6 TMBIM1 TMBIM1 ITGAV ITGAV LOC104671192 LOC104671192 TMEM179B TMEM179B CD58 CD58 FAM170B FAM170B DSG1 DSG1 NFAM1 NFAM1 B4GALT1 B4GALT1 LOC104675305 LOC104675305 TARM1 TARM1 STING1 STING1 LAMTOR2 LAMTOR2 SYTL4 SYTL4 EQTN EQTN ENSRROP00000044300 ENSRROP00000044300 ABCA12 ABCA12 CD63 CD63 ITPR1 ITPR1 DBH DBH DNAJC5 DNAJC5 KCNAB2 KCNAB2 ABCC4 ABCC4 TMEM95 TMEM95 ITGB2 ITGB2 ENSRROP00000041470 ENSRROP00000041470 CD109 CD109 CD46 CD46 STK10 STK10 SLC15A4 SLC15A4 ZG16 ZG16 MOXD1 MOXD1 ACPP ACPP ATP11B ATP11B CLEC4D CLEC4D AZU1 AZU1 AP2A2 AP2A2 GLIPR1 GLIPR1 RAB4B RAB4B TMEM184A TMEM184A SLC27A2 SLC27A2 VNN1 VNN1 RAP1A RAP1A SELP SELP TEX101 TEX101 ICA1 ICA1 ADGRG3 ADGRG3 CA4 CA4 GP2 GP2 ABCA13 ABCA13 SLC30A8 SLC30A8 STX3 STX3 RND2 RND2 TMED2 TMED2 BST2 BST2 ITGA2B ITGA2B CEACAM6 CEACAM6 TSPAN14 TSPAN14 SLC17A9 SLC17A9 LGALS3 LGALS3 CYBA CYBA ENSRROP00000035964 ENSRROP00000035964 ATP8B4 ATP8B4 ITPR3 ITPR3 SLC30A5 SLC30A5 SPACA1 SPACA1 APLP2 APLP2 CD44 CD44 ENSRROP00000034704 ENSRROP00000034704 CHRNB4 CHRNB4 SLC11A1 SLC11A1 TMEM190 TMEM190 TOM1 TOM1 LAMP1 LAMP1 ADAM10 ADAM10 ABCA3 ABCA3 CCDC136 CCDC136 KIF1A KIF1A CLEC5A CLEC5A CLEC4C CLEC4C P2RX1 P2RX1 SYT2 SYT2 ENSRROP00000030240 ENSRROP00000030240 RAB24 RAB24 VAMP8 VAMP8 ATP6V0C ATP6V0C VNN3 VNN3 SYCN SYCN TNFRSF1B TNFRSF1B ITGAL ITGAL PAM PAM ADAM8 ADAM8 MGAM MGAM CD14 CD14 SYT5 SYT5 SCG3 SCG3 SIRPA SIRPA DSP DSP DMBT1 DMBT1 ANXA7 ANXA7 MGST1 MGST1 ZPBP ZPBP VPS13B VPS13B RAP2B RAP2B PCDH7 PCDH7 AGPAT2 AGPAT2 RAB44 RAB44 FCAR FCAR PIGR PIGR STOM STOM DNAJC13 DNAJC13 RAB27B RAB27B SIGLEC9 SIGLEC9 CYB561 CYB561 HVCN1 HVCN1 CD177 CD177 SCAMP1 SCAMP1 LOC104668202 LOC104668202 CYSTM1 CYSTM1 IGF2R IGF2R DIAPH1 DIAPH1 SPACA3 SPACA3 ACRBP ACRBP MS4A3 MS4A3 RAB26 RAB26 IQGAP1 IQGAP1 CD68 CD68 ADGRE5 ADGRE5 CLEC12A CLEC12A ENSRROP00000024302 ENSRROP00000024302 ENSRROP00000024205 ENSRROP00000024205 CAV1 CAV1 VAMP1 VAMP1 PLA1A PLA1A CYB5R1 CYB5R1 ATP11A ATP11A ALDH3B1 ALDH3B1 ITPR2 ITPR2 FABP5 FABP5 ITGB3 ITGB3 PCSK4 PCSK4 ENSRROP00000022810 ENSRROP00000022810 TCIRG1 TCIRG1 TMEM225 TMEM225 ENSRROP00000022469 ENSRROP00000022469 SERPINB12 SERPINB12 PTPRC PTPRC CD33 CD33 EXOC3 EXOC3 PHACTR2 PHACTR2 IQGAP2 IQGAP2 SIRPB1 SIRPB1 CD300A CD300A ICA1-2 ICA1-2 CUZD1 CUZD1 TMED10 TMED10 SIGLEC14 SIGLEC14 LHFPL2 LHFPL2 ANPEP ANPEP LAMP2 LAMP2 DOK3 DOK3 LOC104676073 LOC104676073 NFASC NFASC SPARC SPARC TRPM2 TRPM2 FRMPD3 FRMPD3 RAB3D RAB3D NCSTN NCSTN ATP8A1 ATP8A1 MOSPD2 MOSPD2 BSG BSG SERPINA5 SERPINA5 MANBA MANBA LPCAT1 LPCAT1 UBR4 UBR4 ENSRROP00000015460 ENSRROP00000015460 CEACAM1 CEACAM1 HYAL3 HYAL3 CYBB CYBB PTPRN2 PTPRN2 CD53 CD53 MFGE8 MFGE8 FLOT2 FLOT2 VPS13C VPS13C HGSNAT HGSNAT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKP1Plakophilin 1. (733 aa)
ALDH3B2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (504 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1337 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
CADPSCalcium dependent secretion activator. (1206 aa)
CKAP4Cytoskeleton associated protein 4. (597 aa)
SPAM1Hyaluronidase. (510 aa)
BRI3Brain protein I3. (103 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
NBEAL2Neurobeachin like 2. (2751 aa)
SYT1Synaptotagmin 1. (422 aa)
SPACA6Sperm acrosome associated 6. (324 aa)
SYT4Synaptotagmin 4. (425 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1154 aa)
SYNGR1Synaptogyrin. (234 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
SNAP23Synaptosome associated protein 23. (211 aa)
CD55CD55 molecule (Cromer blood group). (540 aa)
OLR1Oxidized low density lipoprotein receptor 1. (273 aa)
ENSRROP00000008301Galectin. (200 aa)
SIGLEC14-2Uncharacterized protein. (551 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1198 aa)
RAB31RAB31, member RAS oncogene family. (194 aa)
SYT9Synaptotagmin 9. (491 aa)
MCEMP1Mast cell expressed membrane protein 1. (187 aa)
TRIP11Thyroid hormone receptor interactor 11. (1980 aa)
MLECMalectin. (291 aa)
GPR84G protein-coupled receptor 84. (396 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
RHOFRas homolog family member F, filopodia associated. (211 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (756 aa)
STXBP5Syntaxin binding protein 5. (1151 aa)
TBC1D10CTBC1 domain family member 10C. (446 aa)
PLD1Phospholipase D1. (586 aa)
LOC104666756Uncharacterized protein. (189 aa)
CD9Tetraspanin. (227 aa)
RHOGUncharacterized protein. (191 aa)
DSC1Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (894 aa)
CD93CD93 molecule. (625 aa)
TEKT3Tektin 3. (490 aa)
DGAT1O-acyltransferase. (479 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2216 aa)
IZUMO1Izumo sperm-egg fusion 1. (350 aa)
BST1Bone marrow stromal cell antigen 1. (316 aa)
PLD1-2Uncharacterized protein. (57 aa)
ANO6Anoctamin. (931 aa)
TMBIM1Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (219 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
LOC104671192Galectin. (248 aa)
TMEM179BTransmembrane protein 179B. (219 aa)
CD58CD58 molecule. (250 aa)
FAM170BFamily with sequence similarity 170 member B. (283 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1049 aa)
NFAM1NFAT activating protein with ITAM motif 1. (271 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (398 aa)
LOC104675305IG domain-containing protein. (257 aa)
TARM1T cell-interacting, activating receptor on myeloid cells 1. (271 aa)
STING1Transmembrane protein 173. (379 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (135 aa)
SYTL4Synaptotagmin like 4. (672 aa)
EQTNEquatorin. (289 aa)
ENSRROP00000044300Uncharacterized protein. (180 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
CD63Tetraspanin. (238 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
DBHDopamine beta-hydroxylase. (572 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
ABCC4ATP binding cassette subfamily C member 4. (1325 aa)
TMEM95Transmembrane protein 95. (203 aa)
ITGB2Integrin beta. (769 aa)
ENSRROP00000041470Uncharacterized protein. (78 aa)
CD109CD109 molecule. (1449 aa)
CD46CD46 molecule. (399 aa)
STK10Serine/threonine kinase 10. (968 aa)
SLC15A4Solute carrier family 15 member 4. (527 aa)
ZG16Zymogen granule protein 16. (167 aa)
MOXD1Monooxygenase DBH like 1. (613 aa)
ACPPAcid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (418 aa)
ATP11BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1168 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
AZU1Azurocidin 1. (250 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (943 aa)
GLIPR1GLI pathogenesis related 1; Belongs to the CRISP family. (266 aa)
RAB4BUncharacterized protein. (213 aa)
TMEM184ATransmembrane protein 184A. (413 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
VNN1Vanin 1. (513 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
SELPSelectin P. (830 aa)
TEX101Testis expressed 101. (262 aa)
ICA1Islet cell autoantigen 1. (320 aa)
ADGRG3Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (551 aa)
CA4Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (312 aa)
GP2Glycoprotein 2. (534 aa)
ABCA13ATP binding cassette subfamily A member 13. (5057 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (289 aa)
RND2Rho family GTPase 2. (227 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
BST2Bone marrow stromal cell antigen 2. (182 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
CEACAM6Uncharacterized protein. (344 aa)
TSPAN14Tetraspanin. (280 aa)
SLC17A9Solute carrier family 17 member 9. (436 aa)
LGALS3Galectin. (252 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
ENSRROP00000035964Uncharacterized protein. (203 aa)
ATP8B4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1191 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
SLC30A5Solute carrier family 30 member 5. (766 aa)
SPACA1Sperm acrosome associated 1. (294 aa)
APLP2Amyloid beta precursor like protein 2. (757 aa)
CD44CD44 molecule (Indian blood group). (742 aa)
ENSRROP00000034704GOLD domain-containing protein. (105 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
SLC11A1Solute carrier family 11 member 1. (547 aa)
TMEM190Transmembrane protein 190. (177 aa)
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (510 aa)
LAMP1Lysosomal associated membrane protein 1. (412 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ABCA3ATP binding cassette subfamily A member 3. (1709 aa)
CCDC136Coiled-coil domain containing 136. (1154 aa)
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1786 aa)
CLEC5AC-type lectin domain containing 5A. (188 aa)
CLEC4CC-type lectin domain family 4 member C. (212 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
SYT2Synaptotagmin 2. (419 aa)
ENSRROP00000030240Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (104 aa)
RAB24RAB24, member RAS oncogene family. (154 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
VNN3Vanin 3. (273 aa)
SYCNSyncollin. (136 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (975 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
MGAMMaltase-glucoamylase. (1308 aa)
CD14CD14 molecule. (384 aa)
SYT5Synaptotagmin 5. (386 aa)
SCG3Secretogranin III. (468 aa)
SIRPAUncharacterized protein. (507 aa)
DSPDesmoplakin. (2871 aa)
DMBT1Deleted in malignant brain tumors 1. (1763 aa)
ANXA7Annexin. (488 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
ZPBPZona pellucida binding protein. (351 aa)
VPS13BVacuolar protein sorting 13 homolog B. (4022 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
PCDH7Protocadherin 7. (1146 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (278 aa)
RAB44RAB44, member RAS oncogene family. (1013 aa)
FCARFc fragment of IgA receptor. (178 aa)
PIGRPolymeric immunoglobulin receptor. (764 aa)
STOMStomatin. (288 aa)
DNAJC13DnaJ heat shock protein family (Hsp40) member C13. (2248 aa)
RAB27BRAB27B, member RAS oncogene family. (206 aa)
SIGLEC9Sialic acid binding Ig like lectin 9. (461 aa)
CYB561Cytochrome b561. (308 aa)
HVCN1Hydrogen voltage gated channel 1. (273 aa)
CD177Uncharacterized protein. (139 aa)
SCAMP1Secretory carrier-associated membrane protein. (309 aa)
LOC104668202Galectin-3. (248 aa)
CYSTM1Cysteine rich transmembrane module containing 1. (97 aa)
IGF2RInsulin like growth factor 2 receptor. (2486 aa)
DIAPH1Diaphanous related formin 1. (1238 aa)
SPACA3Sperm acrosome associated 3; Belongs to the glycosyl hydrolase 22 family. (213 aa)
ACRBPAcrosin binding protein. (543 aa)
MS4A3Membrane spanning 4-domains A3. (229 aa)
RAB26RAB26, member RAS oncogene family. (256 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1696 aa)
CD68CD68 molecule. (354 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (835 aa)
CLEC12AC-type lectin domain family 12 member A. (275 aa)
ENSRROP00000024302J domain-containing protein. (139 aa)
ENSRROP00000024205Uncharacterized protein. (176 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
PLA1APhospholipase A1 member A. (456 aa)
CYB5R1NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1191 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
FABP5FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (754 aa)
ENSRROP00000022810GOLD domain-containing protein. (100 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
TMEM225Transmembrane protein 225. (229 aa)
ENSRROP00000022469Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (129 aa)
SERPINB12Serpin family B member 12; Belongs to the serpin family. (425 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1311 aa)
CD33CD33 molecule. (360 aa)
EXOC3Exocyst complex component 3. (754 aa)
PHACTR2Phosphatase and actin regulator. (645 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1575 aa)
SIRPB1Uncharacterized protein. (397 aa)
CD300ACD300a molecule. (296 aa)
ICA1-2AH domain-containing protein. (101 aa)
CUZD1Uncharacterized protein. (607 aa)
TMED10Transmembrane p24 trafficking protein 10. (219 aa)
SIGLEC14Sialic acid binding Ig like lectin 14. (396 aa)
LHFPL2LHFPL tetraspan subfamily member 2. (228 aa)
ANPEPAminopeptidase. (980 aa)
LAMP2Lysosomal associated membrane protein 2. (411 aa)
DOK3Docking protein 3. (440 aa)
LOC104676073IGv domain-containing protein. (252 aa)
NFASCNeurofascin. (1059 aa)
SPARCSecreted protein acidic and cysteine rich. (341 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
FRMPD3FERM and PDZ domain containing 3. (1811 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
NCSTNNicastrin. (709 aa)
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1151 aa)
MOSPD2Motile sperm domain containing 2. (518 aa)
BSGBasigin (Ok blood group). (362 aa)
SERPINA5Serpin family A member 5; Belongs to the serpin family. (406 aa)
MANBAMannosidase beta. (879 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (486 aa)
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5182 aa)
ENSRROP00000015460Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
CEACAM1Uncharacterized protein. (525 aa)
HYAL3Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (1015 aa)
CD53Tetraspanin. (219 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (387 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (493 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3754 aa)
HGSNATHeparan-alpha-glucosaminide N-acetyltransferase. (612 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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