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| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (378 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | GSTM5 | Uncharacterized protein; Belongs to the GST superfamily. (218 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (609 aa) |
| | UGDH | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa) |
| | ENSRROP00000000616 | CS domain-containing protein. (136 aa) |
| | HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8. (261 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa) |
| | MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (333 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase. (199 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | CARNS1 | Carnosine synthase 1. (950 aa) |
| | MIF | Uncharacterized protein. (115 aa) |
| | THNSL1 | Threonine synthase like 1. (743 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (698 aa) |
| | ENSRROP00000003271 | SHMT domain-containing protein. (414 aa) |
| | ARMC7 | Armadillo repeat containing 7. (198 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | DHFR2 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. (175 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (418 aa) |
| | ENSRROP00000004269 | Pyr_redox_2 domain-containing protein. (378 aa) |
| | OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (842 aa) |
| | ASS1 | Uncharacterized protein. (412 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (565 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | SDS | Serine dehydratase. (331 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa) |
| | ENSRROP00000005654 | Uncharacterized protein. (103 aa) |
| | SRR | Serine racemase. (339 aa) |
| | LOC104670790 | DHFR domain-containing protein. (181 aa) |
| | OSBPL3 | Oxysterol-binding protein; Belongs to the OSBP family. (887 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (400 aa) |
| | LDHC | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | ENSRROP00000007048 | Uncharacterized protein. (129 aa) |
| | PNPLA8 | Patatin like phospholipase domain containing 8. (782 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | GSTP1 | Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa) |
| | ENSRROP00000007257 | Uncharacterized protein. (66 aa) |
| | PTGES | Prostaglandin E synthase. (152 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa) |
| | ENSRROP00000007515 | Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (351 aa) |
| | ENSRROP00000007609 | DJ-1_PfpI domain-containing protein. (153 aa) |
| | ACOT8 | Acyl-CoA thioesterase 8. (328 aa) |
| | BHMT | Betaine--homocysteine S-methyltransferase. (470 aa) |
| | EDN1 | Endothelin 1. (211 aa) |
| | ENSRROP00000007768 | Uncharacterized protein. (371 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (147 aa) |
| | PRXL2B | Peroxiredoxin like 2B. (227 aa) |
| | ENSRROP00000008157 | Uncharacterized protein. (413 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (646 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (279 aa) |
| | LOC104665044 | Uncharacterized protein. (455 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | ASNS | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (859 aa) |
| | ABHD1 | Abhydrolase domain containing 1. (406 aa) |
| | ENSRROP00000009222 | DHFR domain-containing protein. (152 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | OSBPL2 | Oxysterol-binding protein; Belongs to the OSBP family. (480 aa) |
| | ASAH2 | Neutral ceramidase. (666 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | OLAH | Oleoyl-ACP hydrolase. (315 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | LOC104671265 | Uncharacterized protein. (225 aa) |
| | LIPI | Lipase I. (480 aa) |
| | THNSL2 | Threonine synthase like 2. (499 aa) |
| | PER2 | Period circadian regulator 2. (1253 aa) |
| | ACSM5 | Acyl-CoA synthetase medium chain family member 5. (580 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (980 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (162 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | CYP3A4 | Cytochrome P450 family 3 subfamily A member 4. (503 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | ENSRROP00000013258 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (170 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (363 aa) |
| | ENSRROP00000013527 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (354 aa) |
| | GATM | Glycine amidinotransferase. (423 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (298 aa) |
| | PCCB | Propionyl-CoA carboxylase subunit beta. (570 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (369 aa) |
| | LOC104662872 | Uncharacterized protein. (115 aa) |
| | AMACR | Alpha-methylacyl-CoA racemase. (382 aa) |
| | NOXRED1 | NADP dependent oxidoreductase domain containing 1. (359 aa) |
| | GAMT | Guanidinoacetate N-methyltransferase. (251 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (517 aa) |
| | CRABP2 | Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | ENSRROP00000015323 | DHFR domain-containing protein. (145 aa) |
| | EDN2 | Endothelin 2. (178 aa) |
| | OAT | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | MTHFD2L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (310 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1514 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | LIPG | Lipase G, endothelial type. (500 aa) |
| | GLUD2 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (537 aa) |
| | UPB1 | Beta-ureidopropionase 1. (403 aa) |
| | ASNSD1 | Glutamine amidotransferase type-2 domain-containing protein. (641 aa) |
| | ENSRROP00000017874 | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (348 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | SUGCT | Uncharacterized protein. (470 aa) |
| | ENSRROP00000019132 | Uncharacterized protein. (340 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | ACSM1 | Acyl-CoA synthetase medium chain family member 1. (475 aa) |
| | PTGES3 | CS domain-containing protein. (164 aa) |
| | ENSRROP00000019989 | Uncharacterized protein. (124 aa) |
| | LTC4S | Leukotriene C4 synthase. (150 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (274 aa) |
| | ENSRROP00000020953 | Aminotran_5 domain-containing protein. (342 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (494 aa) |
| | LOC104679638 | Glutamate decarboxylase 2. (305 aa) |
| | GATD1 | Glutamine amidotransferase like class 1 domain containing 1. (213 aa) |
| | RGN | Regucalcin. (299 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (415 aa) |
| | ABHD3 | Abhydrolase domain containing 3. (409 aa) |
| | FADS1 | Fatty acid desaturase 1. (444 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1321 aa) |
| | LIPC | Lipase C, hepatic type. (499 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | GLS2 | Glutaminase 2. (602 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | SDSL | Serine dehydratase like. (329 aa) |
| | DECR2 | 2,4-dienoyl-CoA reductase 2. (293 aa) |
| | CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (705 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (346 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa) |
| | AGXT2 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | PSPH | Phosphoserine phosphatase. (225 aa) |
| | LOC104679892 | BRCT domain-containing protein. (96 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (533 aa) |
| | PRG3 | Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (961 aa) |
| | DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | LOC104673929 | Uncharacterized protein. (252 aa) |
| | LOC104663113 | Uncharacterized protein. (392 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (323 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (701 aa) |
| | PTGDS | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa) |
| | LOC104677212 | Lipoxygenase domain-containing protein. (345 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (925 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2225 aa) |
| | LOC104656408 | Bile_Hydr_Trans domain-containing protein. (214 aa) |
| | ENSRROP00000026108 | Uncharacterized protein. (358 aa) |
| | ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (509 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa) |
| | ENSRROP00000026864 | Aspartate aminotransferase. (389 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | ENSRROP00000027231 | THF_DHG_CYH_C domain-containing protein. (885 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | LOC104660785 | Uncharacterized protein. (463 aa) |
| | FADS3 | Fatty acid desaturase 3. (445 aa) |
| | SLC1A3 | Amino acid transporter. (542 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa) |
| | ASL | Lyase_1 domain-containing protein. (135 aa) |
| | ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa) |
| | ENSRROP00000028174 | KH domain-containing protein. (282 aa) |
| | GGT5 | Uncharacterized protein. (322 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (477 aa) |
| | ENSRROP00000028768 | Uncharacterized protein. (78 aa) |
| | DAGLB | Diacylglycerol lipase beta. (705 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (370 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (736 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa) |
| | ENSRROP00000029268 | Aminotran_5 domain-containing protein. (351 aa) |
| | ALOX5AP | Arachidonate 5-lipoxygenase activating protein. (217 aa) |
| | PLP1 | Proteolipid protein 1. (279 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (697 aa) |
| | ENSRROP00000029496 | Aminotran_5 domain-containing protein. (134 aa) |
| | LOC104660851 | Uncharacterized protein. (288 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein. (326 aa) |
| | GLUD1 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (562 aa) |
| | BHMT2 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa) |
| | LTA4H | Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (611 aa) |
| | ENSRROP00000030966 | Uncharacterized protein. (103 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (166 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa) |
| | GGT7 | Gamma-glutamyltransferase 7. (662 aa) |
| | LOC104665273 | Uncharacterized protein; Belongs to the peptidase C14A family. (406 aa) |
| | BCAT2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (407 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase type B. (676 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (463 aa) |
| | GGT1 | Uncharacterized protein. (430 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa) |
| | LOC104674799 | Uncharacterized protein. (97 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | ALDH8A1 | Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | SCD | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | PAH | Phenylalanine hydroxylase. (452 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (560 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2442 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1836 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | GOT2 | Aspartate aminotransferase. (430 aa) |
| | TECR | Trans-2,3-enoyl-CoA reductase. (308 aa) |
| | QKI | KH domain-containing protein. (341 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | WDR37 | WD repeat domain 37. (495 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (659 aa) |
| | RBP1 | Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa) |
| | ENSRROP00000034731 | Uncharacterized protein. (284 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase. (390 aa) |
| | ENSRROP00000035340 | Uncharacterized protein. (162 aa) |
| | PTGES2 | Prostaglandin E synthase 2. (377 aa) |
| | OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa) |
| | LOC104682074 | Uncharacterized protein. (577 aa) |
| | GGT6 | Gamma-glutamyltransferase 6. (498 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase. (322 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | CTH | Cystathionine gamma-lyase. (405 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | ENSRROP00000036753 | ELFV_dehydrog domain-containing protein. (150 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa) |
| | GLS | Glutaminase. (669 aa) |
| | NANP | N-acetylneuraminic acid phosphatase. (248 aa) |
| | LOC104673354 | Uncharacterized protein. (617 aa) |
| | BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (403 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | TMED8 | Transmembrane p24 trafficking protein family member 8. (326 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | MGLL | Monoglyceride lipase. (339 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (576 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | MECR | Mitochondrial trans-2-enoyl-CoA reductase. (373 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | ENSRROP00000039494 | Aldo_ket_red domain-containing protein. (334 aa) |
| | ENSRROP00000039682 | Uncharacterized protein. (347 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (688 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (620 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1403 aa) |
| | GSTM4 | Glutathione S-transferase mu 4; Belongs to the GST superfamily. (218 aa) |
| | ENSRROP00000040164 | Aminotran_1_2 domain-containing protein. (363 aa) |
| | FASN | Fatty acid synthase. (2504 aa) |
| | NAGS | N-acetylglutamate synthase. (534 aa) |
| | LOC104654299 | Cytochrome b5 heme-binding domain-containing protein. (484 aa) |
| | ENSRROP00000040954 | Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (347 aa) |
| | LOC104680069 | Fer4_20 domain-containing protein. (173 aa) |
| | SLC27A5 | Solute carrier family 27 member 5. (690 aa) |
| | LGSN | Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (507 aa) |
| | TMEM196 | Transmembrane protein 196. (182 aa) |
| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (805 aa) |
| | ASAH2B | N-acylsphingosine amidohydrolase 2B. (112 aa) |
| | GAD1 | Glutamate decarboxylase 1. (594 aa) |
| | UROS | Uroporphyrinogen III synthase. (265 aa) |
| | PHGDH | Phosphoglycerate dehydrogenase. (548 aa) |
| | LOC104662101 | Uncharacterized protein; Belongs to the cytochrome P450 family. (519 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (402 aa) |
| | PYCR2 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) |
| | ACSM3 | Acyl-CoA synthetase medium chain family member 3. (586 aa) |
| | GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (233 aa) |
| | APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa) |
| | AKR1A1 | Aldo_ket_red domain-containing protein. (325 aa) |
| | LOC104675180 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (180 aa) |
| | PLA2G1B | Phospholipase A2 group IB. (180 aa) |
| | LIPH | Lipase H. (455 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (984 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1148 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (506 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (950 aa) |
| | LOC104678116 | Glutathione S-transferase. (243 aa) |
| | ILVBL | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. (632 aa) |
| | LOC104672650 | Uncharacterized protein. (152 aa) |
