STRINGSTRING
NECTIN1 NECTIN1 COL1A1 COL1A1 ITGB6 ITGB6 ATG4B ATG4B CCDC154 CCDC154 ITGB1BP1 ITGB1BP1 COL1A2 COL1A2 LGR4 LGR4 COMP COMP LTBP3 LTBP3 TGFB1 TGFB1 CER1 CER1 TMEM38B TMEM38B FAM83H FAM83H CLEC3B CLEC3B KLK4 KLK4 FGFR3 FGFR3 SLC24A3 SLC24A3 MMP13 MMP13 ENSRROP00000037464 ENSRROP00000037464 ENSRROP00000037082 ENSRROP00000037082 LOC104668685 LOC104668685 PKDCC PKDCC TSPEAR TSPEAR WDR72 WDR72 SBDS SBDS TUFT1 TUFT1 ERCC2 ERCC2 PTGS2 PTGS2 ANKH ANKH FGR FGR DMP1 DMP1 ENAM ENAM DDR2 DDR2 LOC104668684 LOC104668684 EIF2AK3 EIF2AK3 DSPP DSPP AMELX AMELX SPP1 SPP1 PTH1R PTH1R ALPL ALPL PHEX PHEX LOC104677212 LOC104677212 IGF1 IGF1 STATH STATH PHOSPHO1 PHOSPHO1 IFT80 IFT80 MEPE MEPE IBSP IBSP PTHLH PTHLH TCIRG1 TCIRG1 GATA1 GATA1 TFIP11 TFIP11 OTOL1 OTOL1 ENPP1 ENPP1 ZBTB40 ZBTB40 STIM1 STIM1 SNX10 SNX10 FBXL15 FBXL15 LOC104674202 LOC104674202 FGFR2 FGFR2 AMBN AMBN ENSRROP00000015696 ENSRROP00000015696 PPARA PPARA WNT11 WNT11 AXIN2 AXIN2 AMTN AMTN ODAM ODAM SLC20A1 SLC20A1 ECM1 ECM1 MINPP1 MINPP1 BMP2 BMP2 FAM20C FAM20C CNNM4 CNNM4 ZMPSTE24 ZMPSTE24 SP7 SP7 LOX LOX ATF4 ATF4 SRGN SRGN HACD1 HACD1 OTOP1 OTOP1 FAM20A FAM20A RSPO2 RSPO2 ASPN ASPN CYP27B1 CYP27B1 ROR2 ROR2 IFITM5 IFITM5 PTN PTN SLC24A4 SLC24A4 KLF10 KLF10 CEMP1 CEMP1 LOC104659307 LOC104659307 PHOSPHO2 PHOSPHO2 HIF1A HIF1A SBNO2 SBNO2 DUOX2 DUOX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (394 aa)
CCDC154Coiled-coil domain containing 154. (522 aa)
ITGB1BP1PID domain-containing protein. (154 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1069 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
TMEM38BTransmembrane protein 38B. (276 aa)
FAM83HFamily with sequence similarity 83 member H. (1254 aa)
CLEC3BC-type lectin domain family 3 member B. (202 aa)
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (254 aa)
FGFR3Fibroblast growth factor receptor. (803 aa)
SLC24A3Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (596 aa)
MMP13Matrix metallopeptidase 13. (503 aa)
ENSRROP00000037464Uncharacterized protein. (301 aa)
ENSRROP00000037082Uncharacterized protein. (222 aa)
LOC104668685Uncharacterized protein. (57 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (277 aa)
TSPEARThrombospondin type laminin G domain and EAR repeats. (669 aa)
WDR72WD_REPEATS_REGION domain-containing protein. (137 aa)
SBDSUncharacterized protein. (250 aa)
TUFT1Tuftelin 1. (390 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ANKHANKH inorganic pyrophosphate transport regulator. (502 aa)
FGRTyrosine-protein kinase. (529 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (506 aa)
ENAMEnamelin. (1140 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
LOC104668684Uncharacterized protein. (51 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
DSPPUncharacterized protein. (1263 aa)
AMELXAmelogenin X-linked. (205 aa)
SPP1Secreted phosphoprotein 1. (324 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
ALPLAlkaline phosphatase. (524 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)
LOC104677212Lipoxygenase domain-containing protein. (345 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (208 aa)
STATHStatherin. (62 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
IFT80Intraflagellar transport 80. (777 aa)
MEPEMatrix extracellular phosphoglycoprotein. (554 aa)
IBSPIntegrin binding sialoprotein. (317 aa)
PTHLHParathyroid hormone like hormone. (209 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
GATA1GATA binding protein 1. (413 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
OTOL1Otolin 1. (470 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (917 aa)
ZBTB40Zinc finger and BTB domain containing 40. (1239 aa)
STIM1Stromal interaction molecule 1. (785 aa)
SNX10Sorting nexin 10. (201 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
LOC104674202PID domain-containing protein. (184 aa)
FGFR2Fibroblast growth factor receptor. (837 aa)
AMBNAmeloblastin. (446 aa)
ENSRROP00000015696Uncharacterized protein. (52 aa)
PPARAPeroxisome proliferator activated receptor alpha. (398 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
AXIN2Axin 2. (843 aa)
AMTNAmelotin. (209 aa)
ODAMOdontogenic, ameloblast associated. (279 aa)
SLC20A1Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (492 aa)
ECM1Extracellular matrix protein 1. (540 aa)
MINPP1Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. (487 aa)
BMP2Bone morphogenetic protein 2. (470 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (506 aa)
CNNM4Cyclin and CBS domain divalent metal cation transport mediator 4. (775 aa)
ZMPSTE24Zinc metallopeptidase STE24. (515 aa)
SP7Sp7 transcription factor. (431 aa)
LOXLysyl oxidase. (417 aa)
ATF4Activating transcription factor 4. (351 aa)
SRGNSerglycin. (153 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa)
OTOP1Otopetrin 1. (610 aa)
FAM20AFAM20A golgi associated secretory pathway pseudokinase. (541 aa)
RSPO2R-spondin 2. (243 aa)
ASPNAsporin. (374 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
PTNPleiotrophin. (167 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
KLF10Kruppel like factor 10. (480 aa)
CEMP1Uncharacterized protein. (47 aa)
LOC104659307TB domain-containing protein. (166 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
SBNO2Strawberry notch homolog 2. (1236 aa)
DUOX2Dual oxidase 2. (1548 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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