STRINGSTRING
PLA2G4D PLA2G4D ENSRROP00000045789 ENSRROP00000045789 ILVBL ILVBL ABHD12 ABHD12 NAPEPLD NAPEPLD SESN2 SESN2 PLCG2 PLCG2 LIPH LIPH GCDH GCDH ZPBP2 ZPBP2 HEXA HEXA PLB1 PLB1 ASAH1 ASAH1 ASAH2B ASAH2B CEL CEL CROT CROT ABCD2 ABCD2 ACAD11 ACAD11 PNPLA7 PNPLA7 SIRT2 SIRT2 ADTRP ADTRP SLC27A2 SLC27A2 FAAH FAAH BCO1 BCO1 MGLL MGLL PLD2 PLD2 ECHS1 ECHS1 HEXB HEXB CPT1A CPT1A CYP26A1 CYP26A1 GDPD1 GDPD1 ACOX2 ACOX2 PLA2G4C PLA2G4C ABHD16A ABHD16A LPL LPL TMEM130 TMEM130 ACAD10 ACAD10 PHYH PHYH ETFB ETFB EHHADH EHHADH ACOX3 ACOX3 SLC27A4 SLC27A4 APOA5 APOA5 MCAT MCAT DECR1 DECR1 ECHDC2 ECHDC2 ENSRROP00000034847 ENSRROP00000034847 ENSRROP00000034679 ENSRROP00000034679 CYP26B1 CYP26B1 ABCD3 ABCD3 LPIN1 LPIN1 PNPLA3 PNPLA3 SMPD1 SMPD1 DDHD2 DDHD2 PLBD1 PLBD1 GDE1 GDE1 AUH AUH GBA GBA CRABP1 CRABP1 ABHD12B ABHD12B CYP2W1 CYP2W1 GDPD3 GDPD3 HAO1 HAO1 LOC104666481 LOC104666481 ABHD2 ABHD2 ACADVL ACADVL PLA2G4B PLA2G4B SMPD2 SMPD2 INPP5F INPP5F ABHD6 ABHD6 GLA GLA ABCD1 ABCD1 NUDT8 NUDT8 LCT LCT PLA2G4E PLA2G4E PEX7 PEX7 ABCD4 ABCD4 AKR1C3 AKR1C3 PLCG1 PLCG1 ETFA ETFA PLA2G15 PLA2G15 PLA2G7 PLA2G7 NEU2 NEU2 DECR2 DECR2 SMPDL3B SMPDL3B PLCB1 PLCB1 HADH HADH PLA2G6 PLA2G6 ACAT1 ACAT1 LIPC LIPC ACER3 ACER3 APOB APOB PNPLA5 PNPLA5 ABHD3 ABHD3 ALDH1L2 ALDH1L2 ACAA2 ACAA2 ETFDH ETFDH LPIN2 LPIN2 ECI1 ECI1 GBA2 GBA2 ECI2 ECI2 LEP LEP PLBD2 PLBD2 SMIM24 SMIM24 ENSRROP00000017642 ENSRROP00000017642 HADHA HADHA GALC GALC LIPG LIPG ACADM ACADM HSD17B10 HSD17B10 CPS1 CPS1 PNPLA2 PNPLA2 HACL1 HACL1 ENSRROP00000016332 ENSRROP00000016332 PNPLA1 PNPLA1 SRD5A3 SRD5A3 ACOXL ACOXL SPHK1 SPHK1 LIPE LIPE PEX13 PEX13 AMACR AMACR GM2A GM2A PCCB PCCB ADIPOQ ADIPOQ PCCA PCCA PLA2G5 PLA2G5 PLA2G4A PLA2G4A ACAT2 ACAT2 LYPLA2 LYPLA2 LIPI LIPI SMPD3 SMPD3 SLC25A17 SLC25A17 GBA3 GBA3 ENSRROP00000011530 ENSRROP00000011530 CPT1B CPT1B ACER2 ACER2 ACAA1 ACAA1 ASAH2 ASAH2 ENSRROP00000010719 ENSRROP00000010719 PNPLA4 PNPLA4 CPT2 CPT2 AOAH AOAH CPT1C CPT1C ENSRROP00000010327 ENSRROP00000010327 AIG1 AIG1 SGPL1 SGPL1 ENSRROP00000010119 ENSRROP00000010119 PPARD PPARD NEU3 NEU3 GPCPD1 GPCPD1 CYP26C1 CYP26C1 ABHD1 ABHD1 BCO2 BCO2 APOA2 APOA2 ECHDC1 ECHDC1 CRAT CRAT PEX5 PEX5 ACADS ACADS MGST2 MGST2 CYP1B1 CYP1B1 ACOT8 ACOT8 HSD17B4 HSD17B4 MTLN MTLN PNPLA8 PNPLA8 SCP2 SCP2 LOC104678924 LOC104678924 MT3 MT3 HADHB HADHB ENPP2 ENPP2 ACOX1 ACOX1 NEU1 NEU1 ACER1 ACER1 MCEE MCEE BDH2 BDH2 ANGPTL3 ANGPTL3 ENSRROP00000004181 ENSRROP00000004181 PEX2 PEX2 NUDT19 NUDT19 PLD1 PLD1 PLPP6 PLPP6 NEU4 NEU4 PLD1-2 PLD1-2 ACADL ACADL PCK2 PCK2 NAGA NAGA ENPP7 ENPP7 NUDT7 NUDT7 PLA2G4F PLA2G4F DAGLA DAGLA GPIHBP1 GPIHBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4DPhospholipase A2. (816 aa)
ENSRROP00000045789Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (357 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (632 aa)
ABHD12Abhydrolase domain containing 12. (404 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (393 aa)
SESN2Sestrin 2. (518 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
LIPHLipase H. (455 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
ZPBP2Zona pellucida binding protein 2. (337 aa)
HEXABeta-hexosaminidase. (559 aa)
PLB1Phospholipase B1. (1462 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (411 aa)
ASAH2BN-acylsphingosine amidohydrolase 2B. (112 aa)
CELCarboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. (709 aa)
CROTCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (781 aa)
PNPLA7Patatin like phospholipase domain containing 7. (1342 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (370 aa)
ADTRPAndrogen dependent TFPI regulating protein. (248 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
FAAHFatty acid amide hydrolase. (579 aa)
BCO1Beta-carotene oxygenase 1. (547 aa)
MGLLMonoglyceride lipase. (339 aa)
PLD2Phospholipase. (933 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
HEXBBeta-hexosaminidase. (556 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
GDPD1Glycerophosphodiester phosphodiesterase domain containing 1. (314 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
ABHD16AAbhydrolase domain containing 16A. (311 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
TMEM130Transmembrane protein 130. (423 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1095 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (338 aa)
ETFBElectron transfer flavoprotein subunit beta. (345 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
SLC27A4Solute carrier family 27 member 4. (651 aa)
APOA5Apolipoprotein A5. (366 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (390 aa)
DECR12,4-dienoyl-CoA reductase 1. (339 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
ENSRROP00000034847Uncharacterized protein. (133 aa)
ENSRROP00000034679Uncharacterized protein. (81 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
ABCD3ATP binding cassette subfamily D member 3. (659 aa)
LPIN1Lipin 1. (945 aa)
PNPLA3Patatin like phospholipase domain containing 3. (481 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (644 aa)
DDHD2DDHD domain containing 2. (711 aa)
PLBD1Phospholipase B-like; Putative phospholipase. (553 aa)
GDE1Glycerophosphodiester phosphodiesterase 1. (331 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (341 aa)
GBAGlucosylceramidase. (533 aa)
CRABP1Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
ABHD12BAbhydrolase domain containing 12B. (362 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (490 aa)
GDPD3Glycerophosphodiester phosphodiesterase domain containing 3. (318 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
LOC104666481Uncharacterized protein. (413 aa)
ABHD2Abhydrolase domain containing 2. (463 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (655 aa)
PLA2G4BPhospholipase A2. (798 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (451 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1132 aa)
ABHD6Abhydrolase domain containing 6. (336 aa)
GLAAlpha-galactosidase. (429 aa)
ABCD1ATP binding cassette subfamily D member 1. (745 aa)
NUDT8Nudix hydrolase 8. (236 aa)
LCTLactase. (1928 aa)
PLA2G4EPhospholipase A2. (869 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
ABCD4ATP binding cassette subfamily D member 4. (606 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (323 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
PLA2G15Phospholipase A2 group XV. (412 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (439 aa)
NEU2Neuraminidase 2. (380 aa)
DECR22,4-dienoyl-CoA reductase 2. (293 aa)
SMPDL3BSphingomyelin phosphodiesterase acid like 3B. (339 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa)
HADHHydroxyacyl-CoA dehydrogenase. (342 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
LIPCLipase C, hepatic type. (499 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
APOBApolipoprotein B. (4555 aa)
PNPLA5Patatin like phospholipase domain containing 5. (429 aa)
ABHD3Abhydrolase domain containing 3. (409 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (619 aa)
LPIN2Lipin 2. (933 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (302 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (928 aa)
ECI2Enoyl-CoA delta isomerase 2. (391 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
PLBD2Phospholipase B-like; Putative phospholipase. (568 aa)
SMIM24Small integral membrane protein 24. (129 aa)
ENSRROP00000017642Glucosylceramidase. (376 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (765 aa)
GALCGalactosylceramidase. (685 aa)
LIPGLipase G, endothelial type. (500 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (454 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
CPS1Carbamoyl-phosphate synthase 1. (1514 aa)
PNPLA2Patatin like phospholipase domain containing 2. (501 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
ENSRROP00000016332Uncharacterized protein. (722 aa)
PNPLA1Patatin like phospholipase domain containing 1. (533 aa)
SRD5A3Steroid 5 alpha-reductase 3. (318 aa)
ACOXLAcyl-CoA_dh_M domain-containing protein. (249 aa)
SPHK1Sphingosine kinase 1. (472 aa)
LIPELipase E, hormone sensitive type. (1054 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
AMACRAlpha-methylacyl-CoA racemase. (382 aa)
GM2AGM2 ganglioside activator. (190 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (570 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (728 aa)
PLA2G5Phospholipase A(2). (138 aa)
PLA2G4APhospholipase A2. (749 aa)
ACAT2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
LYPLA2Lysophospholipase 2. (231 aa)
LIPILipase I. (480 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
SLC25A17Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
GBA3Glucosylceramidase beta 3 (gene/pseudogene); Belongs to the glycosyl hydrolase 1 family. (469 aa)
ENSRROP00000011530Uncharacterized protein. (148 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
ASAH2Neutral ceramidase. (666 aa)
ENSRROP00000010719VOC domain-containing protein. (171 aa)
PNPLA4Patatin like phospholipase domain containing 4. (253 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (659 aa)
AOAHAcyloxyacyl hydrolase. (687 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
ENSRROP00000010327Uncharacterized protein. (57 aa)
AIG1Androgen induced 1. (245 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
ENSRROP00000010119Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
NEU3Neuraminidase 3. (461 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (672 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
ABHD1Abhydrolase domain containing 1. (406 aa)
BCO2Beta-carotene oxygenase 2. (579 aa)
APOA2Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. (132 aa)
ECHDC1Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (307 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (627 aa)
PEX5Peroxisomal biogenesis factor 5. (660 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
MGST2Microsomal glutathione S-transferase 2. (147 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
ACOT8Acyl-CoA thioesterase 8. (328 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (759 aa)
MTLNMitoregulin. (119 aa)
PNPLA8Patatin like phospholipase domain containing 8. (782 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
LOC104678924Aldo_ket_red domain-containing protein. (356 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (940 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
NEU1Neuraminidase 1. (416 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
MCEEVOC domain-containing protein. (176 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (245 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
ENSRROP00000004181Uncharacterized protein. (80 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
NUDT19Nudix hydrolase 19. (375 aa)
PLD1Phospholipase D1. (586 aa)
PLPP6Phospholipid phosphatase 6. (296 aa)
NEU4Neuraminidase 4. (497 aa)
PLD1-2Uncharacterized protein. (57 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
NAGAAlpha-galactosidase. (411 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (450 aa)
NUDT7Nudix hydrolase 7. (238 aa)
PLA2G4FPhospholipase A2. (849 aa)
DAGLADiacylglycerol lipase alpha. (1043 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (184 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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