45 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD160	CD160 molecule. (232 aa)
	TNFSF14	TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
	TNFRSF13C	TNF receptor superfamily member 13C. (167 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	CD81	Tetraspanin. (274 aa)
	EFNB2	Ephrin B2; Belongs to the ephrin family. (333 aa)
	CD28	CD28 molecule. (220 aa)
	ENSRROP00000042123	Uncharacterized protein. (251 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
	MAP3K8	Mitogen-activated protein kinase kinase kinase 8. (467 aa)
	EFNB3	Ephrin B3; Belongs to the ephrin family. (340 aa)
	TMIGD2	Transmembrane and immunoglobulin domain containing 2. (275 aa)
	CD5	CD5 molecule. (499 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	ICOS	Inducible T cell costimulator. (199 aa)
	TNFRSF14	TNF receptor superfamily member 14. (283 aa)
	ICOSLG	Uncharacterized protein. (275 aa)
	PDCD1LG2	Programmed cell death 1 ligand 2. (273 aa)
	LGALS1	Galectin. (135 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	ENSRROP00000021422	Uncharacterized protein. (534 aa)
	CARD11	Caspase recruitment domain family member 11. (1154 aa)
	SRC	Tyrosine-protein kinase. (540 aa)
	HHLA2	HERV-H LTR-associating 2. (419 aa)
	ENSRROP00000036200	Uncharacterized protein. (491 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	YES1	Tyrosine-protein kinase. (543 aa)
	ENSRROP00000017558	Uncharacterized protein. (78 aa)
	CD274	CD274 molecule. (290 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	EFNB1	Ephrin B1; Belongs to the ephrin family. (346 aa)
	LCK	Tyrosine-protein kinase. (561 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (845 aa)
	CD3E	CD3e molecule. (198 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSRROP00000011759	Uncharacterized protein. (274 aa)
	ENSRROP00000010437	Uncharacterized protein. (235 aa)
	CD24	Uncharacterized protein. (127 aa)
	CCL19	C-C motif chemokine. (98 aa)
	CD86	CD86 molecule. (329 aa)
	LYN	Tyrosine-protein kinase. (491 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	CD80	CD80 molecule. (288 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
	ENSRROP00000034614	Tyrosine-protein kinase. (465 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	CAV1	ENSRROP00000002071	ENSRROP00000024200	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.566
AKT1	CD28	ENSRROP00000002071	ENSRROP00000041237	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD28 molecule.	0.448
AKT1	CD80	ENSRROP00000002071	ENSRROP00000001520	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD80 molecule.	0.485
AKT1	CD86	ENSRROP00000002071	ENSRROP00000008396	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD86 molecule.	0.475
AKT1	CSK	ENSRROP00000002071	ENSRROP00000037903	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.475
AKT1	ENSRROP00000034614	ENSRROP00000002071	ENSRROP00000034614	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.700
AKT1	FYN	ENSRROP00000002071	ENSRROP00000018822	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.590
AKT1	LCK	ENSRROP00000002071	ENSRROP00000013457	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.520
AKT1	LYN	ENSRROP00000002071	ENSRROP00000006862	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.544
AKT1	MAP3K8	ENSRROP00000002071	ENSRROP00000042918	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 8.	0.953
AKT1	PIK3CA	ENSRROP00000002071	ENSRROP00000011898	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.982
AKT1	SRC	ENSRROP00000002071	ENSRROP00000019991	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.834
AKT1	VAV1	ENSRROP00000002071	ENSRROP00000013236	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Vav guanine nucleotide exchange factor 1.	0.654
AKT1	YES1	ENSRROP00000002071	ENSRROP00000018226	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.622
CARD11	CD28	ENSRROP00000021344	ENSRROP00000041237	Caspase recruitment domain family member 11.	CD28 molecule.	0.568
CAV1	AKT1	ENSRROP00000024200	ENSRROP00000002071	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.566
CAV1	CD81	ENSRROP00000024200	ENSRROP00000040804	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tetraspanin.	0.567
CAV1	CSK	ENSRROP00000024200	ENSRROP00000037903	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.492
CAV1	DPP4	ENSRROP00000024200	ENSRROP00000042771	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.664
CAV1	ENSRROP00000034614	ENSRROP00000024200	ENSRROP00000034614	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.513