STRINGSTRING
IFI35 IFI35 LYN LYN PAK2 PAK2 ENSRROP00000006168 ENSRROP00000006168 TRIM56 TRIM56 NOD2 NOD2 COLEC10 COLEC10 ENSRROP00000005346 ENSRROP00000005346 KIR3DL3 KIR3DL3 CXorf21 CXorf21 FFAR2 FFAR2 ENSRROP00000004076 ENSRROP00000004076 HEXIM1 HEXIM1 ENSRROP00000002798 ENSRROP00000002798 ENSRROP00000002311 ENSRROP00000002311 LOC104669987 LOC104669987 ZCCHC3 ZCCHC3 TOMM70 TOMM70 ENSRROP00000001202 ENSRROP00000001202 FCN2 FCN2 IL21 IL21 ENSRROP00000000939 ENSRROP00000000939 CREBBP CREBBP MBL2 MBL2 KLRD1 KLRD1 WNT5A WNT5A XRCC5 XRCC5 ENSRROP00000015769 ENSRROP00000015769 RNF185 RNF185 IFI16 IFI16 LOC104676775 LOC104676775 COCH COCH NECTIN2 NECTIN2 PQBP1 PQBP1 MNDA MNDA TLR4 TLR4 MMP12 MMP12 FCN3 FCN3 FYN FYN CD160 CD160 AIM2 AIM2 NLRC4 NLRC4 IRF3 IRF3 SRC SRC CLEC6A CLEC6A SYK SYK NCR3 NCR3 ENSRROP00000020473 ENSRROP00000020473 PYHIN1 PYHIN1 SH2D1A SH2D1A LOC104675682 LOC104675682 MASP1 MASP1 IKBKE IKBKE CADM1 CADM1 EREG EREG PSPC1 PSPC1 IKBKB IKBKB ENSRROP00000025349 ENSRROP00000025349 HPX HPX TRIM41 TRIM41 LOC104676771 LOC104676771 TRIM5 TRIM5 POLR3D POLR3D USP27X USP27X CARD9 CARD9 ENSRROP00000027580 ENSRROP00000027580 ENSRROP00000027696 ENSRROP00000027696 LSM14A LSM14A EP300 EP300 PLSCR1 PLSCR1 ADAM8 ADAM8 ENSRROP00000029157 ENSRROP00000029157 ZBP1 ZBP1 KIR2DL4 KIR2DL4 MED1 MED1 SLAMF6 SLAMF6 MATR3 MATR3 LILRA1 LILRA1 POLR3F POLR3F POLR3C POLR3C LAMP1 LAMP1 POLR3B POLR3B LOC104660903 LOC104660903 SFPQ SFPQ HSP90AA1 HSP90AA1 FADD FADD LOC104668623 LOC104668623 KLRK1 KLRK1 POLR3G POLR3G CGAS CGAS AKIRIN2 AKIRIN2 NLRC5 NLRC5 CD226 CD226 HLA-E HLA-E IL12A IL12A ENSRROP00000039750 ENSRROP00000039750 ENSRROP00000039767 ENSRROP00000039767 NONO NONO PYCARD PYCARD TBK1 TBK1 ENSRROP00000040276 ENSRROP00000040276 SLC15A4 SLC15A4 LOC104667511 LOC104667511 PARP9 PARP9 TXK TXK RBM14 RBM14 CLNK CLNK SIN3A SIN3A PVR PVR PLCG2 PLCG2 PAK1 PAK1 PRKDC PRKDC TIRAP TIRAP STING1 STING1 RASGRP1 RASGRP1 RIOK3 RIOK3 STAT5B STAT5B TYROBP TYROBP ENSRROP00000012041 ENSRROP00000012041 CRTAM CRTAM TRIM62 TRIM62 PLA2G5 PLA2G5 VAV1 VAV1 LOC104682584 LOC104682584 XRCC6 XRCC6 TLR8 TLR8 LAG3 LAG3 COLEC11 COLEC11 MASP2 MASP2 ENSRROP00000010534 ENSRROP00000010534 IRF7 IRF7 NMI NMI ZNFX1 ZNFX1 HAVCR2 HAVCR2 LOC104675385 LOC104675385 LOC104675178 LOC104675178 MAVS MAVS UBE2K UBE2K LOC104675310 LOC104675310 CASP6 CASP6 LBP LBP SH2D1B SH2D1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFI35Interferon induced protein 35. (292 aa)
LYNTyrosine-protein kinase. (491 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSRROP00000006168IGc1 domain-containing protein; Belongs to the MHC class I family. (345 aa)
TRIM56Tripartite motif containing 56. (755 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
COLEC10Collectin subfamily member 10. (277 aa)
ENSRROP00000005346Ig-like domain-containing protein; Belongs to the MHC class I family. (305 aa)
KIR3DL3Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (428 aa)
CXorf21Chromosome X open reading frame 21. (301 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
ENSRROP00000004076Uncharacterized protein. (101 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
ENSRROP00000002798Ig-like domain-containing protein; Belongs to the MHC class I family. (255 aa)
ENSRROP00000002311Ku domain-containing protein. (539 aa)
LOC104669987MHC_I-like_Ag-recog domain-containing protein. (146 aa)
ZCCHC3Zinc finger CCHC-type containing 3. (402 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
ENSRROP00000001202RRM domain-containing protein. (172 aa)
FCN2Ficolin 2. (313 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ENSRROP00000000939Ig-like domain-containing protein; Belongs to the MHC class I family. (364 aa)
CREBBPCREB binding protein. (2442 aa)
MBL2Mannose binding lectin 2. (255 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
ENSRROP00000015769Uncharacterized protein. (279 aa)
RNF185Ring finger protein 185. (192 aa)
IFI16Interferon gamma inducible protein 16. (729 aa)
LOC104676775Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
COCHCochlin. (580 aa)
NECTIN2Nectin cell adhesion molecule 2. (538 aa)
PQBP1Polyglutamine binding protein 1. (265 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
MMP12Matrix metallopeptidase 12. (470 aa)
FCN3Ficolin 3. (320 aa)
FYNTyrosine-protein kinase. (537 aa)
CD160CD160 molecule. (232 aa)
AIM2Absent in melanoma 2. (343 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (426 aa)
SRCTyrosine-protein kinase. (540 aa)
CLEC6AC-type lectin domain containing 6A. (209 aa)
SYKTyrosine-protein kinase. (635 aa)
NCR3Natural cytotoxicity triggering receptor 3. (189 aa)
ENSRROP00000020473FFD domain-containing protein. (348 aa)
PYHIN1Pyrin and HIN domain family member 1. (492 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
LOC104675682HATPase_c domain-containing protein. (671 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (739 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
CADM1Cell adhesion molecule 1. (475 aa)
EREGEpiregulin. (163 aa)
PSPC1Paraspeckle component 1. (523 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
ENSRROP00000025349Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
HPXHemopexin. (422 aa)
TRIM41Tripartite motif containing 41. (631 aa)
LOC104676771Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (369 aa)
TRIM5Uncharacterized protein. (495 aa)
POLR3DRNA polymerase III subunit D. (417 aa)
USP27XUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
ENSRROP00000027580Uncharacterized protein. (220 aa)
ENSRROP00000027696Uncharacterized protein. (222 aa)
LSM14AUncharacterized protein. (468 aa)
EP300E1A binding protein p300. (2413 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (325 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
ENSRROP00000029157Uncharacterized protein. (457 aa)
ZBP1Z-DNA binding protein 1. (429 aa)
KIR2DL4Uncharacterized protein. (237 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
SLAMF6SLAM family member 6. (331 aa)
MATR3Uncharacterized protein. (888 aa)
LILRA1Uncharacterized protein. (492 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
LAMP1Lysosomal associated membrane protein 1. (412 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa)
LOC104660903IRF-3 domain-containing protein. (342 aa)
SFPQSplicing factor proline and glutamine rich. (585 aa)
HSP90AA1HATPase_c domain-containing protein. (657 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
LOC104668623C-type lectin domain-containing protein. (246 aa)
KLRK1Killer cell lectin like receptor K1. (216 aa)
POLR3GDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
CGASCyclic GMP-AMP synthase. (523 aa)
AKIRIN2Akirin 2. (212 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
CD226CD226 molecule. (336 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
ENSRROP00000039750MHC_I-like_Ag-recog domain-containing protein. (247 aa)
ENSRROP00000039767Ig-like domain-containing protein. (237 aa)
NONONon-POU domain containing octamer binding. (471 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TBK1TANK binding kinase 1. (729 aa)
ENSRROP00000040276MHC_I-like_Ag-recog domain-containing protein. (233 aa)
SLC15A4Solute carrier family 15 member 4. (527 aa)
LOC104667511Uncharacterized protein. (840 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (818 aa)
TXKTyrosine-protein kinase. (527 aa)
RBM14RNA binding motif protein 14. (669 aa)
CLNKCytokine dependent hematopoietic cell linker. (428 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
PVRPVR cell adhesion molecule. (413 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4159 aa)
TIRAPTIR domain containing adaptor protein. (219 aa)
STING1Transmembrane protein 173. (379 aa)
RASGRP1RAS guanyl releasing protein 1. (841 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (598 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (123 aa)
ENSRROP00000012041Uncharacterized protein. (204 aa)
CRTAMCytotoxic and regulatory T cell molecule. (393 aa)
TRIM62Tripartite motif containing 62. (470 aa)
PLA2G5Phospholipase A(2). (138 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
LOC104682584HATPase_c domain-containing protein. (674 aa)
XRCC6X-ray repair cross complementing 6. (617 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1041 aa)
LAG3Lymphocyte activating 3. (525 aa)
COLEC11Collectin subfamily member 11. (304 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
ENSRROP00000010534U1-type domain-containing protein. (511 aa)
IRF7Interferon regulatory factor 7. (503 aa)
NMIN-myc and STAT interactor. (307 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (293 aa)
LOC104675385AIG1-type G domain-containing protein. (323 aa)
LOC104675178MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (224 aa)
MAVSCARD_2 domain-containing protein. (545 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
LOC104675310Uncharacterized protein. (484 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (293 aa)
LBPLipopolysaccharide binding protein. (484 aa)
SH2D1BSH2 domain containing 1B. (132 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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