STRINGSTRING
ATOH1 ATOH1 TGFB3 TGFB3 WNT1 WNT1 PJVK PJVK NEUROD1 NEUROD1 CHD7 CHD7 PHOX2B PHOX2B ATP8A2 ATP8A2 TBX2 TBX2 SIX4 SIX4 CEP290 CEP290 SLITRK6 SLITRK6 C1QTNF5 C1QTNF5 FGF10 FGF10 NTN1 NTN1 COL2A1 COL2A1 HEY2 HEY2 NEUROG1 NEUROG1 OTOP1 OTOP1 CCM2 CCM2 AHI1 AHI1 TRIOBP TRIOBP TRIP11 TRIP11 FOXG1 FOXG1 CXCL14 CXCL14 REST REST WHRN WHRN STRC STRC LOC104680792 LOC104680792 TSHR TSHR BCR BCR CYTL1 CYTL1 ALDH1A3 ALDH1A3 ENSRROP00000010437 ENSRROP00000010437 LGR5 LGR5 BMP2 BMP2 FGF20 FGF20 KCNK3 KCNK3 GRXCR1 GRXCR1 ENSRROP00000011759 ENSRROP00000011759 DLL1 DLL1 SLC44A4 SLC44A4 TCAP TCAP CTHRC1 CTHRC1 JAG1 JAG1 GRHL3 GRHL3 SCRIB SCRIB GABRA5 GABRA5 ZIC1 ZIC1 SLC26A5 SLC26A5 BMPER BMPER PCDH15 PCDH15 CHRNA9 CHRNA9 ADGRV1 ADGRV1 PTPN11 PTPN11 USH1G USH1G WNT5A WNT5A SHH SHH PDGFA PDGFA TSKU TSKU HESX1 HESX1 PROX1 PROX1 DLX5 DLX5 SPRY2 SPRY2 CDH23 CDH23 MYO7A MYO7A HPN HPN FGFR2 FGFR2 INSIG1 INSIG1 ENSRROP00000017624 ENSRROP00000017624 HPCAL1 HPCAL1 HOXA13 HOXA13 PLPPR4 PLPPR4 DCANP1 DCANP1 FZD6 FZD6 TFAP2A TFAP2A DVL2 DVL2 ESRRB ESRRB MPV17 MPV17 FGF9 FGF9 DLX6 DLX6 TBX18 TBX18 PRRX1 PRRX1 SLC17A8 SLC17A8 ENSRROP00000021422 ENSRROP00000021422 PVALB PVALB OTOL1 OTOL1 SIX1 SIX1 LOC104657085 LOC104657085 EYA4 EYA4 LIN7A LIN7A GLI3 GLI3 GBX2 GBX2 GATA3 GATA3 GABRB2 GABRB2 COL11A1 COL11A1 LRIG3 LRIG3 SEC24B SEC24B EPHB2 EPHB2 CCNA2 CCNA2 FZD2 FZD2 ANP32B ANP32B PAX2 PAX2 CLRN1 CLRN1 SOX9 SOX9 CDKN1B CDKN1B KCNQ4 KCNQ4 KCNK2 KCNK2 WNT3A WNT3A ENSRROP00000028188 ENSRROP00000028188 LHFPL5 LHFPL5 GSDME GSDME EPHA4 EPHA4 OTX1 OTX1 MAPKAPK2 MAPKAPK2 TBX3 TBX3 FREM2 FREM2 HMX2 HMX2 CECR2 CECR2 C1QB C1QB FGF8 FGF8 SOBP SOBP TPRN TPRN ATP8B3 ATP8B3 PLS1 PLS1 JAG2 JAG2 HPCA HPCA FOXI1 FOXI1 LOC104665158 LOC104665158 HMX3 HMX3 DCHS1 DCHS1 LRRC1 LRRC1 ENSRROP00000032705 ENSRROP00000032705 ATP6V1B1 ATP6V1B1 TGFB2 TGFB2 PTPRQ PTPRQ ADAM10 ADAM10 ROR1 ROR1 MCOLN3 MCOLN3 POU4F3 POU4F3 LHX3 LHX3 STOX1 STOX1 IFT20 IFT20 CLRN2 CLRN2 EYA1 EYA1 ENSRROP00000036200 ENSRROP00000036200 SLC4A7 SLC4A7 IFT27 IFT27 BMP4 BMP4 PDZD7 PDZD7 ZEB1 ZEB1 PDGFRB PDGFRB TMC1 TMC1 LRIG1 LRIG1 ENSRROP00000037464 ENSRROP00000037464 NOX3 NOX3 MYO3A MYO3A MCM2 MCM2 MYO3B MYO3B MKS1 MKS1 ATG5 ATG5 FZD3 FZD3 HOXA1 HOXA1 KCNQ1 KCNQ1 PTK7 PTK7 GATA2 GATA2 RPGRIP1L RPGRIP1L TGFB1 TGFB1 CHRNA10 CHRNA10 LOC104664865 LOC104664865 BLOC1S5 BLOC1S5 USH1C USH1C NOTCH1 NOTCH1 MYO6 MYO6 GRXCR2 GRXCR2 IFT88 IFT88 TMIE TMIE TTC8 TTC8 ENSRROP00000042123 ENSRROP00000042123 SOD1 SOD1 ATG4B ATG4B SDC4 SDC4 ITGA8 ITGA8 NAGLU NAGLU MYO15B MYO15B DUOX2 DUOX2 LRP10 LRP10 MYO15A MYO15A WDPCP WDPCP FRZB FRZB ATP8B1 ATP8B1 TTC39C TTC39C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATOH1Atonal bHLH transcription factor 1. (354 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PJVKPejvakin. (352 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
PHOX2BPaired like homeobox 2B. (259 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1184 aa)
TBX2T-box transcription factor 2. (712 aa)
SIX4SIX homeobox 4. (780 aa)
CEP290Centrosomal protein 290. (2480 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NTN1Netrin 1. (604 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (309 aa)
NEUROG1Neurogenin 1. (238 aa)
OTOP1Otopetrin 1. (610 aa)
CCM2CCM2 scaffold protein. (466 aa)
AHI1Abelson helper integration site 1. (1196 aa)
TRIOBPTRIO and F-actin binding protein. (2225 aa)
TRIP11Thyroid hormone receptor interactor 11. (1980 aa)
FOXG1Uncharacterized protein. (151 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
RESTRE1 silencing transcription factor. (1096 aa)
WHRNWhirlin. (907 aa)
STRCStereocilin. (1733 aa)
LOC104680792Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (473 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
BCRBCR activator of RhoGEF and GTPase. (1064 aa)
CYTL1Cytokine like 1. (136 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
ENSRROP00000010437Uncharacterized protein. (235 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
BMP2Bone morphogenetic protein 2. (470 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
KCNK3Potassium two pore domain channel subfamily K member 3. (271 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (296 aa)
ENSRROP00000011759Uncharacterized protein. (274 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (748 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (737 aa)
TCAPTitin-cap. (167 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
GRHL3Grainyhead like transcription factor 3. (608 aa)
SCRIBScribble planar cell polarity protein. (1660 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ZIC1Zic family member 1. (447 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (744 aa)
BMPERBMP binding endothelial regulator. (685 aa)
PCDH15Protocadherin related 15. (1929 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6169 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
USH1GUSH1 protein network component sans. (461 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SHHHH_signal domain-containing protein. (141 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (169 aa)
TSKUTsukushi, small leucine rich proteoglycan. (489 aa)
HESX1HESX homeobox 1. (185 aa)
PROX1Prospero homeobox 1. (737 aa)
DLX5Distal-less homeobox 5. (289 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
CDH23Cadherin related 23. (3367 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2215 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
FGFR2Fibroblast growth factor receptor. (837 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (283 aa)
ENSRROP00000017624PKD_channel domain-containing protein. (476 aa)
HPCAL1Hippocalcin like 1. (193 aa)
HOXA13Homeobox A13. (219 aa)
PLPPR4Phospholipid phosphatase related 4. (763 aa)
DCANP1Dendritic cell associated nuclear protein. (208 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
ESRRBEstrogen related receptor beta. (500 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
DLX6Distal-less homeobox 6. (276 aa)
TBX18T-box transcription factor 18. (607 aa)
PRRX1Paired related homeobox 1. (245 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
ENSRROP00000021422Uncharacterized protein. (534 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (111 aa)
OTOL1Otolin 1. (470 aa)
SIX1SIX homeobox 1. (284 aa)
LOC104657085Uncharacterized protein. (3665 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (639 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
GLI3GLI family zinc finger 3. (1580 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
GATA3GATA binding protein 3. (444 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1119 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (690 aa)
EPHB2EPH receptor B2. (1058 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (251 aa)
PAX2Paired box 2. (417 aa)
CLRN1Clarin 1. (245 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (428 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ENSRROP00000028188Protein kinase domain-containing protein. (247 aa)
LHFPL5LHFPL tetraspan subfamily member 5. (219 aa)
GSDMEGasdermin E. (496 aa)
EPHA4EPH receptor A4. (986 aa)
OTX1Orthodenticle homeobox 1. (288 aa)
MAPKAPK2MAPK activated protein kinase 2. (322 aa)
TBX3T-box transcription factor 3. (743 aa)
FREM2FRAS1 related extracellular matrix 2. (3170 aa)
HMX2H6 family homeobox 2. (273 aa)
CECR2CECR2 histone acetyl-lysine reader. (1419 aa)
C1QBComplement C1q B chain. (253 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SOBPSine oculis binding protein homolog. (709 aa)
TPRNTaperin. (507 aa)
ATP8B3Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1307 aa)
PLS1Plastin 1. (629 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1051 aa)
HPCAHippocalcin. (193 aa)
FOXI1Forkhead box I1. (378 aa)
LOC104665158Uncharacterized protein. (282 aa)
HMX3H6 family homeobox 3. (318 aa)
DCHS1Dachsous cadherin-related 1. (3295 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
ENSRROP00000032705Uncharacterized protein. (89 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2332 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (925 aa)
MCOLN3PKD_channel domain-containing protein. (553 aa)
POU4F3POU domain protein. (338 aa)
LHX3LIM homeobox 3. (407 aa)
STOX1Storkhead box 1. (886 aa)
IFT20Intraflagellar transport 20. (158 aa)
CLRN2Clarin 2. (232 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
ENSRROP00000036200Uncharacterized protein. (491 aa)
SLC4A7Anion exchange protein. (1259 aa)
IFT27Intraflagellar transport 27. (186 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
PDZD7PDZ domain containing 7. (1004 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
TMC1Transmembrane channel-like protein. (761 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1089 aa)
ENSRROP00000037464Uncharacterized protein. (301 aa)
NOX3NADPH oxidase 3. (570 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1163 aa)
MCM2DNA helicase; Belongs to the MCM family. (907 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1341 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
HOXA1Homeobox A1. (335 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (549 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
GATA2GATA binding protein 2. (480 aa)
RPGRIP1LRPGRIP1 like. (1314 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
LOC104664865Uncharacterized protein. (1545 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (187 aa)
USH1CUSH1 protein network component harmonin. (899 aa)
NOTCH1Notch receptor 1. (2560 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (248 aa)
IFT88Intraflagellar transport 88. (824 aa)
TMIETransmembrane inner ear. (154 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
ENSRROP00000042123Uncharacterized protein. (251 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (394 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
MYO15BMyosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2974 aa)
DUOX2Dual oxidase 2. (1548 aa)
LRP10LDL receptor related protein 10. (715 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3408 aa)
WDPCPWD repeat containing planar cell polarity effector. (608 aa)
FRZBFrizzled related protein. (325 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1246 aa)
TTC39CTetratricopeptide repeat domain 39C. (594 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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