STRINGSTRING
ADIPOQ ADIPOQ MMP11 MMP11 GPS2 GPS2 ID4 ID4 FOXO1 FOXO1 ZFP36L2 ZFP36L2 GATA2 GATA2 TGFB1 TGFB1 SIRT2 SIRT2 CCN4 CCN4 RORA RORA WNT10B WNT10B ZFPM1 ZFPM1 TRIB3 TRIB3 LRP3 LRP3 E2F1 E2F1 TRPV4 TRPV4 WNT3A WNT3A TGFB1I1 TGFB1I1 TRIB2 TRIB2 AXIN1 AXIN1 TRIO TRIO C1QL4 C1QL4 ARNTL ARNTL GPER1 GPER1 GATA3 GATA3 ENSRROP00000022699 ENSRROP00000022699 ENPP1 ENPP1 SIRT1 SIRT1 YAP1 YAP1 FLCN FLCN RUNX1T1 RUNX1T1 INSIG1 INSIG1 ZADH2 ZADH2 ZFPM2 ZFPM2 WNT5A WNT5A ASXL1 ASXL1 JDP2 JDP2 CCDC85B CCDC85B WNT1 WNT1 BBS12 BBS12 LOC104664133 LOC104664133 TLCD3B TLCD3B SMAD3 SMAD3 DDIT3 DDIT3 WWTR1 WWTR1 SORT1 SORT1 FERMT2 FERMT2 ANKRD26 ANKRD26 ENSRROP00000013240 ENSRROP00000013240 JAG1 JAG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
MMP11Matrix metallopeptidase 11. (488 aa)
GPS2G protein pathway suppressor 2. (327 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (153 aa)
FOXO1Forkhead box O1. (585 aa)
ZFP36L2ZFP36 ring finger protein like 2. (497 aa)
GATA2GATA binding protein 2. (480 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (370 aa)
CCN4Cellular communication network factor 4. (367 aa)
RORARAR related orphan receptor A. (555 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ZFPM1Uncharacterized protein. (143 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
LRP3LDL receptor related protein 3. (770 aa)
E2F1E2F transcription factor 1. (485 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (456 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
AXIN1Axin 1. (867 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3073 aa)
C1QL4Complement C1q like 4. (238 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (341 aa)
GATA3GATA binding protein 3. (444 aa)
ENSRROP00000022699Uncharacterized protein. (356 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (917 aa)
SIRT1Sirtuin 1. (746 aa)
YAP1Yes associated protein 1. (508 aa)
FLCNFolliculin. (579 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (615 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (283 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (363 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ASXL1ASXL transcriptional regulator 1. (1536 aa)
JDP2Jun dimerization protein 2. (175 aa)
CCDC85BCoiled-coil domain containing 85B. (202 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
BBS12Bardet-Biedl syndrome 12. (710 aa)
LOC104664133ANK_REP_REGION domain-containing protein. (283 aa)
TLCD3BTLC domain containing 3B. (274 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
SORT1Sortilin. (699 aa)
FERMT2Fermitin family member 2. (695 aa)
ANKRD26Ankyrin repeat domain 26. (1700 aa)
ENSRROP00000013240ANK_REP_REGION domain-containing protein. (97 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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