(45 nodes) Negative regulation of I-kappaB kinase/NF-kappaB signaling network (Rhinopithecus roxellana)

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Known Interactions

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Predicted Interactions

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Your Input:
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (244 aa)
	RIOK3	Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (598 aa)
	NLRP12	NLR family pyrin domain containing 12. (1004 aa)
	PPM1B	Protein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
	LOC104678360	Nuclear receptor domain-containing protein. (231 aa)
	RORA	RAR related orphan receptor A. (555 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	TANK	TRAF family member associated NFKB activator. (457 aa)
	ENSRROP00000036403	PPM-type phosphatase domain-containing protein. (342 aa)
	TNFAIP3	TNF alpha induced protein 3. (790 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (486 aa)
	STAT1	Signal transducer and activator of transcription. (787 aa)
	MAPKBP1	Mitogen-activated protein kinase binding protein 1. (1514 aa)
	LOC104677352	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
	NLRC3	NLR family CARD domain containing 3. (1066 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (601 aa)
	TRIM39	Tripartite motif containing 39. (518 aa)
	TNIP1	TNFAIP3 interacting protein 1. (637 aa)
	TNIP3	TNFAIP3 interacting protein 3. (377 aa)
	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
	OTUD7A	OTU deubiquitinase 7A. (733 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (671 aa)
	NLRX1	NLR family member X1. (972 aa)
	SIRT1	Sirtuin 1. (746 aa)
	ENSRROP00000019405	Hist_deacetyl domain-containing protein. (352 aa)
	ZMYND11	Zinc finger MYND-type containing 11. (635 aa)
	PER1	Period circadian regulator 1. (1292 aa)
	CACTIN	Cactin, spliceosome C complex subunit. (724 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
	CARD19	Caspase recruitment domain family member 19. (183 aa)
	NLRP6	NLR family pyrin domain containing 6. (1041 aa)
	LILRB4	Leukocyte immunoglobulin like receptor B4. (471 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (542 aa)
	TLE1	TLE family member 1, transcriptional corepressor. (770 aa)
	PPM1N	Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (430 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (613 aa)
	RHOH	Ras homolog family member H. (191 aa)
	ASH1L	ASH1 like histone lysine methyltransferase. (2916 aa)
	OTUD7B	OTU deubiquitinase 7B. (843 aa)
	USP10	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa)
	DAB2IP	DAB2 interacting protein. (1189 aa)
	CCDC22	Coiled-coil domain containing 22. (627 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	STAT1	ENSRROP00000016398	ENSRROP00000033613	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.444
ADIPOQ	SIRT1	ENSRROP00000013667	ENSRROP00000021023	Adiponectin, C1Q and collagen domain containing.	Sirtuin 1.	0.565
CASP8	PYCARD	ENSRROP00000013257	ENSRROP00000039913	Caspase 8; Belongs to the peptidase C14A family.	PYD and CARD domain containing.	0.978
CASP8	RIPK1	ENSRROP00000013257	ENSRROP00000022822	Caspase 8; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 1.	0.999
ENSRROP00000019405	LOC104678360	ENSRROP00000019405	ENSRROP00000044141	Hist_deacetyl domain-containing protein.	Nuclear receptor domain-containing protein.	0.713
ENSRROP00000019405	SIRT1	ENSRROP00000019405	ENSRROP00000021023	Hist_deacetyl domain-containing protein.	Sirtuin 1.	0.556
ENSRROP00000019405	STAT1	ENSRROP00000019405	ENSRROP00000033613	Hist_deacetyl domain-containing protein.	Signal transducer and activator of transcription.	0.568
ENSRROP00000019405	TLE1	ENSRROP00000019405	ENSRROP00000009654	Hist_deacetyl domain-containing protein.	TLE family member 1, transcriptional corepressor.	0.560
ENSRROP00000036403	PPM1B	ENSRROP00000036403	ENSRROP00000044442	PPM-type phosphatase domain-containing protein.	Protein phosphatase, Mg2+/Mn2+ dependent 1B.	0.586
ENSRROP00000036403	PPM1N	ENSRROP00000036403	ENSRROP00000009627	PPM-type phosphatase domain-containing protein.	Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative).	0.539
HDAC1	LOC104678360	ENSRROP00000015472	ENSRROP00000044141	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor domain-containing protein.	0.713
HDAC1	SIRT1	ENSRROP00000015472	ENSRROP00000021023	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Sirtuin 1.	0.556
HDAC1	STAT1	ENSRROP00000015472	ENSRROP00000033613	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.568
HDAC1	TLE1	ENSRROP00000015472	ENSRROP00000009654	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE family member 1, transcriptional corepressor.	0.560
LOC104677352	LOC104678360	ENSRROP00000029153	ENSRROP00000044141	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor domain-containing protein.	0.713
LOC104677352	SIRT1	ENSRROP00000029153	ENSRROP00000021023	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Sirtuin 1.	0.556
LOC104677352	STAT1	ENSRROP00000029153	ENSRROP00000033613	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.568
LOC104677352	TLE1	ENSRROP00000029153	ENSRROP00000009654	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE family member 1, transcriptional corepressor.	0.560
LOC104678360	ENSRROP00000019405	ENSRROP00000044141	ENSRROP00000019405	Nuclear receptor domain-containing protein.	Hist_deacetyl domain-containing protein.	0.713
LOC104678360	HDAC1	ENSRROP00000044141	ENSRROP00000015472	Nuclear receptor domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.713