STRINGSTRING
IL23A IL23A FYN FYN CLECL1 CLECL1 ZMIZ1 ZMIZ1 LEP LEP YES1 YES1 RARA RARA ENSRROP00000017761 ENSRROP00000017761 ZBTB1 ZBTB1 IFNG IFNG ENSRROP00000017558 ENSRROP00000017558 ENSRROP00000017457 ENSRROP00000017457 CD274 CD274 ZBTB7B ZBTB7B ABL1 ABL1 LOC104676775 LOC104676775 CD276 CD276 AIF1 AIF1 SHH SHH DUSP10 DUSP10 RHOA RHOA AP3D1 AP3D1 PTPN11 PTPN11 PNP PNP CBFB CBFB LILRB4 LILRB4 EFNB1 EFNB1 FLOT2 FLOT2 LCK LCK RASAL3 RASAL3 VAV1 VAV1 EPHB6 EPHB6 CD3E CD3E TYK2 TYK2 SMARCB1 SMARCB1 DOCK8 DOCK8 STAT5B STAT5B CD27 CD27 PTPN22 PTPN22 SMARCD2 SMARCD2 PIK3CA PIK3CA ENSRROP00000011759 ENSRROP00000011759 IL36B IL36B JAK2 JAK2 GPAM GPAM PIK3R6 PIK3R6 ENSRROP00000010437 ENSRROP00000010437 SASH3 SASH3 IGF2 IGF2 CD24 CD24 IL7 IL7 CCL19 CCL19 ENSRROP00000009314 ENSRROP00000009314 IL2 IL2 VCAM1 VCAM1 SMARCE1 SMARCE1 HAVCR2 HAVCR2 LOC104675385 LOC104675385 CD55 CD55 CD86 CD86 TNFSF11 TNFSF11 TFRC TFRC FCHO1 FCHO1 NCK2 NCK2 ZP4 ZP4 RAG1 RAG1 LYN LYN IL12RB1 IL12RB1 ENSRROP00000006428 ENSRROP00000006428 BCL6 BCL6 NCKAP1L NCKAP1L RHOH RHOH SMARCD1 SMARCD1 SMARCA2 SMARCA2 JAK3 JAK3 ENSRROP00000004259 ENSRROP00000004259 TGFBR2 TGFBR2 ENSRROP00000003001 ENSRROP00000003001 SOCS5 SOCS5 RPS3 RPS3 AKT1 AKT1 SOCS1 SOCS1 CD80 CD80 IL4R IL4R IL6 IL6 IL21 IL21 IGFBP2 IGFBP2 HLA-DOA HLA-DOA GLI2 GLI2 NLRP3 NLRP3 RIPK2 RIPK2 SMARCA4 SMARCA4 ABL2 ABL2 PPP3CA PPP3CA CD160 CD160 AP3B1 AP3B1 ENSRROP00000019497 ENSRROP00000019497 HHLA2 HHLA2 NFKBIZ NFKBIZ ITPKB ITPKB SRC SRC SYK SYK BAD BAD VTCN1 VTCN1 CD74 CD74 SIRPB1 SIRPB1 THY1 THY1 CARD11 CARD11 ENSRROP00000021422 ENSRROP00000021422 AMBRA1 AMBRA1 IL15 IL15 HLX HLX PTPRC PTPRC HLA-DRB5 HLA-DRB5 GLI3 GLI3 XBP1 XBP1 HLA-DQA1 HLA-DQA1 GATA3 GATA3 PRKCQ PRKCQ AGER AGER ENSRROP00000023762 ENSRROP00000023762 DNAJA3 DNAJA3 CAV1 CAV1 ENSRROP00000024205 ENSRROP00000024205 SLC7A1 SLC7A1 KITLG KITLG SMARCC2 SMARCC2 ENSRROP00000024470 ENSRROP00000024470 LGALS1 LGALS1 PDCD1LG2 PDCD1LG2 HLA-DPB1 HLA-DPB1 ACTL6B ACTL6B IL27RA IL27RA IGF1 IGF1 ARID1A ARID1A SOX13 SOX13 ICOSLG ICOSLG IL2RG IL2RG FAM49B FAM49B TNFRSF14 TNFRSF14 ZBTB16 ZBTB16 ENSRROP00000026782 ENSRROP00000026782 HLA-DOB HLA-DOB HLA-DPA1 HLA-DPA1 TESPA1 TESPA1 HLA-DMA HLA-DMA MALT1 MALT1 SPTA1 SPTA1 SIRPA SIRPA ICOS ICOS SLAMF1 SLAMF1 ADAM8 ADAM8 LOC104682820 LOC104682820 PTPN6 PTPN6 IL4I1 IL4I1 CD5 CD5 FOXP3 FOXP3 VNN3 VNN3 CCR7 CCR7 IL12RB2 IL12RB2 EGR3 EGR3 SMARCD3 SMARCD3 MYB MYB TNFSF4 TNFSF4 RUNX3 RUNX3 CD1D CD1D SIRPD SIRPD TMIGD2 TMIGD2 LOC104666622 LOC104666622 TNFSF13B TNFSF13B LOC104668444 LOC104668444 ENSRROP00000032658 ENSRROP00000032658 MDK MDK HLA-DRA HLA-DRA PCK1 PCK1 LEF1 LEF1 IL6ST IL6ST DHPS DHPS IL7R IL7R HLA-DQB1 HLA-DQB1 VSIR VSIR CD70 CD70 ARID2 ARID2 LOC104655139 LOC104655139 ENSRROP00000034614 ENSRROP00000034614 IL1B IL1B ZAP70 ZAP70 FADD FADD SHB SHB LOC104655335 LOC104655335 PHF10 PHF10 CD40LG CD40LG ENSRROP00000036200 ENSRROP00000036200 CD209 CD209 TNFSF14 TNFSF14 CORO1A CORO1A TNFRSF13C TNFRSF13C RUNX1 RUNX1 ADA ADA SMARCC1 SMARCC1 CSK CSK ANXA1 ANXA1 IL1RL2 IL1RL2 IL4 IL4 TRAF6 TRAF6 KAT5 KAT5 PRKCZ PRKCZ HLA-E HLA-E VNN1 VNN1 IL12A IL12A PYCARD PYCARD TGFB1 TGFB1 HLA-DRB1-2 HLA-DRB1-2 IHH IHH TNFSF9 TNFSF9 CD81 CD81 CD83 CD83 EFNB2 EFNB2 IL23R IL23R CD28 CD28 ENSRROP00000042123 ENSRROP00000042123 IL18 IL18 BCL10 BCL10 DPP4 DPP4 MAP3K8 MAP3K8 NCK1 NCK1 ENSRROP00000043101 ENSRROP00000043101 PBRM1 PBRM1 SIRPG SIRPG ARID1B ARID1B HLA-DRB1 HLA-DRB1 WNT10B WNT10B CCDC88B CCDC88B CD6 CD6 SART1 SART1 RASGRP1 RASGRP1 LOC104663345 LOC104663345 ENSRROP00000044944 ENSRROP00000044944 EFNB3 EFNB3 NFKBID NFKBID
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL23AInterleukin 23 subunit alpha. (189 aa)
FYNTyrosine-protein kinase. (537 aa)
CLECL1Uncharacterized protein. (162 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1067 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
YES1Tyrosine-protein kinase. (543 aa)
RARARetinoic acid receptor alpha. (478 aa)
ENSRROP00000017761KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (269 aa)
ZBTB1Zinc finger and BTB domain containing 1. (668 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
ENSRROP00000017558Uncharacterized protein. (78 aa)
ENSRROP00000017457HMG box domain-containing protein. (349 aa)
CD274CD274 molecule. (290 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (573 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
LOC104676775Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
CD276CD276 molecule. (496 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
SHHHH_signal domain-containing protein. (141 aa)
DUSP10Dual specificity phosphatase 10. (500 aa)
RHOARas homolog family member A. (193 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1211 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
CBFBCore-binding factor subunit beta. (182 aa)
LILRB4Leukocyte immunoglobulin like receptor B4. (471 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (493 aa)
LCKTyrosine-protein kinase. (561 aa)
RASAL3RAS protein activator like 3. (1011 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
EPHB6EPH receptor B6. (1050 aa)
CD3ECD3e molecule. (198 aa)
TYK2Tyrosine-protein kinase. (1187 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (418 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2078 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
CD27CD27 molecule. (260 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (555 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSRROP00000011759Uncharacterized protein. (274 aa)
IL36BInterleukin 36 beta. (164 aa)
JAK2Tyrosine-protein kinase. (1094 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (464 aa)
ENSRROP00000010437Uncharacterized protein. (235 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
IGF2Insulin like growth factor 2. (236 aa)
CD24Uncharacterized protein. (127 aa)
IL7Interleukin 7. (178 aa)
CCL19C-C motif chemokine. (98 aa)
ENSRROP00000009314Uncharacterized protein. (97 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
SMARCE1HMG box domain-containing protein. (411 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (293 aa)
LOC104675385AIG1-type G domain-containing protein. (323 aa)
CD55CD55 molecule (Cromer blood group). (540 aa)
CD86CD86 molecule. (329 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
TFRCTransferrin receptor. (760 aa)
FCHO1FCH domain only 1. (934 aa)
NCK2Cytoplasmic protein. (382 aa)
ZP4Zona pellucida glycoprotein 4. (539 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
LYNTyrosine-protein kinase. (491 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (661 aa)
ENSRROP00000006428Uncharacterized protein. (70 aa)
BCL6BCL6 transcription repressor. (706 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
RHOHRas homolog family member H. (191 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (482 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1570 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
ENSRROP00000004259TNF receptor-associated factor. (466 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ENSRROP00000003001Uncharacterized protein. (93 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
CD80CD80 molecule. (288 aa)
IL4RInterleukin 4 receptor. (825 aa)
IL6Interleukin 6. (214 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IGFBP2Insulin like growth factor binding protein 2. (325 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
GLI2GLI family zinc finger 2. (1586 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
ABL2Tyrosine-protein kinase. (1164 aa)
PPP3CASerine/threonine-protein phosphatase. (417 aa)
CD160CD160 molecule. (232 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
ENSRROP00000019497Uncharacterized protein. (341 aa)
HHLA2HERV-H LTR-associating 2. (419 aa)
NFKBIZNFKB inhibitor zeta. (723 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (948 aa)
SRCTyrosine-protein kinase. (540 aa)
SYKTyrosine-protein kinase. (635 aa)
BADBCL2 associated agonist of cell death. (167 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
CD74CD74 molecule. (294 aa)
SIRPB1Uncharacterized protein. (397 aa)
THY1Thy-1 cell surface antigen. (161 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
ENSRROP00000021422Uncharacterized protein. (534 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
HLXH2.0 like homeobox. (494 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1311 aa)
HLA-DRB5Ig-like domain-containing protein. (266 aa)
GLI3GLI family zinc finger 3. (1580 aa)
XBP1BZIP domain-containing protein. (380 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (255 aa)
GATA3GATA binding protein 3. (444 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
ENSRROP00000023762Uncharacterized protein. (359 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
ENSRROP00000024205Uncharacterized protein. (176 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1201 aa)
ENSRROP00000024470A_deaminase domain-containing protein. (344 aa)
LGALS1Galectin. (135 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
ACTL6BActin like 6B; Belongs to the actin family. (426 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (208 aa)
ARID1AAT-rich interaction domain 1A. (2289 aa)
SOX13SRY-box transcription factor 13. (621 aa)
ICOSLGUncharacterized protein. (275 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
TNFRSF14TNF receptor superfamily member 14. (283 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
ENSRROP00000026782KH type-2 domain-containing protein. (133 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (273 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (305 aa)
TESPA1Thymocyte expressed, positive selection associated 1. (520 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
MALT1MALT1 paracaspase. (774 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2427 aa)
SIRPAUncharacterized protein. (507 aa)
ICOSInducible T cell costimulator. (199 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (357 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
LOC104682820Uncharacterized protein. (143 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
IL4I1Amine oxidase. (579 aa)
CD5CD5 molecule. (499 aa)
FOXP3Forkhead box P3. (454 aa)
VNN3Vanin 3. (273 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (863 aa)
EGR3Early growth response 3. (387 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (386 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (415 aa)
CD1DCD1d molecule. (337 aa)
SIRPDSignal regulatory protein delta. (197 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (275 aa)
LOC104666622Ig-like domain-containing protein. (276 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
LOC104668444Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (251 aa)
ENSRROP00000032658KH type-2 domain-containing protein. (143 aa)
MDKUncharacterized protein. (143 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
IL6STInterleukin 6 signal transducer. (943 aa)
DHPSUncharacterized protein. (379 aa)
IL7RInterleukin 7 receptor. (459 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (281 aa)
VSIRV-set immunoregulatory receptor. (359 aa)
CD70CD70 molecule; Belongs to the tumor necrosis factor family. (194 aa)
ARID2AT-rich interaction domain 2. (1816 aa)
LOC104655139HMG box domain-containing protein. (406 aa)
ENSRROP00000034614Tyrosine-protein kinase. (465 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
LOC104655335Uncharacterized protein. (511 aa)
PHF10PHD finger protein 10. (497 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
ENSRROP00000036200Uncharacterized protein. (491 aa)
CD209CD209 molecule. (379 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
TNFRSF13CTNF receptor superfamily member 13C. (167 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (482 aa)
ADAA_deaminase domain-containing protein. (443 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa)
CSKTyrosine-protein kinase. (450 aa)
ANXA1Annexin. (346 aa)
IL1RL2Interleukin 1 receptor like 2. (575 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
VNN1Vanin 1. (513 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
HLA-DRB1-2Major histocompatibility complex, class II, DR beta 1. (246 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa)
CD81Tetraspanin. (274 aa)
CD83CD83 molecule. (205 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
IL23RInterleukin 23 receptor. (629 aa)
CD28CD28 molecule. (220 aa)
ENSRROP00000042123Uncharacterized protein. (251 aa)
IL18Interleukin 18. (211 aa)
BCL10BCL10 immune signaling adaptor. (316 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
NCK1Cytoplasmic protein. (377 aa)
ENSRROP00000043101Ig-like domain-containing protein. (244 aa)
PBRM1Polybromo 1. (1725 aa)
SIRPGSignal regulatory protein gamma. (354 aa)
ARID1BAT-rich interaction domain 1B. (1293 aa)
HLA-DRB1Ig-like domain-containing protein. (266 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
CCDC88BCoiled-coil domain containing 88B. (1476 aa)
CD6CD6 molecule. (668 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
RASGRP1RAS guanyl releasing protein 1. (841 aa)
LOC104663345Uncharacterized protein. (518 aa)
ENSRROP00000044944Uncharacterized protein. (64 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
NFKBIDNFKB inhibitor delta. (469 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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