STRINGSTRING
PER2 PER2 FBXL3 FBXL3 PPP1CA PPP1CA CRTC1 CRTC1 USP2 USP2 OPN5 OPN5 PDE6B PDE6B PER3 PER3 PPP1CC PPP1CC ENSRROP00000030430 ENSRROP00000030430 PPP1CB PPP1CB TP53 TP53 FBXL17 FBXL17 FBXL21P FBXL21P CRY1 CRY1 FBXL8 FBXL8 NR2F6 NR2F6 FBXL22 FBXL22 RBM4B RBM4B RBM4 RBM4 PER1 PER1 FBXL6 FBXL6 CRY2 CRY2 FBXL12 FBXL12 MTA1 MTA1 PML PML ID2 ID2 ATOH7 ATOH7 BHLHE40 BHLHE40
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PER2Period circadian regulator 2. (1253 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
CRTC1CREB regulated transcription coactivator 1. (608 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (635 aa)
OPN5Opsin 5; Belongs to the G-protein coupled receptor 1 family. (354 aa)
PDE6BPhosphodiesterase. (855 aa)
PER3Period circadian regulator 3. (1178 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ENSRROP00000030430Uncharacterized protein. (297 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (373 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
FBXL17F-box and leucine rich repeat protein 17. (471 aa)
FBXL21PF-box domain-containing protein. (434 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
FBXL8F-box domain-containing protein. (374 aa)
NR2F6Nuclear receptor subfamily 2 group F member 6. (386 aa)
FBXL22F-box and leucine rich repeat protein 22. (231 aa)
RBM4BRNA binding motif protein 4B. (359 aa)
RBM4Uncharacterized protein. (193 aa)
PER1Period circadian regulator 1. (1292 aa)
FBXL6F-box and leucine rich repeat protein 6. (534 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
FBXL12F-box and leucine rich repeat protein 12. (326 aa)
MTA1Metastasis associated 1. (697 aa)
PMLPromyelocytic leukemia. (882 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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