STRINGSTRING
RBBP7 RBBP7 ENSRROP00000035521 ENSRROP00000035521 PRMT5 PRMT5 WTAP WTAP ENSRROP00000045686 ENSRROP00000045686 SNRPG SNRPG RBM15 RBM15 TRMT6 TRMT6 ENSRROP00000044639 ENSRROP00000044639 METTL14 METTL14 PAXIP1 PAXIP1 CBX5 CBX5 TRMT61B TRMT61B RNMT RNMT WDR4 WDR4 LOC104665116 LOC104665116 MAX MAX SETD1A SETD1A HCFC2 HCFC2 KMT2A KMT2A PRMT1 PRMT1 ENSRROP00000031010 ENSRROP00000031010 PRPF31 PRPF31 LOC104658081 LOC104658081 KAT8 KAT8 E2F6 E2F6 VIRMA VIRMA METTL1 METTL1 RUVBL1 RUVBL1 WDR82 WDR82 ENSRROP00000026765 ENSRROP00000026765 ENSRROP00000044391 ENSRROP00000044391 RBBP5 RBBP5 KMT2C KMT2C UTY UTY CLNS1A CLNS1A MCRS1 MCRS1 BOD1L1 BOD1L1 INO80C INO80C KDM6B KDM6B ASH2L ASH2L RUVBL2 RUVBL2 NCOA6 NCOA6 WDR77 WDR77 ENSRROP00000041105 ENSRROP00000041105 LOC104672435 LOC104672435 DYDC2 DYDC2 MGA MGA SUZ12 SUZ12 ENSRROP00000026439 ENSRROP00000026439 SENP3 SENP3 AEBP2 AEBP2 EZH1 EZH1 ENSRROP00000025753 ENSRROP00000025753 RIOK1 RIOK1 MEN1 MEN1 ENSRROP00000024732 ENSRROP00000024732 SNRPB SNRPB KMT2D KMT2D ENSRROP00000023133 ENSRROP00000023133 KANSL1 KANSL1 RBBP4 RBBP4 SNRPD2 SNRPD2 KMT2B KMT2B ENSRROP00000020651 ENSRROP00000020651 EZH2 EZH2 PHF19 PHF19 EED EED ENSRROP00000017857 ENSRROP00000017857 HDAC2 HDAC2 SNRPG-2 SNRPG-2 ENSRROP00000017477 ENSRROP00000017477 ERH ERH HSD17B10 HSD17B10 CBLL1 CBLL1 LOC104657043 LOC104657043 RAMAC RAMAC SNRPE SNRPE HDAC9 HDAC9 TAF1 TAF1 C17orf49 C17orf49 ENSRROP00000014292 ENSRROP00000014292 MTF2 MTF2 SNRPD3 SNRPD3 SNRPF SNRPF LOC104672089 LOC104672089 ZNF335 ZNF335 KDM6A KDM6A METTL3 METTL3 ENSRROP00000010290 ENSRROP00000010290 LOC104657669 LOC104657669 CXXC1 CXXC1 N6AMT1 N6AMT1 SNRPD1 SNRPD1 PELP1 PELP1 PAGR1 PAGR1 PHF20 PHF20 LOC104657389 LOC104657389 EPOP EPOP ZC3H13 ZC3H13 LOC104674542 LOC104674542 RBM15B RBM15B WDR5B WDR5B PRDM4 PRDM4 SETD1B SETD1B CHD8 CHD8 LAS1L LAS1L LOC104671355 LOC104671355 HCFC1 HCFC1 TAF6 TAF6 RNF2 RNF2 DPY30 DPY30 DYDC1 DYDC1 TAF4 TAF4 WDR5 WDR5 JARID2 JARID2 TEX10 TEX10 TRMT61A TRMT61A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
ENSRROP00000035521WD_REPEATS_REGION domain-containing protein. (356 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
WTAPWT1 associated protein. (319 aa)
ENSRROP00000045686Uncharacterized protein. (153 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
RBM15RNA binding motif protein 15. (977 aa)
TRMT6tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. (497 aa)
ENSRROP00000044639Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (72 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)
PAXIP1PAX interacting protein 1. (1075 aa)
CBX5Uncharacterized protein. (191 aa)
TRMT61BtRNA methyltransferase 61B. (483 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (476 aa)
WDR4tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (466 aa)
LOC104665116Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (255 aa)
MAXMYC associated factor X. (160 aa)
SETD1AUncharacterized protein. (1389 aa)
HCFC2Host cell factor C2. (792 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3914 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
ENSRROP00000031010Uncharacterized protein. (273 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
LOC104658081RING-type domain-containing protein. (290 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (469 aa)
E2F6E2F transcription factor 6. (281 aa)
VIRMAVir like m6A methyltransferase associated. (1843 aa)
METTL1tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (301 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
WDR82WD repeat domain 82. (313 aa)
ENSRROP00000026765Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
ENSRROP00000044391WD_REPEATS_REGION domain-containing protein. (379 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (548 aa)
KMT2CLysine methyltransferase 2C. (4916 aa)
UTYUbiquitously transcribed tetratricopeptide repeat containing, Y-linked. (1450 aa)
CLNS1AUncharacterized protein. (237 aa)
MCRS1Microspherule protein 1. (475 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2978 aa)
INO80CINO80 complex subunit C. (228 aa)
KDM6BLysine demethylase 6B. (1682 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (572 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
NCOA6Nuclear receptor coactivator 6. (2069 aa)
WDR77WD repeat domain 77. (342 aa)
ENSRROP00000041105MTS domain-containing protein. (194 aa)
LOC104672435Uncharacterized protein. (180 aa)
DYDC2DPY30 domain containing 2. (190 aa)
MGAMAX dimerization protein MGA. (3069 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
ENSRROP00000026439WD_REPEATS_REGION domain-containing protein. (363 aa)
SENP3ULP_PROTEASE domain-containing protein. (580 aa)
AEBP2AE binding protein 2. (516 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
ENSRROP00000025753Sm domain-containing protein. (56 aa)
RIOK1Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (567 aa)
MEN1Menin 1. (610 aa)
ENSRROP00000024732Uncharacterized protein. (252 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
KMT2DLysine methyltransferase 2D. (5538 aa)
ENSRROP00000023133Uncharacterized protein. (235 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (674 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
KMT2BLysine methyltransferase 2B. (2642 aa)
ENSRROP00000020651Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (67 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (737 aa)
PHF19PHD finger protein 19. (599 aa)
EEDEmbryonic ectoderm development. (466 aa)
ENSRROP00000017857Uncharacterized protein. (67 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
SNRPG-2Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
ENSRROP00000017477Uncharacterized protein. (80 aa)
ERHEnhancer of rudimentary homolog; May have a role in the cell cycle. (104 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
CBLL1Cbl proto-oncogene like 1. (491 aa)
LOC104657043Uncharacterized protein. (229 aa)
RAMACUncharacterized protein. (118 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)
TAF1TATA-box binding protein associated factor 1. (1196 aa)
C17orf49Uncharacterized protein. (284 aa)
ENSRROP00000014292Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
MTF2Metal response element binding transcription factor 2. (593 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SNRPFSm domain-containing protein. (127 aa)
LOC104672089Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (109 aa)
ZNF335Zinc finger protein 335. (1379 aa)
KDM6ALysine demethylase 6A. (1453 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
ENSRROP00000010290Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (66 aa)
LOC104657669RING-type domain-containing protein. (321 aa)
CXXC1CXXC finger protein 1. (655 aa)
N6AMT1N-6 adenine-specific DNA methyltransferase 1. (214 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (130 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1066 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (254 aa)
PHF20PHD finger protein 20. (1010 aa)
LOC104657389Sm domain-containing protein. (86 aa)
EPOPElongin BC and polycomb repressive complex 2 associated protein. (379 aa)
ZC3H13Zinc finger CCCH-type containing 13. (1555 aa)
LOC104674542Uncharacterized protein. (264 aa)
RBM15BRNA binding motif protein 15B. (890 aa)
WDR5BWD repeat domain 5B. (330 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa)
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1888 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2582 aa)
LAS1LLAS1 like, ribosome biogenesis factor. (738 aa)
LOC104671355Uncharacterized protein. (199 aa)
HCFC1Host cell factor C1. (2080 aa)
TAF6TATA-box binding protein associated factor 6. (738 aa)
RNF2RING-type domain-containing protein. (336 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
DYDC1DPY30 domain containing 1. (177 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
WDR5WD repeat domain 5. (342 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1246 aa)
TEX10Testis expressed 10. (914 aa)
TRMT61AtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. (289 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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