42 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RXRA	Retinoid X receptor alpha. (481 aa)
	TAF8	TATA-box binding protein associated factor 8. (311 aa)
	NCOA2	Nuclear receptor coactivator. (1475 aa)
	TAF5	TATA-box binding protein associated factor 5. (800 aa)
	EPAS1	Endothelial PAS domain protein 1. (865 aa)
	S100A10	S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
	NCOA1	Nuclear receptor coactivator. (1441 aa)
	TAF2	TATA-box binding protein associated factor 2. (1251 aa)
	TAF4	TATA-box binding protein associated factor 4. (635 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (511 aa)
	LOC104655794	Transcription initiation factor TFIID subunit 13. (124 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1177 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
	VDR	Vitamin D receptor. (477 aa)
	TFCP2	Transcription factor CP2. (502 aa)
	TBP	TATA-box binding protein. (333 aa)
	ENSRROP00000024732	Uncharacterized protein. (252 aa)
	SUPT6H	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	C5AR1	Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
	LOC104669754	Uncharacterized protein. (124 aa)
	STAT3	Signal transducer and activator of transcription. (802 aa)
	RARA	Retinoic acid receptor alpha. (478 aa)
	ZBTB1	Zinc finger and BTB domain containing 1. (668 aa)
	TAF1	TATA-box binding protein associated factor 1. (1196 aa)
	ENSRROP00000012907	Uncharacterized protein. (116 aa)
	TAF4B	TATA-box binding protein associated factor 4b. (862 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (790 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	HLTF	Helicase like transcription factor. (1008 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	ZIC3	Zic family member 3. (466 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	TAF12	TATA-box binding protein associated factor 12. (213 aa)
	ENSRROP00000006623	EF-hand domain-containing protein; Belongs to the S-100 family. (97 aa)
	TAF3	TATA-box binding protein associated factor 3. (931 aa)
	LOC104674542	Uncharacterized protein. (264 aa)
	HNRNPD	Heterogeneous nuclear ribonucleoprotein D. (355 aa)
	THRA	Thyroid hormone receptor alpha. (590 aa)
	TAF6	TATA-box binding protein associated factor 6. (738 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ATF4	ENSRROP00000009970	ENSRROP00000007388	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Activating transcription factor 4.	0.940
ATF2	CREB1	ENSRROP00000009970	ENSRROP00000022920	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 1.	0.966
ATF2	STAT3	ENSRROP00000009970	ENSRROP00000018412	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Signal transducer and activator of transcription.	0.472
ATF4	ATF2	ENSRROP00000007388	ENSRROP00000009970	Activating transcription factor 4.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.940
ATF4	CREB1	ENSRROP00000007388	ENSRROP00000022920	Activating transcription factor 4.	cAMP responsive element binding protein 1.	0.929
CREB1	ATF2	ENSRROP00000022920	ENSRROP00000009970	cAMP responsive element binding protein 1.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.966
CREB1	ATF4	ENSRROP00000022920	ENSRROP00000007388	cAMP responsive element binding protein 1.	Activating transcription factor 4.	0.929
CREB1	STAT3	ENSRROP00000022920	ENSRROP00000018412	cAMP responsive element binding protein 1.	Signal transducer and activator of transcription.	0.608
CREB1	TAF4	ENSRROP00000022920	ENSRROP00000039901	cAMP responsive element binding protein 1.	TATA-box binding protein associated factor 4.	0.940
CREB1	TAF4B	ENSRROP00000022920	ENSRROP00000011711	cAMP responsive element binding protein 1.	TATA-box binding protein associated factor 4b.	0.840
ENSRROP00000006623	HLTF	ENSRROP00000006623	ENSRROP00000008955	EF-hand domain-containing protein; Belongs to the S-100 family.	Helicase like transcription factor.	0.772
ENSRROP00000012907	SUPT6H	ENSRROP00000012907	ENSRROP00000023263	Uncharacterized protein.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.514
ENSRROP00000024732	LOC104655794	ENSRROP00000024732	ENSRROP00000031537	Uncharacterized protein.	Transcription initiation factor TFIID subunit 13.	0.846
ENSRROP00000024732	LOC104669754	ENSRROP00000024732	ENSRROP00000018605	Uncharacterized protein.	Uncharacterized protein.	0.846
ENSRROP00000024732	MED1	ENSRROP00000024732	ENSRROP00000029917	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.455
ENSRROP00000024732	TAF1	ENSRROP00000024732	ENSRROP00000014310	Uncharacterized protein.	TATA-box binding protein associated factor 1.	0.946
ENSRROP00000024732	TAF10	ENSRROP00000024732	ENSRROP00000041308	Uncharacterized protein.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.963
ENSRROP00000024732	TAF12	ENSRROP00000024732	ENSRROP00000007016	Uncharacterized protein.	TATA-box binding protein associated factor 12.	0.964
ENSRROP00000024732	TAF2	ENSRROP00000024732	ENSRROP00000038218	Uncharacterized protein.	TATA-box binding protein associated factor 2.	0.928
ENSRROP00000024732	TAF3	ENSRROP00000024732	ENSRROP00000005993	Uncharacterized protein.	TATA-box binding protein associated factor 3.	0.909