STRINGSTRING
ANKRD33 ANKRD33 SELENON SELENON EGR1 EGR1 NOTCH1 NOTCH1 PAX5 PAX5 MAFF MAFF EGR2 EGR2 MYLK2 MYLK2 KLF5 KLF5 KLHL40 KLHL40 COPS2 COPS2 MYF5 MYF5 MYF6 MYF6 BCL9L BCL9L KRAS KRAS CITED2 CITED2 NUPR1 NUPR1 SOX8 SOX8 GTF3C5 GTF3C5 FOS FOS MYOD1 MYOD1 WNT3A WNT3A VAX1 VAX1 ZNF689 ZNF689 HLF HLF MYOG MYOG SMYD1 SMYD1 ATF3 ATF3 BCL9 BCL9 HEYL HEYL RB1 RB1 ENSRROP00000023205 ENSRROP00000023205 LOC104660272 LOC104660272 EOMES EOMES MEGF10 MEGF10 CDON CDON ASB2 ASB2 SHH SHH HIVEP3 HIVEP3 KLHL41 KLHL41 ANKRD33B ANKRD33B EMD EMD ENSRROP00000009442 ENSRROP00000009442 NR4A1 NR4A1 LOC104655511 LOC104655511 SIX4 SIX4 LEMD2 LEMD2 DMRTA2 DMRTA2 PHOX2B PHOX2B HMG20B HMG20B ANKRD1 ANKRD1 MEF2D MEF2D BTG2 BTG2 SAP30 SAP30 BARX2 BARX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANKRD33Ankyrin repeat domain 33. (450 aa)
SELENONSelenoprotein N. (553 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa)
NOTCH1Notch receptor 1. (2560 aa)
PAX5Paired box 5. (391 aa)
MAFFMAF bZIP transcription factor F. (164 aa)
EGR2Early growth response 2. (476 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
KLF5Kruppel like factor 5. (457 aa)
KLHL40Kelch like family member 40. (621 aa)
COPS2COP9 signalosome subunit 2. (403 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (242 aa)
BCL9LBCL9 like. (1500 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
SOX8SRY-box transcription factor 8. (425 aa)
GTF3C5General transcription factor IIIC subunit 5. (528 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
VAX1Homeobox domain-containing protein. (186 aa)
ZNF689Zinc finger protein 689. (500 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
MYOGMyogenin. (249 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
ATF3Activating transcription factor 3. (201 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
RB1RB transcriptional corepressor 1. (929 aa)
ENSRROP00000023205LEM domain-containing protein. (219 aa)
LOC104660272Fork-head domain-containing protein. (213 aa)
EOMESEomesodermin. (706 aa)
MEGF10Multiple EGF like domains 10. (1033 aa)
CDONCell adhesion associated, oncogene regulated. (1287 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (638 aa)
SHHHH_signal domain-containing protein. (141 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2406 aa)
KLHL41Kelch like family member 41. (606 aa)
ANKRD33BAnkyrin repeat domain 33B. (512 aa)
EMDLEM domain-containing protein. (251 aa)
ENSRROP00000009442Uncharacterized protein. (179 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (670 aa)
LOC104655511Uncharacterized protein. (196 aa)
SIX4SIX homeobox 4. (780 aa)
LEMD2LEM domain containing 2. (416 aa)
DMRTA2DMRT like family A2. (540 aa)
PHOX2BPaired like homeobox 2B. (259 aa)
HMG20BHigh mobility group 20B. (318 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
SAP30Sin3A associated protein 30. (124 aa)
BARX2BARX homeobox 2. (279 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.