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EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa) | ||||
NAGLU | N-acetyl-alpha-glucosaminidase. (743 aa) | ||||
NCOA2 | Nuclear receptor coactivator. (1475 aa) | ||||
ID2 | Inhibitor of DNA binding 2. (134 aa) | ||||
CIART | Circadian associated repressor of transcription. (385 aa) | ||||
NMS | Neuromedin S. (153 aa) | ||||
NCOR1 | Nuclear receptor corepressor 1. (2440 aa) | ||||
USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (635 aa) | ||||
MC3R | Melanocortin 3 receptor. (323 aa) | ||||
MTA1 | Metastasis associated 1. (697 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |