STRINGSTRING
ARSA ARSA PENK PENK RGS19 RGS19 KCNC2 KCNC2 VCAM1 VCAM1 EHMT2 EHMT2 GLRA2 GLRA2 CRHBP CRHBP PRKCE PRKCE CSF3 CSF3 CASP8 CASP8 GRIN3A GRIN3A SPINK1 SPINK1 POLB POLB ADIPOQ ADIPOQ AVP AVP UNC79 UNC79 CRHR1 CRHR1 CYBB CYBB CLDN7 CLDN7 PPARA PPARA FGF19 FGF19 CYP7A1 CYP7A1 TUFM TUFM GATA3 GATA3 ITPR2 ITPR2 DMAP1 DMAP1 ABCB11 ABCB11 PSMD14 PSMD14 HMGCS2 HMGCS2 GRIN1 GRIN1 CLDN5 CLDN5 BAD BAD TP53INP1 TP53INP1 CHRNB2 CHRNB2 SLC23A2 SLC23A2 IGF1R IGF1R TYMS TYMS FYN FYN G6PD G6PD DNMT3A DNMT3A RARA RARA HDAC2 HDAC2 FGFR2 FGFR2 NLRP3 NLRP3 GRIN2B GRIN2B GABBR1 GABBR1 NPPC NPPC ENSRROP00000043954 ENSRROP00000043954 DBH DBH GRIN2A GRIN2A SOD1 SOD1 TBXA2R TBXA2R DRD2 DRD2 TH TH RGS7 RGS7 ENSRROP00000040164 ENSRROP00000040164 GNRH1 GNRH1 PTK2B PTK2B NR0B2 NR0B2 CPT1A CPT1A SLC10A1 SLC10A1 OPRM1 OPRM1 ADCY7 ADCY7 CLDN1 CLDN1 MAOB MAOB RPS6KB1 RPS6KB1 GOT2 GOT2 EPS8 EPS8 S100A8 S100A8 BIRC2 BIRC2 OGG1 OGG1 CBL CBL ADCYAP1R1 ADCYAP1R1 SREBF1 SREBF1 CD14 CD14 TJP1 TJP1 DRD4 DRD4 ENSRROP00000026864 ENSRROP00000026864 ABAT ABAT RGS2 RGS2 CA3 CA3 BAK1 BAK1 EIF4G1 EIF4G1 ST6GAL1 ST6GAL1 TACR1 TACR1 GLRA1 GLRA1 ADH7 ADH7 CLDN3 CLDN3 SLC2A4 SLC2A4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARSAArylsulfatase A. (507 aa)
PENKProenkephalin. (267 aa)
RGS19Regulator of G protein signaling 19. (217 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1237 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CSF3Colony stimulating factor 3. (204 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
UNC79Unc-79 homolog, NALCN channel complex subunit. (2657 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
PPARAPeroxisome proliferator activated receptor alpha. (398 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (454 aa)
GATA3GATA binding protein 3. (444 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (467 aa)
ABCB11ATP binding cassette subfamily B member 11. (1321 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (924 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (279 aa)
BADBCL2 associated agonist of cell death. (167 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (504 aa)
SLC23A2Solute carrier family 23 member 2. (650 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
TYMSThymidylate synthetase. (313 aa)
FYNTyrosine-protein kinase. (537 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (545 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
RARARetinoic acid receptor alpha. (478 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
FGFR2Fibroblast growth factor receptor. (837 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (962 aa)
NPPCNatriuretic peptide C. (126 aa)
ENSRROP00000043954Tr-type G domain-containing protein. (370 aa)
DBHDopamine beta-hydroxylase. (572 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
TBXA2RThromboxane A2 receptor. (384 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
THTyrosine hydroxylase. (532 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
ENSRROP00000040164Aminotran_1_2 domain-containing protein. (363 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (105 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
SLC10A1Solute carrier family 10 member 1. (349 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
MAOBAmine oxidase. (520 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
GOT2Aspartate aminotransferase. (430 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (837 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
OGG18-oxoguanine DNA glycosylase. (404 aa)
CBLCbl proto-oncogene. (906 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
CD14CD14 molecule. (384 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1756 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (326 aa)
ENSRROP00000026864Aspartate aminotransferase. (389 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (509 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
CA3Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (290 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1604 aa)
ST6GAL1ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
ADH7Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (394 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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