STRINGSTRING
TYK2 TYK2 JAK2 JAK2 IL12RB1 IL12RB1 IL23R IL23R IL18 IL18 IL23A IL23A HLA-E HLA-E IL15 IL15 LOC104676775 LOC104676775 STAT5B STAT5B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TYK2Tyrosine-protein kinase. (1187 aa)
JAK2Tyrosine-protein kinase. (1094 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (661 aa)
IL23RInterleukin 23 receptor. (629 aa)
IL18Interleukin 18. (211 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
LOC104676775Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.