STRINGSTRING
BHLHE23 BHLHE23 HIF1A HIF1A NEUROD4 NEUROD4 ATOH7 ATOH7 IMPDH2 IMPDH2 TGIF2 TGIF2 DCX DCX NEUROD1 NEUROD1 FZD4 FZD4 LOC104660381 LOC104660381 CHD7 CHD7 TOPORS TOPORS HIPK1 HIPK1 ATP2B4 ATP2B4 NR2E3 NR2E3 BBS4 BBS4 ACHE ACHE SERPINF1 SERPINF1 TENT2 TENT2 ATP8A2 ATP8A2 CLIC4 CLIC4 PAX4 PAX4 RS1 RS1 DCLK1 DCLK1 ENSRROP00000005680 ENSRROP00000005680 NRL NRL ZHX2 ZHX2 MEGF11 MEGF11 AHI1 AHI1 ATP2B1 ATP2B1 BAX BAX COL4A1 COL4A1 CYP1B1 CYP1B1 FAT3 FAT3 THRB THRB HIPK2 HIPK2 BMPR2 BMPR2 TULP1 TULP1 GPM6A GPM6A TUB TUB CASP2 CASP2 DLL1 DLL1 CNTF CNTF SDK1 SDK1 TSPAN12 TSPAN12 SKI SKI LAMA1 LAMA1 NECTIN3 NECTIN3 DTNBP1 DTNBP1 LPCAT1 LPCAT1 PROX1 PROX1 FOXN4 FOXN4 BSG BSG SLC1A1 SLC1A1 RHOJ RHOJ ACVRL1 ACVRL1 CDON CDON VSTM4 VSTM4 IMPG2 IMPG2 ROM1 ROM1 LOC104673637 LOC104673637 HPCAL1 HPCAL1 IGSF22 IGSF22 STAT3 STAT3 SLC4A5 SLC4A5 NDP NDP ENSRROP00000018628 ENSRROP00000018628 CLN8 CLN8 ATP2B2 ATP2B2 TFAP2A TFAP2A RHO RHO RP1 RP1 BMPR1B BMPR1B HCN1 HCN1 CLCN2 CLCN2 CALB1 CALB1 DSCAM DSCAM THY1 THY1 SLC17A8 SLC17A8 RP1L1 RP1L1 JMJD6 JMJD6 TCIRG1 TCIRG1 ACTL6A ACTL6A ARHGEF15 ARHGEF15 USP45 USP45 PAX6 PAX6 PAX2 PAX2 LRP5 LRP5 TFAP2B TFAP2B NRP1 NRP1 LAMB2 LAMB2 AGTPBP1 AGTPBP1 SOX9 SOX9 RPE65 RPE65 ACVR2B ACVR2B LHX2 LHX2 VAX2 VAX2 PTPRM PTPRM PDE6C PDE6C RORB RORB TTLL5 TTLL5 MED1 MED1 PTF1A PTF1A SMARCD3 SMARCD3 SOX8 SOX8 HPCA HPCA PDE6A PDE6A TBC1D32 TBC1D32 CABP4 CABP4 NTRK2 NTRK2 LOC104670092 LOC104670092 POU4F2 POU4F2 TGFB2 TGFB2 MAX MAX ZNF513 ZNF513 MFRP MFRP RET RET PROM1 PROM1 ENSRROP00000035356 ENSRROP00000035356 RDH13 RDH13 CRB1 CRB1 GDF11 GDF11 RD3 RD3 GNAT2 GNAT2 NPHP4 NPHP4 ENSRROP00000036406 ENSRROP00000036406 PDGFRB PDGFRB PFDN5 PFDN5 PRPH2 PRPH2 PDE6B PDE6B RPGRIP1L RPGRIP1L SLC17A7 SLC17A7 IHH IHH USH1C USH1C RPGRIP1 RPGRIP1 NOTCH1 NOTCH1 SDK2 SDK2 OBSL1 OBSL1 TTC8 TTC8 CRB2 CRB2 GRM6 GRM6 BARHL2 BARHL2 MAN2A1 MAN2A1 MERTK MERTK NPHP1 NPHP1 NAGLU NAGLU NR2E1 NR2E1 LAMC3 LAMC3 ENSRROP00000043366 ENSRROP00000043366 VSX1 VSX1 NECTIN1 NECTIN1 IGFN1 IGFN1 RPL24 RPL24 SMARCA4 SMARCA4 MFSD2A MFSD2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BHLHE23Basic helix-loop-helix family member e23. (241 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
DCXDoublecortin. (418 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
LOC104660381Uncharacterized protein. (702 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1047 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
NR2E3Nuclear receptor subfamily 2 group E member 3. (410 aa)
BBS4Bardet-Biedl syndrome 4. (347 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (698 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1184 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
PAX4Paired box 4. (351 aa)
RS1Retinoschisin 1. (224 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
ENSRROP00000005680Uncharacterized protein. (141 aa)
NRLNeural retina leucine zipper. (237 aa)
ZHX2Zinc fingers and homeoboxes 2. (837 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
AHI1Abelson helper integration site 1. (1196 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
FAT3Uncharacterized protein. (892 aa)
THRBThyroid hormone receptor beta. (476 aa)
HIPK2Homeodomain interacting protein kinase 2. (1197 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1002 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (542 aa)
GPM6AGlycoprotein M6A. (278 aa)
TUBTubby-like protein; Belongs to the TUB family. (561 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (748 aa)
CNTFCiliary neurotrophic factor. (200 aa)
SDK1Sidekick cell adhesion molecule 1. (1242 aa)
TSPAN12Tetraspanin. (305 aa)
SKISKI proto-oncogene. (770 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
NECTIN3Nectin cell adhesion molecule 3. (538 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (486 aa)
PROX1Prospero homeobox 1. (737 aa)
FOXN4Forkhead box N4. (517 aa)
BSGBasigin (Ok blood group). (362 aa)
SLC1A1Amino acid transporter. (524 aa)
RHOJRas homolog family member J. (214 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
CDONCell adhesion associated, oncogene regulated. (1287 aa)
VSTM4V-set and transmembrane domain containing 4. (310 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1242 aa)
ROM1Retinal outer segment membrane protein 1. (351 aa)
LOC104673637Uncharacterized protein. (113 aa)
HPCAL1Hippocalcin like 1. (193 aa)
IGSF22Immunoglobulin superfamily member 22. (1326 aa)
STAT3Signal transducer and activator of transcription. (802 aa)
SLC4A5Anion exchange protein. (1137 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
ENSRROP00000018628Uncharacterized protein. (88 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (286 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1270 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
RHORhodopsin. (348 aa)
RP1RP1 axonemal microtubule associated. (2152 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (885 aa)
CLCN2Chloride channel protein. (898 aa)
CALB1Calbindin 1. (261 aa)
DSCAMDS cell adhesion molecule. (1894 aa)
THY1Thy-1 cell surface antigen. (161 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
RP1L1RP1 like 1. (2315 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (841 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
PAX6Paired box 6. (458 aa)
PAX2Paired box 2. (417 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
AGTPBP1ATP/GTP binding protein 1. (1272 aa)
SOX9SRY-box transcription factor 9. (509 aa)
RPE65Retinoid isomerohydrolase RPE65. (537 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
LHX2LIM homeobox 2. (406 aa)
VAX2Ventral anterior homeobox 2. (290 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1407 aa)
PDE6CPhosphodiesterase. (501 aa)
RORBRAR related orphan receptor B. (475 aa)
TTLL5Tubulin tyrosine ligase like 5. (1292 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
PTF1APancreas associated transcription factor 1a. (327 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (386 aa)
SOX8SRY-box transcription factor 8. (425 aa)
HPCAHippocalcin. (193 aa)
PDE6APDEase domain-containing protein. (576 aa)
TBC1D32TBC1 domain family member 32. (857 aa)
CABP4Calcium binding protein 4. (275 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
LOC104670092Uncharacterized protein. (69 aa)
POU4F2POU domain protein. (408 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MAXMYC associated factor X. (160 aa)
ZNF513Zinc finger protein 513. (564 aa)
MFRPMembrane frizzled-related protein. (577 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1094 aa)
PROM1Prominin 1. (865 aa)
ENSRROP00000035356PDEase domain-containing protein. (157 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
CRB1Crumbs cell polarity complex component 1. (1233 aa)
GDF11Growth differentiation factor 11. (344 aa)
RD3Retinal degeneration 3, GUCY2D regulator. (195 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
NPHP4Nephrocystin 4. (1333 aa)
ENSRROP00000036406Uncharacterized protein. (99 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
PFDN5Uncharacterized protein. (160 aa)
PRPH2Peripherin 2. (346 aa)
PDE6BPhosphodiesterase. (855 aa)
RPGRIP1LRPGRIP1 like. (1314 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
USH1CUSH1 protein network component harmonin. (899 aa)
RPGRIP1RPGR interacting protein 1. (1282 aa)
NOTCH1Notch receptor 1. (2560 aa)
SDK2Sidekick cell adhesion molecule 2. (2150 aa)
OBSL1Obscurin like 1. (1627 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
GRM6Glutamate metabotropic receptor 6. (877 aa)
BARHL2BarH like homeobox 2. (388 aa)
MAN2A1Alpha-mannosidase. (1144 aa)
MERTKMER proto-oncogene, tyrosine kinase. (997 aa)
NPHP1Nephrocystin 1. (735 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
LAMC3Laminin subunit gamma 3. (1527 aa)
ENSRROP00000043366TRASH domain-containing protein. (158 aa)
VSX1Visual system homeobox 1. (365 aa)
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
IGFN1Immunoglobulin like and fibronectin type III domain containing 1. (3341 aa)
RPL24Ribosomal protein L24. (157 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (530 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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