Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACVR2B | BMP10 | ENSRROP00000026676 | ENSRROP00000032265 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 10. | 0.689 |
| ACVR2B | SMAD1 | ENSRROP00000026676 | ENSRROP00000038071 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.637 |
| ACVR2B | SMAD2 | ENSRROP00000026676 | ENSRROP00000023441 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.657 |
| ACVR2B | TGFBR2 | ENSRROP00000026676 | ENSRROP00000003400 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.403 |
| AR | CYP19A1 | ENSRROP00000025864 | ENSRROP00000007646 | Uncharacterized protein. | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.427 |
| AR | LEP | ENSRROP00000025864 | ENSRROP00000018370 | Uncharacterized protein. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.415 |
| AR | LOC104668178 | ENSRROP00000025864 | ENSRROP00000015607 | Uncharacterized protein. | Uncharacterized protein. | 0.484 |
| AR | LOC104678360 | ENSRROP00000025864 | ENSRROP00000044141 | Uncharacterized protein. | Nuclear receptor domain-containing protein. | 0.574 |
| AR | PTEN | ENSRROP00000025864 | ENSRROP00000014098 | Uncharacterized protein. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.410 |
| ATF2 | MAPK11 | ENSRROP00000009970 | ENSRROP00000043382 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | Mitogen-activated protein kinase. | 0.863 |
| BCL2 | IL7 | ENSRROP00000035252 | ENSRROP00000009696 | BCL2 apoptosis regulator. | Interleukin 7. | 0.400 |
| BCL2 | LEP | ENSRROP00000035252 | ENSRROP00000018370 | BCL2 apoptosis regulator. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.565 |
| BCL2 | LOC104678360 | ENSRROP00000035252 | ENSRROP00000044141 | BCL2 apoptosis regulator. | Nuclear receptor domain-containing protein. | 0.536 |
| BCL2 | PTEN | ENSRROP00000035252 | ENSRROP00000014098 | BCL2 apoptosis regulator. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.505 |
| BMP10 | ACVR2B | ENSRROP00000032265 | ENSRROP00000026676 | Bone morphogenetic protein 10. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.689 |
| BMP10 | TGFBR2 | ENSRROP00000032265 | ENSRROP00000003400 | Bone morphogenetic protein 10. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.449 |
| CER1 | WNT2 | ENSRROP00000039572 | ENSRROP00000003994 | Cerberus 1, DAN family BMP antagonist. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.904 |
| COMP | MATN1 | ENSRROP00000041345 | ENSRROP00000000049 | Cartilage oligomeric matrix protein. | Matrilin 1. | 0.443 |
| COMP | MMP13 | ENSRROP00000041345 | ENSRROP00000037872 | Cartilage oligomeric matrix protein. | Matrix metallopeptidase 13. | 0.470 |
| COMP | THBS3 | ENSRROP00000041345 | ENSRROP00000011282 | Cartilage oligomeric matrix protein. | Thrombospondin 3. | 0.481 |
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