STRINGSTRING
PML PML CAVIN3 CAVIN3 PPARGC1A PPARGC1A MC3R MC3R ID2 ID2 PASD1 PASD1 SIRT6 SIRT6 HUWE1 HUWE1 ARNTL2 ARNTL2 OGT OGT PRMT5 PRMT5 ATF4 ATF4 NRIP1 NRIP1 ENSRROP00000007230 ENSRROP00000007230 KDM8 KDM8 HDAC3 HDAC3 ID3 ID3 NR1D1 NR1D1 EGR1 EGR1 RORA RORA DRD2 DRD2 LGR4 LGR4 PPP1CC PPP1CC PER3 PER3 KDM5A KDM5A TOP1 TOP1 ENSRROP00000039638 ENSRROP00000039638 NR0B2 NR0B2 CSNK1D CSNK1D HNRNPU HNRNPU USP2 USP2 CARTPT CARTPT ID4 ID4 NUDT12 NUDT12 RORC RORC NCOA2 NCOA2 MAGED1 MAGED1 CSNK1E CSNK1E ZFHX3 ZFHX3 PPP1CA PPP1CA BHLHE40 BHLHE40 MYBBP1A MYBBP1A ENSRROP00000030430 ENSRROP00000030430 LOC104677352 LOC104677352 BHLHE41 BHLHE41 PPP1CB PPP1CB RAI1 RAI1 NPAS2 NPAS2 ARNTL ARNTL CLOCK CLOCK NAMPT NAMPT CRY1 CRY1 SIRT1 SIRT1 ENSRROP00000019405 ENSRROP00000019405 ID1 ID1 GFPT1 GFPT1 HDAC2 HDAC2 RBM4B RBM4B RBM4 RBM4 NGFR NGFR PER1 PER1 NOCT NOCT HDAC1 HDAC1 PPARA PPARA CRY2 CRY2 CIART CIART RELB RELB MYCBP2 MYCBP2 PER2 PER2 ZPBP2 ZPBP2 KDM2A KDM2A ENSRROP00000005469 ENSRROP00000005469 MTA1 MTA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PMLPromyelocytic leukemia. (882 aa)
CAVIN3Caveolae associated protein 3. (293 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
MC3RMelanocortin 3 receptor. (323 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
PASD1PAS domain containing repressor 1. (687 aa)
SIRT6Sirtuin 6. (355 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4423 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (622 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
ATF4Activating transcription factor 4. (351 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
ENSRROP00000007230Uncharacterized protein. (193 aa)
KDM8Lysine demethylase 8. (454 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa)
RORARAR related orphan receptor A. (555 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
PER3Period circadian regulator 3. (1178 aa)
KDM5ALysine demethylase 5A. (1690 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
ENSRROP00000039638Endo/exonuclease/phosphatase domain-containing protein. (403 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
CSNK1DCasein kinase 1 delta. (406 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (806 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (635 aa)
CARTPTCART prepropeptide. (116 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (153 aa)
NUDT12Nudix hydrolase 12. (462 aa)
RORCRAR related orphan receptor C. (519 aa)
NCOA2Nuclear receptor coactivator. (1475 aa)
MAGED1MAGE family member D1. (834 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
ZFHX3Zinc finger homeobox 3. (3704 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
MYBBP1AMYB binding protein 1a. (1340 aa)
ENSRROP00000030430Uncharacterized protein. (297 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
BHLHE41Uncharacterized protein. (334 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (373 aa)
RAI1Retinoic acid induced 1. (1910 aa)
NPAS2Neuronal PAS domain protein 2. (824 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
CLOCKClock circadian regulator. (847 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (499 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
SIRT1Sirtuin 1. (746 aa)
ENSRROP00000019405Hist_deacetyl domain-containing protein. (352 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
RBM4BRNA binding motif protein 4B. (359 aa)
RBM4Uncharacterized protein. (193 aa)
NGFRNerve growth factor receptor. (427 aa)
PER1Period circadian regulator 1. (1292 aa)
NOCTEndo/exonuclease/phosphatase domain-containing protein. (431 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
PPARAPeroxisome proliferator activated receptor alpha. (398 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
CIARTCircadian associated repressor of transcription. (385 aa)
RELBRELB proto-oncogene, NF-kB subunit. (541 aa)
MYCBP2MYC binding protein 2. (4751 aa)
PER2Period circadian regulator 2. (1253 aa)
ZPBP2Zona pellucida binding protein 2. (337 aa)
KDM2ALysine demethylase 2A. (1162 aa)
ENSRROP00000005469Uncharacterized protein. (53 aa)
MTA1Metastasis associated 1. (697 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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