(30 nodes) Positive regulation of activated T cell proliferation network (Rhinopithecus roxellana)

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Your Input:
	PPP3CA	Serine/threonine-protein phosphatase. (417 aa)
	IL23A	Interleukin 23 subunit alpha. (189 aa)
	IL18	Interleukin 18. (211 aa)
	IL23R	Interleukin 23 receptor. (629 aa)
	TNFSF9	TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
	ENSRROP00000032658	KH type-2 domain-containing protein. (143 aa)
	LOC104668444	Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (251 aa)
	TMIGD2	Transmembrane and immunoglobulin domain containing 2. (275 aa)
	SLAMF1	Signaling lymphocytic activation molecule family member 1. (357 aa)
	ENSRROP00000026782	KH type-2 domain-containing protein. (133 aa)
	ICOSLG	Uncharacterized protein. (275 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (208 aa)
	IL27RA	Interleukin 27 receptor subunit alpha. (636 aa)
	AGER	Advanced glycosylation end-product specific receptor. (403 aa)
	HHLA2	HERV-H LTR-associating 2. (419 aa)
	ENSRROP00000017761	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (269 aa)
	ENSRROP00000017558	Uncharacterized protein. (78 aa)
	STAT5B	Signal transducer and activator of transcription. (787 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	IGF2	Insulin like growth factor 2. (236 aa)
	CD24	Uncharacterized protein. (127 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
	IL12RB1	Interleukin 12 receptor subunit beta 1. (661 aa)
	ENSRROP00000006428	Uncharacterized protein. (70 aa)
	JAK3	Tyrosine-protein kinase. (1124 aa)
	ENSRROP00000003001	Uncharacterized protein. (93 aa)
	RPS3	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	IGFBP2	Insulin like growth factor binding protein 2. (325 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD24	ENSRROP00000017558	ENSRROP00000009935	ENSRROP00000017558	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSRROP00000017558	CD24	ENSRROP00000017558	ENSRROP00000009935	Uncharacterized protein.	Uncharacterized protein.	0.900
HHLA2	TMIGD2	ENSRROP00000019854	ENSRROP00000032141	HERV-H LTR-associating 2.	Transmembrane and immunoglobulin domain containing 2.	0.708
HHLA2	TNFSF9	ENSRROP00000019854	ENSRROP00000040523	HERV-H LTR-associating 2.	TNF superfamily member 9; Belongs to the tumor necrosis factor family.	0.510
ICOSLG	TNFSF9	ENSRROP00000026040	ENSRROP00000040523	Uncharacterized protein.	TNF superfamily member 9; Belongs to the tumor necrosis factor family.	0.503
IGF1	IGF2	ENSRROP00000025479	ENSRROP00000010133	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor 2.	0.975
IGF1	IGFBP2	ENSRROP00000025479	ENSRROP00000000528	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 2.	0.935
IGF2	IGF1	ENSRROP00000010133	ENSRROP00000025479	Insulin like growth factor 2.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.975
IGF2	IGFBP2	ENSRROP00000010133	ENSRROP00000000528	Insulin like growth factor 2.	Insulin like growth factor binding protein 2.	0.896
IGFBP2	IGF1	ENSRROP00000000528	ENSRROP00000025479	Insulin like growth factor binding protein 2.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.935
IGFBP2	IGF2	ENSRROP00000000528	ENSRROP00000010133	Insulin like growth factor binding protein 2.	Insulin like growth factor 2.	0.896
IL12RB1	IL2	ENSRROP00000006429	ENSRROP00000009106	Interleukin 12 receptor subunit beta 1.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.785
IL12RB1	IL23A	ENSRROP00000006429	ENSRROP00000045259	Interleukin 12 receptor subunit beta 1.	Interleukin 23 subunit alpha.	0.989
IL12RB1	IL23R	ENSRROP00000006429	ENSRROP00000041163	Interleukin 12 receptor subunit beta 1.	Interleukin 23 receptor.	0.994
IL12RB1	IL27RA	ENSRROP00000006429	ENSRROP00000025387	Interleukin 12 receptor subunit beta 1.	Interleukin 27 receptor subunit alpha.	0.646
IL12RB1	JAK3	ENSRROP00000006429	ENSRROP00000004608	Interleukin 12 receptor subunit beta 1.	Tyrosine-protein kinase.	0.889
IL18	IL2	ENSRROP00000042235	ENSRROP00000009106	Interleukin 18.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.664
IL18	PYCARD	ENSRROP00000042235	ENSRROP00000039913	Interleukin 18.	PYD and CARD domain containing.	0.959
IL2	IL12RB1	ENSRROP00000009106	ENSRROP00000006429	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Interleukin 12 receptor subunit beta 1.	0.785
IL2	IL18	ENSRROP00000009106	ENSRROP00000042235	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Interleukin 18.	0.664