STRINGSTRING
WNT7A WNT7A RIPPLY2 RIPPLY2 MATN1 MATN1 SOX6 SOX6 BARX2 BARX2 ENSRROP00000000108 ENSRROP00000000108 ENSRROP00000000669 ENSRROP00000000669 PHOSPHO2 PHOSPHO2 ATG9A ATG9A CSRNP1 CSRNP1 TGFB3 TGFB3 FOXC2 FOXC2 MEF2D MEF2D P2RX7 P2RX7 GRHL2 GRHL2 RDH10 RDH10 BMP7 BMP7 LOC104659307 LOC104659307 THRA THRA ANKRD11 ANKRD11 WWOX WWOX TGFBR2 TGFBR2 ALX1 ALX1 SIX4 SIX4 IFT140 IFT140 NOG NOG IFITM5 IFITM5 COL13A1 COL13A1 HYAL2 HYAL2 COL2A1 COL2A1 DSCAML1 DSCAML1 NEUROG1 NEUROG1 PSEN1 PSEN1 ENSRROP00000005643 ENSRROP00000005643 SMAD3 SMAD3 HOXD8 HOXD8 MGP MGP ZFAND5 ZFAND5 TRIP11 TRIP11 HOXD4 HOXD4 CDX1 CDX1 NIPBL NIPBL HOXA5 HOXA5 HOXB6 HOXB6 FGF4 FGF4 IMPAD1 IMPAD1 TULP3 TULP3 ANXA6 ANXA6 LOC104659433 LOC104659433 ANKRD12 ANKRD12 ZMPSTE24 ZMPSTE24 OSR1 OSR1 LTF LTF ATF2 ATF2 LOC104680386 LOC104680386 SGPL1 SGPL1 SETD2 SETD2 PPARGC1B PPARGC1B BMPR2 BMPR2 MEGF8 MEGF8 TBX4 TBX4 WDR48 WDR48 TBXT TBXT THBS3 THBS3 HOXA11 HOXA11 TMEM107 TMEM107 MTHFD1L MTHFD1L INPPL1 INPPL1 HOXB5 HOXB5 FREM1 FREM1 ALX4 ALX4 DLG1 DLG1 AXIN2 AXIN2 HYAL1 HYAL1 SKI SKI LOC104666521 LOC104666521 EXT1 EXT1 HOXC4 HOXC4 MMP14 MMP14 TSKU TSKU HOXD9 HOXD9 NKX3-2 NKX3-2 BMP6 BMP6 DLX5 DLX5 DLX2 DLX2 FGFR2 FGFR2 INSIG1 INSIG1 WNT9B WNT9B RARA RARA SHOX2 SHOX2 HHIP HHIP DCANP1 DCANP1 HAS2 HAS2 TFAP2A TFAP2A RAB33B RAB33B PLEKHA1 PLEKHA1 PKD1 PKD1 ACP5 ACP5 MMP16 MMP16 BMPR1B BMPR1B PRRX1 PRRX1 COL3A1 COL3A1 GLG1 GLG1 NAB1 NAB1 SERPINH1 SERPINH1 SIX1 SIX1 RARG RARG GLI3 GLI3 HOXB7 HOXB7 PRKRA PRKRA SMAD2 SMAD2 MED12 MED12 HOXC9 HOXC9 COL11A1 COL11A1 IFT80 IFT80 RAB23 RAB23 TGFBR1 TGFBR1 HOXD10 HOXD10 ENSRROP00000025010 ENSRROP00000025010 PHOSPHO1 PHOSPHO1 LRP5 LRP5 FGFR1 FGFR1 MAPK14 MAPK14 GSC GSC SOX9 SOX9 PEX7 PEX7 FLVCR1 FLVCR1 DHRS3 DHRS3 HOXC8 HOXC8 ACVR2B ACVR2B ALPL ALPL RUNX2 RUNX2 RYK RYK SLC39A1 SLC39A1 HOXB3 HOXB3 FUZ FUZ HOXA3 HOXA3 TRPV4 TRPV4 NODAL NODAL BMP1 BMP1 MMP2 MMP2 COL27A1 COL27A1 IRX5 IRX5 PAX1 PAX1 ACAN ACAN HOXA4 HOXA4 CTNNB1 CTNNB1 DSPP DSPP FGF8 FGF8 RFLNB RFLNB TBX15 TBX15 TCF15 TCF15 NLE1 NLE1 SCUBE2 SCUBE2 CITED2 CITED2 OSR2 OSR2 PAPPA2 PAPPA2 OTOR OTOR ARID5B ARID5B FGF6 FGF6 WDR19 WDR19 RARB RARB FGR FGR WDR60 WDR60 MSX1 MSX1 ALX3 ALX3 MYF5 MYF5 CYP26B1 CYP26B1 NAB2 NAB2 ENSRROP00000034722 ENSRROP00000034722 CHSY1 CHSY1 MEF2C MEF2C EYA1 EYA1 MDFI MDFI TIPARP TIPARP BMP4 BMP4 SFRP1 SFRP1 ZEB1 ZEB1 ENSRROP00000037464 ENSRROP00000037464 EIF4A3 EIF4A3 MMP13 MMP13 LOC104663799 LOC104663799 STC1 STC1 FGFR3 FGFR3 HOXB1 HOXB1 HOXA1 HOXA1 PAX5 PAX5 NDST1 NDST1 CER1 CER1 PCGF2 PCGF2 ENSRROP00000039864 ENSRROP00000039864 SOX5 SOX5 SIX2 SIX2 TGFB1 TGFB1 HOXA2 HOXA2 LTBP3 LTBP3 LOC104655538 LOC104655538 ATG9B ATG9B IHH IHH ACTN3 ACTN3 COMP COMP COL11A2 COL11A2 FGF18 FGF18 EXT2 EXT2 RFLNA RFLNA HOXD3 HOXD3 COL1A1 COL1A1 HOXB9 HOXB9 SATB2 SATB2 HOXB2 HOXB2 FMN1 FMN1 WNT10B WNT10B FBN2 FBN2 NPPC NPPC CCN2 CCN2 SFRP4 SFRP4 SPEF2 SPEF2 HOXB8 HOXB8 ENSRROP00000044837 ENSRROP00000044837 HOXC11 HOXC11 SP5 SP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
MATN1Matrilin 1. (496 aa)
SOX6SRY-box transcription factor 6. (461 aa)
BARX2BARX homeobox 2. (279 aa)
ENSRROP00000000108Uncharacterized protein. (166 aa)
ENSRROP00000000669Fork-head domain-containing protein. (435 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (852 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (593 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FOXC2Forkhead box C2. (501 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
GRHL2Grainyhead like transcription factor 2. (633 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
LOC104659307TB domain-containing protein. (166 aa)
THRAThyroid hormone receptor alpha. (590 aa)
ANKRD11Ankyrin repeat domain 11. (2692 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ALX1ALX homeobox 1. (326 aa)
SIX4SIX homeobox 4. (780 aa)
IFT140Intraflagellar transport 140. (1466 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
COL13A1Collagen type XIII alpha 1 chain. (717 aa)
HYAL2Hyaluronidase. (473 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
DSCAML1DS cell adhesion molecule like 1. (2113 aa)
NEUROG1Neurogenin 1. (238 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
ENSRROP00000005643Uncharacterized protein. (495 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
HOXD8Homeobox domain-containing protein. (106 aa)
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (128 aa)
ZFAND5Zinc finger AN1-type containing 5. (213 aa)
TRIP11Thyroid hormone receptor interactor 11. (1980 aa)
HOXD4Homeobox D4. (255 aa)
CDX1Caudal type homeobox 1. (154 aa)
NIPBLNipped-B protein. (2804 aa)
HOXA5Homeobox A5. (270 aa)
HOXB6Homeobox B6. (224 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
IMPAD1Inositol monophosphatase domain containing 1. (373 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (482 aa)
ANXA6Annexin. (673 aa)
LOC104659433Homeobox domain-containing protein. (289 aa)
ANKRD12Ankyrin repeat domain 12. (2059 aa)
ZMPSTE24Zinc metallopeptidase STE24. (515 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
LTFLactotransferrin; Belongs to the transferrin family. (732 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
LOC104680386Uncharacterized protein. (503 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
PPARGC1BPPARG coactivator 1 beta. (1024 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1002 aa)
MEGF8Multiple EGF like domains 8. (2834 aa)
TBX4T-box transcription factor 4. (584 aa)
WDR48WD repeat domain 48. (700 aa)
TBXTT-box transcription factor T. (435 aa)
THBS3Thrombospondin 3. (956 aa)
HOXA11Homeobox A11. (313 aa)
TMEM107Transmembrane protein 107. (140 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (980 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1302 aa)
HOXB5Homeobox B5. (269 aa)
FREM1FRAS1 related extracellular matrix 1. (2178 aa)
ALX4ALX homeobox 4. (409 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
AXIN2Axin 2. (843 aa)
HYAL1Hyaluronidase. (435 aa)
SKISKI proto-oncogene. (770 aa)
LOC104666521FH2 domain-containing protein. (704 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
HOXC4Homeobox C4. (264 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
TSKUTsukushi, small leucine rich proteoglycan. (489 aa)
HOXD9Homeobox D9. (348 aa)
NKX3-2NK3 homeobox 2. (333 aa)
BMP6Bone morphogenetic protein 6. (439 aa)
DLX5Distal-less homeobox 5. (289 aa)
DLX2Homeobox domain-containing protein. (328 aa)
FGFR2Fibroblast growth factor receptor. (837 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (283 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
RARARetinoic acid receptor alpha. (478 aa)
SHOX2Short stature homeobox 2. (355 aa)
HHIPHedgehog interacting protein. (700 aa)
DCANP1Dendritic cell associated nuclear protein. (208 aa)
HAS2Hyaluronan synthase 2. (460 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4297 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PRRX1Paired related homeobox 1. (245 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
GLG1Golgi glycoprotein 1. (1193 aa)
NAB1NGFI-A binding protein 1. (487 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
SIX1SIX homeobox 1. (284 aa)
RARGRetinoic acid receptor gamma. (456 aa)
GLI3GLI family zinc finger 3. (1580 aa)
HOXB7Homeobox B7. (217 aa)
PRKRAProtein activator of interferon induced protein kinase EIF2AK2. (313 aa)
SMAD2Mothers against decapentaplegic homolog. (392 aa)
MED12Med12-PQL domain-containing protein. (323 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
IFT80Intraflagellar transport 80. (777 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
HOXD10Homeobox D10. (340 aa)
ENSRROP00000025010HMG box domain-containing protein. (196 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
FGFR1Fibroblast growth factor receptor. (872 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GSCGoosecoid homeobox. (259 aa)
SOX9SRY-box transcription factor 9. (509 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (287 aa)
HOXC8Homeobox C8. (242 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
ALPLAlkaline phosphatase. (524 aa)
RUNX2RUNX family transcription factor 2. (541 aa)
RYKReceptor like tyrosine kinase. (623 aa)
SLC39A1Solute carrier family 39 member 1. (325 aa)
HOXB3Homeobox B3. (428 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
HOXA3Homeobox A3. (443 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
NODALNodal growth differentiation factor. (347 aa)
BMP1Metalloendopeptidase. (986 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1830 aa)
IRX5Iroquois homeobox 5. (483 aa)
PAX1Paired box 1. (457 aa)
ACANAggrecan. (2188 aa)
HOXA4Homeobox domain-containing protein. (123 aa)
CTNNB1Catenin beta 1. (781 aa)
DSPPUncharacterized protein. (1263 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
RFLNBRefilin B. (144 aa)
TBX15T-box transcription factor 15. (635 aa)
TCF15Transcription factor 15. (164 aa)
NLE1Notchless homolog 1. (485 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (953 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
OSR2Odd-skipped related transciption factor 2. (423 aa)
PAPPA2Pappalysin 2. (1791 aa)
OTOROtoraplin. (128 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WDR19WD repeat domain 19. (1342 aa)
RARBRetinoic acid receptor beta. (448 aa)
FGRTyrosine-protein kinase. (529 aa)
WDR60WD repeat domain 60. (1067 aa)
MSX1Msh homeobox 1. (261 aa)
ALX3ALX homeobox 3. (343 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
NAB2NGFI-A binding protein 2. (525 aa)
ENSRROP00000034722Uncharacterized protein. (107 aa)
CHSY1Hexosyltransferase. (777 aa)
MEF2CMyocyte enhancer factor 2C. (466 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
MDFIMyoD family inhibitor. (246 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
ENSRROP00000037464Uncharacterized protein. (301 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
MMP13Matrix metallopeptidase 13. (503 aa)
LOC104663799Uncharacterized protein. (246 aa)
STC1Stanniocalcin 1. (247 aa)
FGFR3Fibroblast growth factor receptor. (803 aa)
HOXB1Homeobox B1. (304 aa)
HOXA1Homeobox A1. (335 aa)
PAX5Paired box 5. (391 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
ENSRROP00000039864Homeobox domain-containing protein. (142 aa)
SOX5SRY-box transcription factor 5. (750 aa)
SIX2SIX homeobox 2. (290 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
HOXA2Homeobox A2. (374 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1069 aa)
LOC104655538Fork-head domain-containing protein. (464 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (959 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
COL11A2Collagen type XI alpha 2 chain. (1738 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (769 aa)
RFLNARefilin A. (216 aa)
HOXD3Homeobox D3. (430 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
SATB2DNA-binding protein SATB. (733 aa)
HOXB2Homeobox B2. (356 aa)
FMN1Uncharacterized protein. (659 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
FBN2Fibrillin 2. (2912 aa)
NPPCNatriuretic peptide C. (126 aa)
CCN2Cellular communication network factor 2. (387 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
SPEF2Sperm flagellar 2. (2151 aa)
HOXB8Homeobox B8. (278 aa)
ENSRROP00000044837Uncharacterized protein. (457 aa)
HOXC11Homeobox C11. (304 aa)
SP5Sp5 transcription factor. (376 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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