STRINGSTRING
CORO1A CORO1A CX3CL1 CX3CL1 GP1BB GP1BB CYBA CYBA FLNA FLNA FASLG FASLG RYR2 RYR2 ITPR3 ITPR3 JPH4 JPH4 ENSRROP00000034722 ENSRROP00000034722 CHERP CHERP BBC3 BBC3 MCOLN3 MCOLN3 CXCL11 CXCL11 HTT HTT CAPN3 CAPN3 HTR2B HTR2B TRPA1 TRPA1 SRI SRI LETM1 LETM1 RYR3 RYR3 CCR7 CCR7 PTPN6 PTPN6 RYR1 RYR1 CACNA1C CACNA1C ENSRROP00000028974 ENSRROP00000028974 F2 F2 ENSRROP00000028305 ENSRROP00000028305 CEMIP CEMIP CXCR3 CXCR3 LOC104675852 LOC104675852 ENSRROP00000027051 ENSRROP00000027051 ENSRROP00000027041 ENSRROP00000027041 MCOLN2 MCOLN2 DMD DMD DIAPH1 DIAPH1 LHCGR LHCGR PLCG1 PLCG1 F2R F2R ENSRROP00000024190 ENSRROP00000024190 GPER1 GPER1 ITPR2 ITPR2 CXCL9 CXCL9 ITGB3 ITGB3 JPH1 JPH1 PTPRC PTPRC THY1 THY1 NPSR1 NPSR1 NOL3 NOL3 ENSRROP00000019822 ENSRROP00000019822 ENSRROP00000019711 ENSRROP00000019711 JPH3 JPH3 ENSRROP00000019238 ENSRROP00000019238 CALM3 CALM3 CALM2 CALM2 CCL21 CCL21 RASA3 RASA3 TRPM2 TRPM2 JSRP1 JSRP1 ENSRROP00000017624 ENSRROP00000017624 TRPV1 TRPV1 CASQ2 CASQ2 LOC104660236 LOC104660236 ABL1 ABL1 SLC8B1 SLC8B1 GSTO1 GSTO1 GP1BA GP1BA JPH2 JPH2 ANK2 ANK2 LOC104681896 LOC104681896 PRKD1 PRKD1 METTL21C METTL21C LCK LCK PKD2 PKD2 LACRT LACRT FKBP1B FKBP1B NOS1 NOS1 TPCN2 TPCN2 TRDN TRDN NTSR1 NTSR1 ENSRROP00000009633 ENSRROP00000009633 CCL19 CCL19 PRKCE PRKCE LOC104672524 LOC104672524 ANXA6 ANXA6 HTR2A HTR2A ENSRROP00000008584 ENSRROP00000008584 SLC8A1 SLC8A1 F2RL3 F2RL3 LOC104675649 LOC104675649 MTLN MTLN BAX BAX APLNR APLNR LYN LYN PDE4D PDE4D DDIT3 DDIT3 PLN PLN ENSRROP00000004937 ENSRROP00000004937 LIME1 LIME1 CXCL10 CXCL10 PDPK1 PDPK1 SLC25A23 SLC25A23 CHD7 CHD7 P2RX7 P2RX7 GP9 GP9 XCR1 XCR1 HAP1 HAP1 TPCN1 TPCN1 P2RY6 P2RY6 CAMK2D CAMK2D CCR5 CCR5 CD19 CD19 SELENON SELENON PLCG2 PLCG2 ITPR1 ITPR1 CLIC2 CLIC2 AKAP6 AKAP6 ENSRROP00000042119 ENSRROP00000042119 DHRS7C DHRS7C TGFB1 TGFB1 CASQ1 CASQ1 TMEM38B TMEM38B ASPH ASPH PTK2B PTK2B ERO1A ERO1A UBASH3B UBASH3B HRC HRC ATG5 ATG5 CALM1 CALM1 HTR2C HTR2C IBTK IBTK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (208 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
FLNAFilamin A. (2647 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
RYR2Ryanodine receptor 2. (4938 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
ENSRROP00000034722Uncharacterized protein. (107 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (927 aa)
BBC3BCL2 binding component 3. (261 aa)
MCOLN3PKD_channel domain-containing protein. (553 aa)
CXCL11C-X-C motif chemokine. (94 aa)
HTTHuntingtin. (3100 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (826 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1116 aa)
SRISorcin. (198 aa)
LETM1Leucine zipper and EF-hand containing transmembrane protein 1. (739 aa)
RYR3Ryanodine receptor 3. (4851 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
RYR1Ryanodine receptor 1. (4931 aa)
CACNA1CCa_chan_IQ domain-containing protein. (829 aa)
ENSRROP00000028974Uncharacterized protein. (71 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
ENSRROP00000028305Uncharacterized protein; Belongs to the calmodulin family. (167 aa)
CEMIPCell migration inducing hyaluronidase 1. (1361 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
LOC104675852Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
ENSRROP00000027051GST C-terminal domain-containing protein. (218 aa)
ENSRROP00000027041Uncharacterized protein; Belongs to the calmodulin family. (70 aa)
MCOLN2Mucolipin 2. (566 aa)
DMDZZ-type domain-containing protein. (635 aa)
DIAPH1Diaphanous related formin 1. (1238 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
ENSRROP00000024190Protein kinase domain-containing protein. (137 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (341 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CXCL9C-X-C motif chemokine ligand 9. (120 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1311 aa)
THY1Thy-1 cell surface antigen. (161 aa)
NPSR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa)
NOL3Nucleolar protein 3. (260 aa)
ENSRROP00000019822Uncharacterized protein; Belongs to the calmodulin family. (141 aa)
ENSRROP00000019711PDE4_UCR domain-containing protein. (158 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
ENSRROP00000019238Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (785 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (186 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
RASA3RAS p21 protein activator 3. (828 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (333 aa)
ENSRROP00000017624PKD_channel domain-containing protein. (476 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (853 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
LOC104660236Uncharacterized protein. (460 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (584 aa)
GSTO1Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (727 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
ANK2Ankyrin 2. (3938 aa)
LOC104681896Uncharacterized protein. (94 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (895 aa)
METTL21CMethyltransferase like 21C. (264 aa)
LCKTyrosine-protein kinase. (561 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (969 aa)
LACRTLacritin. (137 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1184 aa)
TPCN2Two pore segment channel 2. (752 aa)
TRDNTriadin. (600 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
ENSRROP00000009633G_PROTEIN_RECEP_F1_2 domain-containing protein. (146 aa)
CCL19C-C motif chemokine. (98 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
LOC104672524Uncharacterized protein. (310 aa)
ANXA6Annexin. (673 aa)
HTR2A5-hydroxytryptamine receptor 2A. (472 aa)
ENSRROP00000008584Uncharacterized protein. (263 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
LOC104675649Uncharacterized protein; Belongs to the GST superfamily. (240 aa)
MTLNMitoregulin. (119 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
LYNTyrosine-protein kinase. (491 aa)
PDE4DPhosphodiesterase. (585 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ENSRROP00000004937EF-hand domain-containing protein; Belongs to the calmodulin family. (79 aa)
LIME1Uncharacterized protein. (292 aa)
CXCL10C-X-C motif chemokine. (98 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (356 aa)
SLC25A23Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (529 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
GP9Glycoprotein IX platelet. (177 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
HAP1Huntingtin associated protein 1. (644 aa)
TPCN1Two pore segment channel 1. (879 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
CD19CD19 molecule. (558 aa)
SELENONSelenoprotein N. (553 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
AKAP6A-kinase anchoring protein 6. (2246 aa)
ENSRROP00000042119Uncharacterized protein. (67 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
TMEM38BTransmembrane protein 38B. (276 aa)
ASPHAspartate beta-hydroxylase. (762 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
HRCHistidine rich calcium binding protein. (839 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CALM1Calmodulin 1. (149 aa)
HTR2C5-hydroxytryptamine receptor 2C. (295 aa)
IBTKInhibitor of Bruton tyrosine kinase. (1352 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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