STRINGSTRING
FYCO1 FYCO1 TRAK2 TRAK2 KIF13A KIF13A BICDL2 BICDL2 KIF1A KIF1A HTT HTT LOC104675287 LOC104675287 BICDL1 BICDL1 KIF3B KIF3B FBXW11 FBXW11 PRKCZ PRKCZ BLOC1S5 BLOC1S5 BLOC1S2 BLOC1S2 RAB1A RAB1A RASGRP1 RASGRP1 KIFAP3 KIFAP3 SNAPIN SNAPIN HAP1 HAP1 BLOC1S6 BLOC1S6 AP3S1 AP3S1 KIF5B KIF5B ENSRROP00000004412 ENSRROP00000004412 BLOC1S4 BLOC1S4 AP3B2 AP3B2 AP3M1 AP3M1 ENSRROP00000012946 ENSRROP00000012946 AP3D1 AP3D1 DTNBP1 DTNBP1 ENSRROP00000015361 ENSRROP00000015361 NDE1 NDE1 AP3M2 AP3M2 DYNC1H1 DYNC1H1 TRAK1 TRAK1 AP3B1 AP3B1 CLN3 CLN3 DYNC1I1 DYNC1I1 KIF1C KIF1C TRIM46 TRIM46 ENSRROP00000028830 ENSRROP00000028830
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FYCO1FYVE and coiled-coil domain containing 1. (1498 aa)
TRAK2Trafficking kinesin protein 2. (914 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1839 aa)
BICDL2BICD family like cargo adaptor 2. (508 aa)
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1786 aa)
HTTHuntingtin. (3100 aa)
LOC104675287Uncharacterized protein. (213 aa)
BICDL1BICD family like cargo adaptor 1. (622 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (187 aa)
BLOC1S2Biogenesis of lysosomal organelles complex 1 subunit 2. (142 aa)
RAB1AUncharacterized protein. (188 aa)
RASGRP1RAS guanyl releasing protein 1. (841 aa)
KIFAP3Kinesin associated protein 3. (792 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
HAP1Huntingtin associated protein 1. (644 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
AP3S1Adaptor related protein complex 3 subunit sigma 1. (193 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
ENSRROP00000004412Uncharacterized protein. (427 aa)
BLOC1S4Uncharacterized protein. (217 aa)
AP3B2AP-3 complex subunit beta. (1101 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (468 aa)
ENSRROP00000012946Uncharacterized protein. (213 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1211 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
ENSRROP00000015361Uncharacterized protein. (190 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4636 aa)
TRAK1Trafficking kinesin protein 1. (953 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
CLN3Battenin. (438 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
KIF1CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (608 aa)
TRIM46Tripartite motif containing 46. (559 aa)
ENSRROP00000028830Uncharacterized protein. (136 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.