43 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC104678360	Nuclear receptor domain-containing protein. (231 aa)
	PTCH1	Patched 1. (1448 aa)
	SERPINF1	Serpin family F member 1; Belongs to the serpin family. (418 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (659 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	TNC	Tenascin C. (2201 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
	CYP19A1	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
	EAF2	ELL associated factor 2. (263 aa)
	HOXA11	Homeobox A11. (313 aa)
	FEM1B	Fem-1 homolog B. (627 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	PLAG1	PLAG1 zinc finger. (500 aa)
	LOC104668178	Uncharacterized protein. (392 aa)
	SHH	HH_signal domain-containing protein. (141 aa)
	FGFR2	Fibroblast growth factor receptor. (837 aa)
	RARA	Retinoic acid receptor alpha. (478 aa)
	HOXA13	Homeobox A13. (219 aa)
	FKBP4	Peptidylprolyl isomerase. (459 aa)
	PSAP	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (530 aa)
	GLI1	GLI family zinc finger 1. (1106 aa)
	RARG	Retinoic acid receptor gamma. (456 aa)
	NKX3-1	NK3 homeobox 1. (232 aa)
	HOXA10	Homeobox A10. (410 aa)
	AR	Uncharacterized protein. (523 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	CDKN1B	Cyclin dependent kinase inhibitor 1B. (198 aa)
	MMP2	Matrix metallopeptidase 2. (660 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
	HOXD13	Homeobox D13. (300 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	ID4	Inhibitor of DNA binding 4, HLH protein. (153 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	HOXB13	Homeobox B13. (284 aa)
	ENSRROP00000039864	Homeobox domain-containing protein. (142 aa)
	NOTCH1	Notch receptor 1. (2560 aa)
	WDR77	WD repeat domain 77. (342 aa)
	SERPINB5	Serpin family B member 5; Belongs to the serpin family. (375 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	CTNNB1	ENSRROP00000025864	ENSRROP00000030288	Uncharacterized protein.	Catenin beta 1.	0.777
AR	CYP19A1	ENSRROP00000025864	ENSRROP00000007646	Uncharacterized protein.	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	0.427
AR	FKBP4	ENSRROP00000025864	ENSRROP00000019068	Uncharacterized protein.	Peptidylprolyl isomerase.	0.715
AR	LOC104668178	ENSRROP00000025864	ENSRROP00000015607	Uncharacterized protein.	Uncharacterized protein.	0.484
AR	LOC104678360	ENSRROP00000025864	ENSRROP00000044141	Uncharacterized protein.	Nuclear receptor domain-containing protein.	0.574
AR	NKX3-1	ENSRROP00000025864	ENSRROP00000023369	Uncharacterized protein.	NK3 homeobox 1.	0.482
AR	PTEN	ENSRROP00000025864	ENSRROP00000014098	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.410
BMP4	CTNNB1	ENSRROP00000036929	ENSRROP00000030288	Bone morphogenetic protein 4.	Catenin beta 1.	0.421
BMP4	FGF10	ENSRROP00000036929	ENSRROP00000004602	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.568
BMP4	NOG	ENSRROP00000036929	ENSRROP00000004216	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.995
BMP4	PTCH1	ENSRROP00000036929	ENSRROP00000000063	Bone morphogenetic protein 4.	Patched 1.	0.433
BMP4	SHH	ENSRROP00000036929	ENSRROP00000015877	Bone morphogenetic protein 4.	HH_signal domain-containing protein.	0.598
CDKN1B	NOG	ENSRROP00000026767	ENSRROP00000004216	Cyclin dependent kinase inhibitor 1B.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.400
CDKN1B	PTEN	ENSRROP00000026767	ENSRROP00000014098	Cyclin dependent kinase inhibitor 1B.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.463
CDKN1B	TP63	ENSRROP00000026767	ENSRROP00000003748	Cyclin dependent kinase inhibitor 1B.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.431
CTNNB1	AR	ENSRROP00000030288	ENSRROP00000025864	Catenin beta 1.	Uncharacterized protein.	0.777
CTNNB1	BMP4	ENSRROP00000030288	ENSRROP00000036929	Catenin beta 1.	Bone morphogenetic protein 4.	0.421
CTNNB1	FGFR2	ENSRROP00000030288	ENSRROP00000017546	Catenin beta 1.	Fibroblast growth factor receptor.	0.467
CTNNB1	GLI1	ENSRROP00000030288	ENSRROP00000020996	Catenin beta 1.	GLI family zinc finger 1.	0.524
CTNNB1	LOC104668178	ENSRROP00000030288	ENSRROP00000015607	Catenin beta 1.	Uncharacterized protein.	0.777