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| | ANP32E | Acidic nuclear phosphoprotein 32 family member E. (267 aa) |
| | DEK | SAP domain-containing protein. (375 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | ENSRROP00000036642 | Phorbol-ester/DAG-type domain-containing protein. (57 aa) |
| | RESF1 | Retroelement silencing factor 1. (1748 aa) |
| | BAZ2A | Bromodomain adjacent to zinc finger domain 2A. (1909 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1441 aa) |
| | CHD6 | Chromodomain helicase DNA binding protein 6. (1457 aa) |
| | PHC3 | Polyhomeotic homolog 3. (983 aa) |
| | LOC104661278 | Uncharacterized protein. (307 aa) |
| | PHF10 | PHD finger protein 10. (497 aa) |
| | SRCAP | Uncharacterized protein. (3230 aa) |
| | NAP1L4 | Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family. (386 aa) |
| | ENSRROP00000035521 | WD_REPEATS_REGION domain-containing protein. (356 aa) |
| | CBX1 | Chromobox 1. (261 aa) |
| | GRWD1 | Glutamate rich WD repeat containing 1. (445 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1968 aa) |
| | CHD2 | Uncharacterized protein. (1828 aa) |
| | PWWP2A | PWWP domain containing 2A. (755 aa) |
| | ENSRROP00000034976 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (121 aa) |
| | CBX5 | Uncharacterized protein. (191 aa) |
| | PHF1 | PHD finger protein 1. (567 aa) |
| | ENSRROP00000033942 | Uncharacterized protein. (349 aa) |
| | CDYL2 | Chromodomain Y like 2. (504 aa) |
| | STAT1 | Signal transducer and activator of transcription. (787 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | ZZEF1 | Zinc finger ZZ-type and EF-hand domain containing 1. (2962 aa) |
| | ING4 | Inhibitor of growth protein. (252 aa) |
| | NCAPD2 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1399 aa) |
| | CDYL | Chromodomain Y like. (563 aa) |
| | KMT5C | Lysine methyltransferase 5C. (461 aa) |
| | THAP7 | THAP domain containing 7. (309 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | SFMBT1 | Scm like with four mbt domains 1. (870 aa) |
| | NCAPD3 | Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1503 aa) |
| | ENSRROP00000032185 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (253 aa) |
| | ENSRROP00000032123 | Uncharacterized protein. (305 aa) |
| | MORC4 | MORC family CW-type zinc finger 4. (937 aa) |
| | ENSRROP00000031868 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (236 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (677 aa) |
| | CD1D | CD1d molecule. (337 aa) |
| | MBTD1 | Mbt domain containing 1. (628 aa) |
| | DPF3 | Double PHD fingers 3. (412 aa) |
| | USP16 | Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (826 aa) |
| | ENSRROP00000031050 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (241 aa) |
| | ENSRROP00000030506 | Uncharacterized protein. (164 aa) |
| | STPG1 | Sperm tail PG-rich repeat containing 1. (334 aa) |
| | SPTY2D1 | SPT2 chromatin protein domain containing 1. (685 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (554 aa) |
| | ENSRROP00000029707 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (64 aa) |
| | KAT8 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (469 aa) |
| | HINFP | Histone H4 transcription factor. (517 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (341 aa) |
| | PHC1 | Polyhomeotic homolog 1. (1005 aa) |
| | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9. (259 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (405 aa) |
| | PHF2 | PHD finger protein 2. (1102 aa) |
| | HDGFL2 | HDGF like 2. (656 aa) |
| | ZZZ3 | Uncharacterized protein. (903 aa) |
| | ENSRROP00000028142 | Uncharacterized protein. (153 aa) |
| | YEATS4 | YEATS domain containing 4. (227 aa) |
| | CHD1 | Chromodomain helicase DNA binding protein 1. (1712 aa) |
| | ZCWPW2 | Zinc finger CW-type and PWWP domain containing 2. (356 aa) |
| | ENSRROP00000000820 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa) |
| | ENSRROP00000000878 | Uncharacterized protein. (111 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (963 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | MCM3AP | Minichromosome maintenance complex component 3 associated protein. (1980 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1976 aa) |
| | SPIN4 | Spindlin family member 4. (249 aa) |
| | ENSRROP00000002307 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (290 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2998 aa) |
| | ENSRROP00000002793 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (250 aa) |
| | ASF1A | Anti-silencing function 1A histone chaperone. (204 aa) |
| | BRD2 | Uncharacterized protein. (836 aa) |
| | WDR5B | WD repeat domain 5B. (330 aa) |
| | PKN1 | Protein kinase N1. (965 aa) |
| | LOC104682414 | WD_REPEATS_REGION domain-containing protein. (489 aa) |
| | ENSRROP00000004512 | Uncharacterized protein. (95 aa) |
| | MLLT6 | MLLT6, PHD finger containing. (1404 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1327 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1570 aa) |
| | PRMT6 | Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa) |
| | HPF1 | Histone PARylation factor 1. (346 aa) |
| | ENSRROP00000005693 | Uncharacterized protein. (250 aa) |
| | PHF8 | PHD finger protein 8. (1098 aa) |
| | TSPYL2 | TSPY like 2; Belongs to the nucleosome assembly protein (NAP) family. (495 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (788 aa) |
| | SHISA4 | Shisa family member 4. (197 aa) |
| | LOC104660852 | Cyclin-dependent kinases regulatory subunit 1. (79 aa) |
| | SAP30L | SAP30 like. (188 aa) |
| | NASP | Nuclear autoantigenic sperm protein. (787 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | LOC104659416 | Uncharacterized protein. (258 aa) |
| | NAP1L1 | Nucleosome assembly protein 1 like 1; Belongs to the nucleosome assembly protein (NAP) family. (391 aa) |
| | KDM4A | Uncharacterized protein. (1064 aa) |
| | VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) |
| | KDM8 | Lysine demethylase 8. (454 aa) |
| | SCML4 | Scm polycomb group protein like 4. (414 aa) |
| | MORC3 | MORC family CW-type zinc finger 3. (939 aa) |
| | CHAF1B | Chromatin assembly factor 1 subunit B. (560 aa) |
| | CBX4 | Chromobox 4. (546 aa) |
| | ATRX | Uncharacterized protein. (164 aa) |
| | ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1. (651 aa) |
| | LOC104663422 | Uncharacterized protein. (297 aa) |
| | SAMD11 | Sterile alpha motif domain containing 11. (695 aa) |
| | ENSRROP00000008345 | Chromo domain-containing protein. (147 aa) |
| | ENSRROP00000008819 | Uncharacterized protein. (130 aa) |
| | GLYR1 | Glyoxylate reductase 1 homolog. (557 aa) |
| | COPRS | Coordinator of PRMT5 and differentiation stimulator. (172 aa) |
| | ENSRROP00000008956 | Uncharacterized protein. (277 aa) |
| | ENSRROP00000009018 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (327 aa) |
| | NAP1L5 | Nucleosome assembly protein 1 like 5; Belongs to the nucleosome assembly protein (NAP) family. (160 aa) |
| | LOC104681669 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (260 aa) |
| | LOC104661434 | Uncharacterized protein. (271 aa) |
| | ENSRROP00000009396 | Uncharacterized protein. (152 aa) |
| | SCML1 | Scm polycomb group protein like 1. (328 aa) |
| | HIRA | Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1095 aa) |
| | ANP32A | Acidic nuclear phosphoprotein 32 family member A. (249 aa) |
| | TSPYL5 | TSPY like 5; Belongs to the nucleosome assembly protein (NAP) family. (286 aa) |
| | LOC104653987 | Uncharacterized protein. (152 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2014 aa) |
| | MPND | MPN domain containing. (502 aa) |
| | SPIN1 | Spindlin 1. (262 aa) |
| | ING3 | Inhibitor of growth protein. (418 aa) |
| | SETD5 | SET domain containing 5. (1462 aa) |
| | JAK2 | Tyrosine-protein kinase. (1094 aa) |
| | DNAJC2 | DnaJ heat shock protein family (Hsp40) member C2. (621 aa) |
| | NPM3 | Nucleophosmin/nucleoplasmin 3. (177 aa) |
| | LOC104653719 | Bromo domain-containing protein. (592 aa) |
| | LOC104672435 | Uncharacterized protein. (180 aa) |
| | ENSRROP00000011815 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (261 aa) |
| | JMJD7 | Jumonji domain containing 7. (316 aa) |
| | ENSRROP00000012193 | Uncharacterized protein. (185 aa) |
| | BRDT | Bromodomain testis associated. (951 aa) |
| | TBL1X | Transducin beta like 1 X-linked. (575 aa) |
| | BRWD1 | Bromodomain and WD repeat domain containing 1. (2288 aa) |
| | ENSRROP00000012616 | Uncharacterized protein. (280 aa) |
| | KDM1B | Lysine demethylase 1B. (822 aa) |
| | KDM7A | Lysine demethylase 7A. (941 aa) |
| | ENSRROP00000013712 | Bromo domain-containing protein. (522 aa) |
| | MTF2 | Metal response element binding transcription factor 2. (593 aa) |
| | UIMC1 | Ubiquitin interaction motif containing 1. (719 aa) |
| | TAF1 | TATA-box binding protein associated factor 1. (1196 aa) |
| | BRD7 | Bromo domain-containing protein. (652 aa) |
| | LOC104656366 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (277 aa) |
| | ING5 | Inhibitor of growth family member 5. (254 aa) |
| | ATAD2B | ATPase family AAA domain containing 2B. (1458 aa) |
| | IPO7 | Importin 7. (1038 aa) |
| | MYSM1 | Myb like, SWIRM and MPN domains 1. (828 aa) |
| | CBX2 | Chromobox 2. (521 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | SAMD7 | Sterile alpha motif domain containing 7. (446 aa) |
| | ASF1B | Anti-silencing function 1B histone chaperone. (199 aa) |
| | ENSRROP00000016702 | Uncharacterized protein. (108 aa) |
| | LOC104659750 | SAP domain-containing protein. (362 aa) |
| | MSL3 | MSL complex subunit 3. (522 aa) |
| | KDM5B | Lysine demethylase 5B. (1580 aa) |
| | LOC104677785 | Uncharacterized protein. (118 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (549 aa) |
| | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor. (1033 aa) |
| | ENSRROP00000017334 | H15 domain-containing protein. (199 aa) |
| | BRD1 | Bromodomain containing 1. (1189 aa) |
| | FAM162A | Family with sequence similarity 162 member A. (155 aa) |
| | ENSRROP00000017493 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (391 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (780 aa) |
| | STPG4 | Sperm-tail PG-rich repeat containing 4. (247 aa) |
| | DAXX | Daxx domain-containing protein. (744 aa) |
| | CTCFL | CCCTC-binding factor like. (697 aa) |
| | TSPYL4 | TSPY like 4; Belongs to the nucleosome assembly protein (NAP) family. (304 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa) |
| | VRK1 | VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa) |
| | INO80 | INO80 complex ATPase subunit. (1556 aa) |
| | PTMA | Uncharacterized protein. (136 aa) |
| | BRWD3 | Bromodomain and WD repeat domain containing 3. (1795 aa) |
| | USP49 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (688 aa) |
| | PRMT7 | Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (701 aa) |
| | ZMYND11 | Zinc finger MYND-type containing 11. (635 aa) |
| | PHF19 | PHD finger protein 19. (599 aa) |
| | CBX7 | Chromobox 7. (251 aa) |
| | YEATS2 | YEATS domain containing 2. (1419 aa) |
| | PHF13 | PHD finger protein 13. (316 aa) |
| | CARM1 | Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (564 aa) |
| | LOC104669136 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (301 aa) |
| | LOC104653593 | Uncharacterized protein. (277 aa) |
| | SFMBT2 | Scm like with four mbt domains 2. (876 aa) |
| | HJURP | Holliday junction recognition protein. (732 aa) |
| | ENSRROP00000020587 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (293 aa) |
| | AIRE | Autoimmune regulator. (547 aa) |
| | SBNO1 | Strawberry notch homolog 1. (1393 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1130 aa) |
| | PRKCB | Non-specific serine/threonine protein kinase. (590 aa) |
| | SIRT1 | Sirtuin 1. (746 aa) |
| | UHRF2 | Ubiquitin like with PHD and ring finger domains 2. (802 aa) |
| | LOC104668601 | SAP domain-containing protein. (320 aa) |
| | BPTF | Bromodomain PHD finger transcription factor. (3031 aa) |
| | PHF6 | PHD finger protein 6. (365 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (950 aa) |
| | KMT2E | Lysine methyltransferase 2E. (1878 aa) |
| | BAZ1B | Bromodomain adjacent to zinc finger domain 1B. (1483 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | ING1 | Inhibitor of growth protein. (406 aa) |
| | CBX3 | Uncharacterized protein. (183 aa) |
| | KMT2D | Lysine methyltransferase 2D. (5538 aa) |
| | SUPT6H | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (506 aa) |
| | ENSRROP00000023500 | Nucleoplasmin domain-containing protein. (214 aa) |
| | ENSRROP00000023796 | Uncharacterized protein. (778 aa) |
| | ENSRROP00000023956 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (373 aa) |
| | SPHK2 | Sphingosine kinase 2. (665 aa) |
| | PWP1 | PWP1 homolog, endonuclein. (501 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1201 aa) |
| | BRD3 | Bromodomain containing 3. (726 aa) |
| | WDR73 | WD repeat domain 73. (372 aa) |
| | L3MBTL2 | L3MBTL histone methyl-lysine binding protein 2. (714 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (740 aa) |
| | ANP32B | Acidic nuclear phosphoprotein 32 family member B. (251 aa) |
| | DPF2 | Double PHD fingers 2. (405 aa) |
| | TRIM24 | Tripartite motif containing 24. (1048 aa) |
| | LOC104674840 | WD_REPEATS_REGION domain-containing protein. (478 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (925 aa) |
| | LOC104657064 | Uncharacterized protein. (213 aa) |
| | CBX8 | Chromobox 8. (387 aa) |
| | WDR38 | WD repeat domain 38. (314 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1378 aa) |
| | BRD9 | Bromodomain containing 9. (550 aa) |
| | ENSRROP00000026439 | WD_REPEATS_REGION domain-containing protein. (363 aa) |
| | NAP1L3 | Nucleosome assembly protein 1 like 3; Belongs to the nucleosome assembly protein (NAP) family. (505 aa) |
| | SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (739 aa) |
| | ENSRROP00000045760 | Uncharacterized protein. (264 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) |
| | DPPA3 | Uncharacterized protein. (152 aa) |
| | UHRF1 | Ubiquitin like with PHD and ring finger domains 1. (859 aa) |
| | APBB1 | Amyloid beta precursor protein binding family B member 1. (746 aa) |
| | BRD4 | Bromodomain containing 4. (1314 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (468 aa) |
| | C17orf64 | Chromosome 17 open reading frame 64. (236 aa) |
| | IPO9 | Importin 9. (1041 aa) |
| | ENSRROP00000044391 | WD_REPEATS_REGION domain-containing protein. (379 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | RBBP5 | RB binding protein 5, histone lysine methyltransferase complex subunit. (548 aa) |
| | ZNHIT1 | Zinc finger HIT-type containing 1. (154 aa) |
| | SGF29 | SAGA complex associated factor 29. (293 aa) |
| | PHIP | Pleckstrin homology domain interacting protein. (1821 aa) |
| | SBNO2 | Strawberry notch homolog 2. (1236 aa) |
| | KMT2C | Lysine methyltransferase 2C. (4916 aa) |
| | PTMS | Parathymosin. (103 aa) |
| | ENSRROP00000042897 | Uncharacterized protein. (165 aa) |
| | FMR1 | Fragile X mental retardation 1. (624 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | TTLL12 | Tubulin tyrosine ligase like 12. (644 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2582 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (818 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa) |
| | ENSRROP00000041906 | YDG domain-containing protein. (711 aa) |
| | NPM2 | Nucleophosmin/nucleoplasmin 2. (214 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa) |
| | PYGO1 | Pygopus family PHD finger 1. (432 aa) |
| | SCMH1 | Scm polycomb group protein homolog 1. (660 aa) |
| | CXXC1 | CXXC finger protein 1. (655 aa) |
| | KDM5A | Lysine demethylase 5A. (1690 aa) |
| | PSME4 | Proteasome activator subunit 4. (1844 aa) |
| | RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) |
| | TBL1XR1 | Transducin beta like 1 X-linked receptor 1. (514 aa) |
| | ENSRROP00000039888 | DEK_C domain-containing protein. (355 aa) |
| | WDR5 | WD repeat domain 5. (342 aa) |
| | JARID2 | Jumonji and AT-rich interaction domain containing 2. (1246 aa) |
| | USP3 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (503 aa) |
| | SCML2 | SAM domain-containing protein. (139 aa) |
| | HAT1 | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa) |
| | RCC1 | Regulator of chromosome condensation 1. (461 aa) |
| | PHC2 | Polyhomeotic homolog 2. (859 aa) |
| | SET | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (308 aa) |
| | DPF1 | Double PHD fingers 1. (406 aa) |
| | ZMYND8 | Zinc finger MYND-type containing 8. (1241 aa) |
| | L3MBTL4 | L3MBTL histone methyl-lysine binding protein 4. (623 aa) |
| | LRWD1 | Leucine rich repeats and WD repeat domain containing 1. (681 aa) |
| | CHD4 | Uncharacterized protein. (1913 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (907 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (486 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa) |
| | SAMD13 | Sterile alpha motif domain containing 13. (120 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | MLLT1 | MLLT1 super elongation complex subunit. (391 aa) |
