24 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC104676775	Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
	CD3E	CD3e molecule. (198 aa)
	SASH3	SAM and SH3 domain containing 3. (380 aa)
	HAVCR2	Hepatitis A virus cellular receptor 2. (293 aa)
	CD86	CD86 molecule. (329 aa)
	IL1RAP	Interleukin 1 receptor accessory protein. (687 aa)
	IL33	Interleukin 33. (270 aa)
	GATA3	GATA binding protein 3. (444 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
	IRF4	Interferon regulatory factor 4. (450 aa)
	SLC7A5	Solute carrier family 7 member 5. (500 aa)
	FOXP3	Forkhead box P3. (454 aa)
	TNFSF4	TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
	EPX	Eosinophil peroxidase. (715 aa)
	NLRP3	NLR family pyrin domain containing 3. (1035 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
	IL20RB	Interleukin 20 receptor subunit beta. (311 aa)
	FCER1G	Fc fragment of IgE receptor Ig. (112 aa)
	CD28	CD28 molecule. (220 aa)
	HLA-E	Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
	RARA	Retinoic acid receptor alpha. (478 aa)
	CLECL1	Uncharacterized protein. (162 aa)
	SYK	Tyrosine-protein kinase. (635 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD28	CD3E	ENSRROP00000041237	ENSRROP00000013054	CD28 molecule.	CD3e molecule.	0.468
CD28	CD40LG	ENSRROP00000041237	ENSRROP00000035971	CD28 molecule.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.792
CD28	CD86	ENSRROP00000041237	ENSRROP00000008396	CD28 molecule.	CD86 molecule.	0.963
CD28	FOXP3	ENSRROP00000041237	ENSRROP00000029857	CD28 molecule.	Forkhead box P3.	0.625
CD28	HAVCR2	ENSRROP00000041237	ENSRROP00000008761	CD28 molecule.	Hepatitis A virus cellular receptor 2.	0.483
CD28	PRKCQ	ENSRROP00000041237	ENSRROP00000023574	CD28 molecule.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.601
CD28	TNFSF4	ENSRROP00000041237	ENSRROP00000030801	CD28 molecule.	TNF superfamily member 4; Belongs to the tumor necrosis factor family.	0.697
CD3E	CD28	ENSRROP00000013054	ENSRROP00000041237	CD3e molecule.	CD28 molecule.	0.468
CD3E	CD40LG	ENSRROP00000013054	ENSRROP00000035971	CD3e molecule.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.414
CD3E	CD86	ENSRROP00000013054	ENSRROP00000008396	CD3e molecule.	CD86 molecule.	0.454
CD3E	FOXP3	ENSRROP00000013054	ENSRROP00000029857	CD3e molecule.	Forkhead box P3.	0.459
CD3E	GATA3	ENSRROP00000013054	ENSRROP00000023250	CD3e molecule.	GATA binding protein 3.	0.408
CD3E	HAVCR2	ENSRROP00000013054	ENSRROP00000008761	CD3e molecule.	Hepatitis A virus cellular receptor 2.	0.415
CD3E	HLA-E	ENSRROP00000013054	ENSRROP00000039422	CD3e molecule.	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	0.478
CD3E	LOC104676775	ENSRROP00000013054	ENSRROP00000016350	CD3e molecule.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.478
CD3E	PRKCQ	ENSRROP00000013054	ENSRROP00000023574	CD3e molecule.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.421
CD3E	SYK	ENSRROP00000013054	ENSRROP00000020129	CD3e molecule.	Tyrosine-protein kinase.	0.972
CD40LG	CD28	ENSRROP00000035971	ENSRROP00000041237	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	CD28 molecule.	0.792
CD40LG	CD3E	ENSRROP00000035971	ENSRROP00000013054	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	CD3e molecule.	0.414
CD40LG	CD86	ENSRROP00000035971	ENSRROP00000008396	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	CD86 molecule.	0.756